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Agrus (Cetirizine)

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Agrus is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. It is used to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose.

Other names for this medication:
Alcet, Alergid, Alertac, Allerzine, Analar, Anncold, Arizine, Arzyt, Cefid, Ceriz, Cetcold, Cetrad, Cetrine, Cezcold, Citmol, Coldstil, Combit, Elcet, Hycet, Lancizin, Leucold, Metacold, Nacold, Radone, Raincet, Rcold, Rhynal, Satrin, Sinoclear, Sitrizin, Sizon, Smicet, Specet, Tacet, Tercuf, Veecet

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Also known as: Cetirizine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain cough and cold combinations. It may not be specific to Agrus-D. Please read with care.

To help loosen mucus or phlegm in the lungs, drink a glass of water after each dose of this medicine, unless otherwise directed by your doctor.

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

For patients taking the extended-release capsule or tablet form of this medicine:

Swallow the capsule or tablet whole. Do not crush, break, or chew before swallowing. If the capsule is too large to swallow, you may mix the contents of the capsule with applesauce, jelly, honey, or syrup and swallow without chewing.

For patients taking the extended-release oral solution or oral suspension form of this medicine:

Do not dilute with fluids or mix with other drugs.

For patients taking a combination medicine containing an antihistamine and/or aspirin or other salicylate:

Take with food or a glass of water or milk to lessen stomach irritation, if necessary.

If a combination medicine containing aspirin has a strong vinegar-like odor, do not use it. This odor means the medicine is breaking down. If you have any questions about this, check with your pharmacist.


If you overdose Agrus and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Agrus overdosage: extreme sleepiness, confused mental state, weakness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Agrus are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Agrus if you are allergic to cetirizine or levocetirizine.

Ask a doctor or pharmacist if it is safe for you to take cetirizine if you have any medical conditions.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

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To evaluate percutaneous dilatational tracheostomy with and without the use of the bronchoscope and compare the safety and complications of the procedure. This viewpoint could be related to poor motivation and an absence of disease burden due to IFG, such that participants do not feel a need for behavioural change. The pericellular cartilage matrix of chemically fixed specimens often appeared as condensed elements, usually stained with large deposits. However, some indications (particularly aortic interventions) still remain to be determined. Activation of SIK1 by cocaine was further validated by the phosphorylation of TORC1/3, which was followed by the shuttling of TORC proteins from the nucleus to the cytoplasm. Case report on a malignant oncocytoma of the glandula submandibularis in a 56-year old female patient. The purpose of this case report was to present the correction of a horizontally impacted and dilacerated central incisor through 2-stage crown exposure surgery combined with continuous-force orthodontic traction. Analysis of management strategies highlights the centrality of embodied agency in shaping everyday practices and interactions. The establishment of an association of excess adiposity with HL will determine public health preventive measures to fight obesity and eventually novel therapeutic approaches in HL patients. Biomaterials and Fabrication to Optimise Scaffold Properties for Musculoskeletal Tissue Engineering.

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This novel, two-step drug delivery approach can be potentially beneficial for the intracellular delivery of cell impermeable chemotherapeutics. Here, we uncover new cellular factors and mechanisms involved in this process. The authors evaluated patients undergoing immediate breast reconstruction with tissue expanders with varying saline fill volumes to determine patient-, surgery-, and disease-related factors associated with complication risk. These observations suggest that during cellular differentiation the plant Golgi apparatus can be both structurally and functionally reorganized. The interaction of free radicals with antioxidants is a topic of increasing interest in the development of prevention strategies against skin ageing. Suitability of the scaffold for its purpose is determined by factors like size of the pores, its orientation and shape, as well as biocompatibility of the material. Correlation between Tvol and TNM/peritoneal staging derived from histology/surgical findings was evaluated using ROC analysis and compared with CT evaluation of TNM/peritoneal staging. Studies on laticifers have lagged behind in recent years, and data regarding the functional role of laticifers and their fitness benefit still remain elusive.

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