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Alpkair (Alprazolam)
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Alpkair

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpkair, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpkair is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Albiz, Alfix, Alpanol, Alprasert, Alprax, Alprazolam, Alsert, Alzopam, Anquil, Anzocalm, Apsolam, Aryalam, Benzolam, Diprex, Elflu, Exiten, Fluzolam, Isorest, Mediprex, Nitril, Prozolam, Rozin, Sowel, Synozolam, Tenrid, Xycalm, Zepro, Zolar, Zolent, Zopral

Similar Products:
Ilosone, Vasotec, Benemid, Claritin, Catapres, Flonase, Cordarone, Pyridium

Also known as: Alprazolam

Description

{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alpkair with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alpkair. Ask your doctor how to avoid withdrawal symptoms when you stop using Alpkair.

Keep track of the amount of medicine used from each new bottle. Alpkair is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Overdose

If you have been prescribed Alpkair for medical reasons, the best way to avoid a Alpkair overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpkair consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpkair are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Alpkair if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alpkair is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alpkair while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alpkair is not approved for use by anyone younger than 18 years old.

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Acute aorto-pulmonary fistula following balloon pulmonary angioplasty after arterial switch operation. Induction of anesthesia for elective surgery at a university hospital. We discuss the ability of the serotonergic system innervating the dorsal cord either to find new targets or to fill vacated sites when one of its putative targets is removed. From May 2008 to July 2012, 160 patients that underwent LC due to acute cholecystitis at Gangnam Severance Hospital, Yonsei University Health System, Seoul, Korea, were enrolled in this study. The weaker interaction of PMNs elastase to TNF is suspected in such neutropenic animals. Cox survival and area under the curve (AUC) (discrimination) analyses of the 2000 to 2002 Medical Expenditures Panel Survey respondent data linked to the National Death Index through 2006, with and without adjustment for sociodemographic characteristics (age, sex, race/ethnicity, education, and income). Does Prostate Size Predict the Development of Incident Lower Urinary Tract Symptoms in Men with Mild to No Current Symptoms?. Pharmacokinetics of Maxing Shigan decoction in normal rats and RSV pneumonia model rats by HPLC-MS/MS.

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There are limited studies about the efficacy of cognitive-behavioural therapy delivered by telephone in reducing parenting stress. Here we combine daily weather records with simulation modelling techniques to explain vector (Aedes aegypti (L.)) persistence within its current and historic ranges in Australia. There is no consensus on which right ventricle (RV) strain parameter should be used in the clinical practice: four chamber RV longitudinal strain (4CH RV-LS) or free wall longitudinal strain (FWLS). Arachidonic acid pathway alterations in cerebrospinal fluid of dogs with naturally occurring spinal cord injury. The proper ratio of FtsZ to FtsA is required for cell division to occur in Escherichia coli. Intercellular adhesion molecule-1 (ICAM-1) expression by lymph node dendritic cells: comparison with epidermal Langerhans cells. Post-LASIK Visual Quality With a Corneoscleral Contact Lens to Treat Irregular Corneas. To study the effects of the combination of adrenaline (epinephrine) and vasopressin compared to adrenaline alone on initial resuscitation success, 24h survival, and neurological outcome in a swine model of asphyxial cardiac arrest (CA).

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These findings indicated that both des-gamma-carboxy prothrombin and alpha-fetoprotein might be useful markers for the prediction of intrahepatic spread of hepatocellular carcinoma. We identified studies relevant to our NMA by performing study searches in databases like Embase, Cochrane, and PubMed, published between August 2010 and June 2014. Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference. Are there any baseline predictors of progesterone elevation (PE) on the day of human chorionic gonadotrophin (hCG) which are not associated with the intensity of ovarian stimulation in women undergoing in vitro fertilization (IVF) using follicle stimulating hormone (FSH) and gonadotrophin-releasing hormone (GnRH) antagonists?. What parameters from 18F-FDG PET/CT are useful in evaluation of adrenal lesions?. CAPS also demonstrates the complementary information value of different patterns for inferring community processes and captures the complexity of community assembly.

