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Adiff (Adapalene)

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Adiff is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adiff belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Cymbalta, Yasmin, Bystolic, Noroxin, Sumycin, Astelin, Zovirax, Norvasc, Colcrys, Flomax

Also known as: Adapalene


Adapalene is used to treat acne. It works partly by keeping skin pores clear.

Adapalene is available only with your doctor's prescription.


Usual Adult Dose for Acne:

Adiff 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Adiff 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Adiff dosage information


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adiff dosage information

Side effects

The most common side effects associated with Adiff are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Adiff if you are allergic to adapalene.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

It is not known whether Adiff will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Adiff is not approved for use by anyone younger than 12 years old.

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Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model. One of these complications, the separation and migration of the distal tubing to be free intraperitoneally, has been relatively disregarded in the literature both as a phenomenon and as to treatment. De novo and rare inherited copy-number variations in the hemiplegic form of cerebral palsy. Features and complications of nephroptosis causing the loin pain and hematuria syndrome. The surgery of oesophageal webs, peptic strictures and dysrhythmias. To briefly review results of the latest research on approaching antenatal maternal anxiety and stress as distinct constructs within a broad spectrum of maternal antenatal distress and the preventive strategic role of the maternal healthcare practitioner. Complications of percutaneous retrograde arterial catheterization. Automatic map tracer for study of the origin and diffusion of excitation in cardiac structures in vitro. The study included confirmed cases of MID in children less than 15 years of age in Navarra, Spain, between 2008 and 2014.

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(1)H, (13)C and (15)N backbone and side-chain resonance assignment of the LAM-RRM1 N-terminal module of La protein from Dictyostelium discoideum. Maximal extensions of ICA tortuosities perpendicular to the course of the CCA axis are defined as ICA offset. Three dimensions must be considered to analyze the consequences of exposure to ionozing radiation on public health: assessment of exposure, measure of the public health risk, and monitoring the perception of risk by the population. The difference in both the pattern and the magnitude of the effect of cytoskeletal perturbing agent on the viscoelastic properties between HCC cells and hepatocytes may reflect differences in the state of the cytoskeleton structure and function and in the sensitivity to perturbing agent treatment between these two types of cells. L-serine transport in membrane vesicles of Bacillus subtilis energized by NADH or reduced phenazine methosulfate. Using a digital game for training desirable behavior in cognitive-behavioral therapy of burnout syndrome: a controlled study. A controlled trial of a combination of chloroquine with paracetamol in the treatment of acute malaria in a semi-immune population. Importantly, our model predicts that each pair of plasmids will be driven apart in the cell by just a single double helical ParM filament.

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