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Adipine (Nifedipine)

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Adipine is used to treat high blood pressure or angina (chest pain). For high blood pressure: Adipine works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Adipine works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Addos, Calcianta, Calcigard, Casanmil, Cisday, Cordilat, Depin, Duranifin, Fedip, Ficard, Hexadilat, Hypan, Myogard, Nefelid, Nidicard, Nifecard, Nifed, Nifedate, Nifedel, Nifedigel, Nifedipinum, Nifestad, Nifezzard, Nifin, Nilol, Nipidin, Ospocard, Tensomax, Zenusin

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Adalat, Caverta, Flagyl, Benemid, Albenza, Starlix, Sporanox

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adipine OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adipine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adipine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Avian influenza in wild waterfowl and shorebirds in the Donana National Park: Serological survey using the enzyme-linked immunosorbent assay. This article discusses diagnosis, workup, and management of vulvar lichen sclerosus with specific attention on distinguishing it from other dermatologic mimics. Insensible water loss from the Jostra Quadrox D oxygenator: an in vitro study. We signified the risk groups and risk settings of unintentional injuries in Korean daily life. The interplay between Entamoeba and enteropathogenic bacteria modulates epithelial cell damage.

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Conditions determining the excitation threshold of striated muscle fibers. Efficiency of the polymerization system and applying the recommended curing time for light--activated resin-based dental materials are very important to protect the patient from potential hazards of residual monomers. This finding indicates that information provision may prove effective in reducing urgent healthcare use and encourage the design of psycho-educational interventions targeting disease-related cognitions in an attempt to prevent unnecessary healthcare utilization. The parameters investigated to detect HWA disorder were serum ferritin, RBC, Hb, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin. We successfully applied exome sequencing to diagnose the first reported Korean patient with CDG-Ia, which was misdiagnosed as GSD.

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Examination of the skeletal proteome of the brittle star Ophiocoma wendtii reveals overall conservation of proteins but variation in spicule matrix proteins. Transmission electron microscopy was correlated with the autoradiographic results to demonstrate that fibroblasts were dividing on the corneoscleral margin. However, these observations reflect paradoxical features of GCs, since these adrenal stress hormones are heavily involved in both neurodegenerative and neuroprotective processes. Toxin production was greatest when cultures were grown at 30 to 37 degrees C and lowest when cultures were grown at 25 degrees C. As typical of pFL, neoplastic B cells within follicles did not express B-cell leukemia/lymphoma 2 (BCL2). In the Asian literature, minimal changes are considered as one of the endoscopic findings of reflux esophagitis, but the clinical significance is still controversial. In 9 of the 11 patients, elevations in TCC concentrations correlated with disease exacerbations. Are these fewer difficulties and risks in early excision-graft than in the slower methods?. More data and further discussions are needed to decide on the next steps. Gastrointestinal (GI) symptoms in systemic amyloidosis patients are poorly characterized.

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The perioperative morbidity and mortality were comparable to those of an ileal conduit diversion. Dihydroxyacetone and sunless tanning: Knowledge, myths, and current understanding. The purpose of this study was to characterize health status outcomes after transcatheter aortic valve replacement (TAVR) with a self-expanding bioprosthesis among patients at extreme surgical risk and to identify pre-procedural patient characteristics associated with a poor outcome. These data demonstrating autoantibody responses that are limited to particular histone regions support a mechanism by which B cells are selectively activated in murine lupus. Mycosis fungoides successfully treated with cyclophosphamide (Cytoxan). Several studies suggested that statins during hospitalization were associated with better disability outcomes in patients with acute ischemic stroke, but only 1 small randomized trial is available. Multiplex reverse transcriptase-polymerase chain reaction (PCR) was carried out in 16 patients using formalin-fixed, paraffin-embedded tissues and specific primers for COL1A1 and PDGFB. Various quantitative systems have been proposed to examine aphasic oral narratives in English.

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Similar to what was found after gentamicin exposure, cisplatin activates both the c-Jun N-terminal kinase (JNK) and mammalian target of rapamycin (mTOR) pathways. Furthermore, CEMIP silencing sensitized CRC cells to thapsigargin-induced apoptosis. Experimental analysis of sperm competition mechanisms in a wild bird population. The ability of cells and tissues to withstand periods of removal from, or severe changes in, their normal environment is a necessary consequence of many surgical and medical therapies, particularly in the growing area of transplantation. Prevalence, associated factors, mood and cognitive outcomes of traumatic brain injury in later life: the health in men actos medication diabetes study (HIMS). Thus, the surgical care of the lower extremities in spastic cerebral palsy requires that the entire patient be evaluated and all necessary surgical procedures be coordinated. Insights into the equilibrium, kinetic and thermodynamics of nickel removal by environmental friendly Lansium domesticum peel biosorbent. This review will discuss how nanomedicines could help to improve the performance of therapeutics, vaccines and diagnosis of Chagas disease. Here, by profiling an extended region of the 16S rRNA gene in the fecal microbiome, we aimed to elucidate the nature of gut microbiome perturbations during the early phase of infectious diarrhea caused by various etiological agents in Vietnamese children. Mite allergoids coupled to nonoxidized mannan from Saccharomyces cerevisae efficiently target canine dendritic cells for novel allergy immunotherapy in veterinary medicine.