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p-Thiophenylalanine-induced DNA cleavage and religation activity of a modified vaccinia topoisomerase IB. Error-related brain activity and error awareness in an error classification paradigm. Drug selection in a regulated society: the Norwegian experience. NBI shows great potential in improving detection rates of OPMD, facilitating better assessment of oral and oropharyngeal SCC, and reducing the risk of recurrence for oral SCC. Mental health legislation recently enacted in various states has improved on older laws by recognizing new procedural rights for patients. The allocation of specialties to hospitals in a Health District. Blood pressure elevation versus abnormal albuminuria in the genesis and prediction of renal disease in diabetes. The decrease of insulin sensitivity with age was higher in female than in male rats. The PD-1 gene was activated in both stimulated 2B4.11 and IL-3-deprived LyD9 cells, but not in other death-induced cell lines that did not show the characteristic features of the classical programmed cell death.

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Early outcomes among those initiating chronic dialysis in the United States. Hypofractionated regimens of whole breast radiation therapy have been variably administered in the adjuvant setting in NSW despite the publication of long-term trial results and consensus guidelines. The Effect of Lifestyle Interventions on Excess Ectopic Fat Deposition Measured by Noninvasive Techniques in Overweight and Obese Adults: A Systematic Review and Meta-Analysis. Blood product transfusion affects respiratory function and is an independent risk factor for respiratory complications after pneumonectomy. Traditionally, reliance has been placed on two-dimensional echocardiographic (2DE) imaging to guide recognition of the specific morphological features. Our results suggest that the introgression in Large White pigs has been strongly determined by the selective pressure acting upon the introgressed AS.

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Potencies on mutagenic and carcinogenic scales were significantly correlated. In the malaria patients an increased level of MBP was maintained during 30 days of treatment with chloroquine. Species with small population in the firings of fast reactions significantly affect both performance and accuracy of this simulation approach. The DNA was ligated to a synthetic, non-phosphorylated adaptor and subsequently amplified in a nested PCR using two oligonucleotides with sequences derived from the adaptor. let-7, miR-26b, miR-145, and miR-183) in cultured human hepatocytes treated with tacrolimus or high glucose, the two independent risk factors of NODALT identified in this cohort. The ductus deferens did not enter the prostate but followed the gubernaculum to the inguinal canal near the stump of the previous operation on the caudal right testis. We recently established organoid models from normal and neoplastic murine and human pancreas tissues.

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Mono-digestion and co-digestion of taro skin, taro flesh, papaya, and sweet potato achieved methane yields from 345 to 411 L kg(-1)VS, indicating the robustness of AD technology. To investigate the clinical value of the ratio of plasma vascular endothelial growth factor level to platelet count (VEGF/PLT) in predicting 28-day prognosis in patients with sepsis. However, almost thirty years after the discovery of the natriuretic peptides the measurement of these peptides, especially the BNP, has not met all the expectations of a simple and useful diagnostic tool in clinical cardiology, possibly due to confounding factors confusing the interpretation of the wall stress effect. The authors describe a Joint Fellowship Curriculum instituted for emergency medicine fellows in diverse fellowships. Systematic study of proteins requires the availability of thousands of proteins in functional format. Finally, morphometric analysis of bezafibrate-induced peroxisome proliferation revealed that the ratio of proliferation obtained by light microscopy in immunostained sections was very close to the results obtained by electron microscopic morphometry. This sets the groundwork for utilizing the natural tropism of CPMV for a therapeutic approach that specifically targets cell types most commonly subverted by chronic viruses. Biosynthesis of xanthan gum by Xanthomonas campestris LRELP-1 using kitchen waste as the sole substrate.

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Since these changes require protein synthesis in the cell body, the needs of the periphery must somehow be communicated to the cell soma. However, antibodies against the alpha chain of VLA-4 were not capable of blocking subsequent migration beneath stromal cells. A 43-case series of consecutive unexplained fetal deaths coming from Northeast Italy, collected in a 5-year period (2011-2015), has been submitted to an in-depth investigation, based on neuropathological and cardiopathological examinations, immunohistochemistry for neuronal nuclear antigen (NeuN), genetic characterization for the serotonin transporter (5-HTT) gene polymorphisms, and toxicological environmental analyses. Pediatric and adult cardiologists, geneticists, genetic counsellors, ethicists, nurses, and qualitative researchers are collaborating to create the Canadian ARVC registry using a web-based clinical database. We proposed a binding model consistent with the available experimental results for the interactions of nC(60) with HSA. We conclude that Strecker stent is useful in the treatment of stenotic hemodialysis arteriovenous fistulas as an adjunct to PTA. We show that reducing NC cohesion by interfering with Cadherin 2 (Cdh2) activity results in FBMNs positioned at the basal side of the neuroepithelium moving apically towards the neural tube midline instead of tangentially towards r6/7. Aging is characterized by common environmental changes, such as hormonal, immunologic, and metabolic disorders. Investigational targeted therapies for the treatment of testicular germ cell tumors.

