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Alpostin (Alprostadil)

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Alpostin injection is used to treat men who have erectile dysfunction (also called sexual impotence). Alpostin is used alone or with medical tests to help diagnose erectile dysfunction that may be caused by nerve or blood vessel problems in the penis.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Alpostin, like its contemporaries Edex, Muse and Caverjet, is an impotence agent and vasodilator known as prostaglandin E1. Alpostin is usually used by men when the blood vessels, nerves and muscles in the penis do not work properly. This unique medication treats every type of erectile dysfunction - vasculogenic, psychogenic, mixed and neurogenic etiology. The prostaglandin E1 relaxes the blood vessels and thins the blood, delivering blood flow to the penile area and causing a hard erection. The main advantage of Alpostin is its quick action, just 5-10 minutes after injection. The effects last for 30-60 minutes but may vary slightly from patient to patient. Alpostin doesn't protect you or your partner from sexually transmitted diseases (including HIV) or from pregnancy.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For the treatment of erectile dysfunction:
    • For injection dosage form:
      • Adults—1.25 to 60 micrograms (mcg) as a single dose once a day. Your exact dose will be determined by your doctor. Inject this medicine very slowly into your penis as shown to you by your doctor 10 to 30 minutes before intercourse. Allow 5 to 10 seconds to completely inject the dose. Do not inject more than one dose within 24 hours. Also, do not use this medicine for more than 2 days in a row or more than 3 times a week.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately. The overdose of the medication may be followed by feeling light-headed, fainting, having a painful or prolonged erection lasting 4 hours or longer.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Alpostin for Injection while in the powder form can be stored at room temperature (between 15 and 25 °C or 59 and 77 °F) for 3 months. After it is mixed, the solution must be used immediately or within 24 hours and not refrigerated or frozen. Suppositories may be stored at room temperature.

Side effects

The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid driving or hazardous activity if you feel light-headed.

Using Alpostin will not protect you from sexually transmitted disease. Ask your doctor how to prevent disease transmission during sex. Sharing drug or medicine needles is never safe.

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