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The concentration of 5-cholestene-3 beta, 7 alpha-diol was very high in the mitochondrial fraction of the CTX-liver. Education of bioterrorism preparedness and response in healthcare-associated colleges--current status and learning objectives development. Since the chromatins are identical in histone variant subtypes, the altered physical properties are not a consequence of changes in histone primary structure during spermiogenesis. Annona muricata leaves extracts prevent DMBA/TPA-induced what allergy medicine is better than zyrtec skin tumorigenesis via modulating antioxidants enzymes system in ICR mice. Measurement of DNA content per cell by flow cytometric analysis revealed two populations of cells in the tumors with ploidies of 2 c and 3.2 c. Dental pulp stem cells (DPSCs) were classified within MSC family, are multipotent, can be isolated from adult teeth, and have been shown to differentiate, under particular conditions, into various cell types including osteoblasts. Since that year, mortality due to rheumatic carditis has rapidly decreased to zero at the hospital we studied (House of the Good Samaritan, Boston), the rate of loss of all murmurs in patients at the study hospital accelerated simultaneously and exceeded 40 percent by 1970, and the rates of decline in national mortality due to rheumatic carditis accelerated fourfold with the advent of antibiotics. Cholesterol biosynthesis and lipid biochemistry in the scolex of Echinococcus granulosus.

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Diagnosis and treatment in threatening cerebrovascular disorders by occlusive processes in the large extracranial vessels. The endothelial nature of both the natural and venous cultures were documented by the presence of characteristic endothelial features, including Weibel-Palade bodies, factor VIII antigen, and morphology. Multivariate analysis of prognostic factors in regional cutaneous metastases of extremity melanoma. Effect of ivacaftor in patients with advanced cystic fibrosis and a G551D-CFTR mutation: Safety and efficacy in an expanded access program in the United States. In this study we provide insights into structural blocks to cross-reactivity and set up guideposts for successful antibody design and re-engineering. Accumulation of unfolded proteins in the ER activates the unfolded protein response (UPR), resulting in transcriptional induction of ER chaperones and ERAD components.

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It is often a challenge to develop selective and robust high performance liquid chromatography (HPLC) methods for the efficient separation of all DRIs. mexicana enzyme crystallized in the T-state, two residues (Lys453 and His480) were proposed to bind the 2-phospho group of the effector. In two cases of post-acute purpura fulminans, two free flaps and three microsurgically dissected flaps were used as primary measures for defect coverage and prograf 30 mg preservation of stump length. In situ twisting for stabilizing and toughening conductive graphene yarns. A large, prospective trial is necessary to determine whether diagnostic testing can be performed in maternal urine or serum rather than amniotic fluid.

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The objectives of this study were to (1) characterize off-label promotion rulings in the UK compared to the whistleblower-initiated cases in the US and (2) shed light on the UK self-regulatory mechanism for detecting, deterring, and sanctioning off-label promotion. Selection of Reference Genes for Real-Time Quantitative PCR in Pinus massoniana Post Nematode Inoculation. Housing is a key determinant of the poor health of Aboriginal Australians. When contextual and content specificity approaches were compared and combined, we observed the strongest predictive validity when the level of specificity is appropriately matched between predictor and criterion. Effect of short imdur 30 mg tablet -chain fatty acids on plasma insulin in ruminant and nonruminant species. Symptom Clusters in Men With Castrate-Resistant Prostate Cancer. Gold nanocage decorated pH-sensitive micelle for highly effective photothermo-chemotherapy and photoacoustic imaging.

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Cryoprotection of red blood cells by 1,3-butanediol and 2,3-butanediol. Circulating cytokine levels are elevated in many neuropathologies and may be a cause of the associated malaise and depression. Primary fluid bolus therapy for infection-associated hypotension in the emergency department. A meta-analysis and review examining a possible role for oxidative stress and singlet oxygen in diverse diseases. It is not uncommon for patients with an advanced disease to express a desire to their physician to hasten their death. Adults referred from the community to hospital eye services for possible glaucoma. Psychological adjustment and behaviours in children of migrant workers in China. PATCHED-1 (PTCH), the receptor for SHH, normally acts to repress SHH signaling.

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Freeze-dried stallion spermatozoa: evaluation of two chelating agents and comparative analysis of three sperm DNA damage assays. In addition, the life prediction of a small punch creep test was carried out and the results of the life prediction predict a reasonable accuracy, which indicates that the small punch creep test is a reliable method for life prediction. The secondary aim was to assess whether the EP group is more likely to have surgical management compared to the PUL ectopic pregnancy group. Major factors encouraging vaccination are proper parental knowledge and the recommendation of the primary physician or cardiologist. The mechanism proposed to explain the origin of the defects was supported by Finite Elements Methods simulations and verified astelin nasal spray generic with in-plant tests. This study improves the understanding of the dynamic link between cigarette smoking and methylation, revealing the continued fluctuation of methylation levels decades after smoking cessation and demonstrating that continuing smoking can have an array of effects. Males can also produce sex pheromones but their study, particularly in butterflies, has received little attention. Data extraction and quality assessment were performed according to the Cochrane review standards. Six healthy pigs underwent laparotomy and were treated with 2 separate ablations (in head and tail of the pancreas).

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