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Alfexo (Fexofenadine)
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Alfexo

Alfexo is an effective medical drug for allergy caused by chemical histamine which is formed in our body naturally and reacts to the external irritants causing the allergic reaction. Alfexo blocks the production and increased activity of histamine receptors as a result of which there is a reduction of the response reaction to the external irritants and the main symptoms of allergy are reduced. This drug helps to reduce cold, lacrimation, sneezing, itching, edema and other allergic symptoms.

Other names for this medication:
Alafex, Allefast, Allermax, Altiva, Arogra, Ergic, Fenadin, Fexamin, Fexidine, Fexofast, Fexofen, Fexofenadine, Fexolast, Fexon, Fexoquin, Fexot, Fexotab, Fexotive, Fexotrol, Fexova, Fexozide, Fextral, Infexo, Intrafen, Madexa, Monten, Novamont, Ofena, Oregra, Rafen, Rhinofex, Ultigra, Zegra, Zllerfax

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Strattera, Calan, Ventolin, Noroxin, Depakote, Avelox, Xalatan

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Also known as: Fexofenadine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Usual Adult Dose for Allergic Rhinitis:

Usual Pediatric Dose for Allergic Rhinitis: 13 years or older: one tablet (180 mg/240 mg) orally once a day.

Detailed Alfexo-D 24 Hour dosage information

Overdose

If you overdose Generic Alfexo and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Fexofenadine/pseudoephedrine dosage information

Side effects

The most common side effects associated with Alfexo are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Ask a doctor or pharmacist if it is safe for you to take Alfexo if you are allergic to any drugs, or if you have kidney disease.

FDA pregnancy category C. It is not known whether Alfexo will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. It is not known whether fexofenadine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Alfexo tablets and capsules may be used to treat seasonal allergy symptoms in children who are at least 6 years old. Alfexo oral suspension (liquid) may be used in children ages 2 through 11. When treating chronic idiopathic urticaria, the liquid may be used in children as young as 2 months old. Do not give this medicine to a child without medical advice.

Alfexo pregnancy and breastfeeding warnings (more detail)

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A randomized controlled trial in the general hospital setting (CC-DIM). Low dose methotrexate therapy is effective in late-onset atopic dermatitis and idiopathic eczema. Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch. In this study, we show that an ybbN-deficient strain displays an increased sensitivity to thermal stress but not to oxidative stress, a normal redox state of its cellular proteins but a decreased expression of several cytoplasmic proteins, including EF-Tu, DnaK, GroEL, trigger factor and several Krebs cycle enzymes, suggesting that the chaperone properties of YbbN are more important in vivo than its redox properties. Here we used ancient DNA preserved in Qinghai Lake sediments to reconstruct the temporal succession of plankton communities in the past 18,500 years.

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Modification of the platelet suspension immunofluorescence test. Non-pseudomonal ecthyma gangrenosum caused by methicillin-resistant Staphylococcus aureus (MRSA) in a chronic alcoholic patient. The study included 61 patients with CHF of ischemic etiology (NYHA II-IV FC) divided between 4 groups. The foreign body had migrated from the left postero-lateral surface of the tongue, anteriorly along the lateral then dorsal surfaces of the tongue, until it self-exfoliated on the right anterior floor of the mouth. Cephalosporin beta-lactamase (cephalosporinase) was purified from a strain of Escherichia coli resistant to beta-lactam antibiotics.

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