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We analyzed data on CMH, smoking, and lung function prospectively collected by the Medical Research Council National Survey of Health and Development, a nationally representative British cohort followed since birth in 1946. Pallidal inputs to thalamocortical neurons projecting to the supplementary motor area: an anterograde and retrograde double labeling study in the macaque monkey. Retrospective study of injury rates among children and adults in the Lublin Region of Poland. Health care in cities of the Third World: the situation and some ideas for low cost solutions. The effect of ammonia and pH on brain gamma-glutamyl transpeptidase in young rats. Twenty dental follicles extracted from 12 boys and eight girls between 14 and 18 years of age were examined under phototonic microscopy. Tools to achieve this goal are, for example neuronavigation, functional magnetic resonance imaging (fMRI), tractography, intraoperative cortical stimulation and precise intraoperative definition of tumor margins by virtue of various techniques. CT assessment in patients with LVAD additionally provides valuable information prior to redo sternotomy for pump explantation, revision, or transplantation. The v-erb A protein has sustained two amino acid alterations within its DNA-binding domain relative to that of c-erb A, one of which, at serine 61, is known to be important for v-erb A function in the neoplastic cell. The electrophoretic process, after incubation at low and high ligand concentrations also resulted in separation, for both estrogens, of two binding peaks.

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With the widespread use of early detection tools such as multislice spiral computed tomography (CT), positron emission tomography (PET), and the better survival results after resection of primary lung cancer, more and more MPLC have been detected. Here we characterize diapause responses in the peach fruit moth (PFM) pest, Carposina sasakii Matsumura, which overwinters at the larval stage in soil. At the recent Annual Meeting of the American Headache Society in Washington (DC, USA) the latest scientific advances, as well as their clinical implications, were highlighted. This proposed research aims to use novel nanoparticle sensors and spectroscopic tools constituting surface-enhanced Raman spectroscopy (SERS) and Fluorescence Lifetime imaging (FLIM) to study intracellular chemical activities within single bioremediating microorganism. Around 350 K, breakage of one C-N bond occurs accompanied by further dehydrogenation of the carbon skeleton. Flow over the traveling wavy foil with a built-in rigid flapping plate at its trailing edge has been numerically studied using the multi-relaxation-time lattice Boltzmann method and immersed boundary method. This concurrent chemoradiotherapy protocol showed practical efficacy with high feasibility and acceptable toxicity. The critical role of macrophage migration inhibitory factor in insulin activity. Viewing the Interaction Between Double Strand Deoxyribonucleic Acid and Graphene Oxide via Atomic Force Microscopy.

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Synthesis and substance P antagonist activity of naphthimidazolium derivatives. Inflammation on the cervical Papanicolaou smear: the predictive value for infection in asymptomatic women. Fanconi anemia (FA) is a human rare genetic disorder pepcid 40 mg dosage daily characterized by congenital defects, bone marrow (BM) failure and predisposition to leukemia. Caecal intubation and complication rate of 93 candidates for liver transplantation due to liver cirrhosis were compared with the control rates of our endoscopy unit. Pro: The case for using therapeutic hypothermia after in-hospital cardiac arrest. Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. We have evaluated the effects of four tachykinins on LH release in male rats. In contrast, notifications due to abnormal health survey responses were not associated with increased interventions.

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Three-quarters of patients with stable CAD receive beta-blockers. The overall quality of the studies was very low, and no clear differences were noted between water-based exercise and comparator treatments. Degenerative changes in the material properties of nucleus pulposus and anulus fibrosus promote changes in viscoelastic properties of the whole disc. Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. The long-term gamma-irradiation with low dose rate was shown to cause no effect on the dynamics of animal weight and weight of epididymis changes. At higher doses, L-Leu-OMe, but not its D-stereoisomer, exerted a potent cytotoxic effect alcohol withdrawal ativan dosing on mast cells.

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