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Anxilam (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Anxilam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Anxilam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpraquil, Alprogard, Alprop, Alprosym, Alproz, Alzolite, Alzom, Anxicalm, Anxit, Axnil, Calmef, Cardilax, Cqlam, Deproz, Dipra, Emcalm, Endolam, Ezoprax, Fledore, Fluxozam, Fultop, Luzarn, Manzolam, Mcalm, Notens, Pecalm, Prazil, Pronil, Pyrex, Resta, Restyl, Rezolam, Sinzolam, Sozox, Tenlax, Texidep, Trapose, Welnorm, Wycalm, Xanti, Zamitol, Zeftra, Zodia

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Cardura, Rogaine, Provera, Ativan, Wellbutrin, Protonix

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Anxilam dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Anxilam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Anxilam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Anxilam if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Anxilam is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Anxilam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Anxilam is not approved for use by anyone younger than 18 years old.

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We investigated whether activated microglia in the thoracic spinal cord contribute to chronic pain in a rat model of CP. In view of the huge diversity of commensals, it is conceivable that they may provide surrogate antigens for activation of autoreactive lymphocytes(s) of other tissue specificities, and might therefore be involved in the etiology of autoimmune diseases more frequently than is currently appreciated. These results provide preliminary support for the notion that discharging appropriate TIA patients, with adequate follow-up, will not adversely affect the recurrence of TIA or stroke within 90 days. Measures included the Yale-Brown Obsessive Compulsive Scale Modified for ORS (ORS-YBOCS), Work and Social Adjustment Scale (WSAS), Depression Anxiety Stress Scales (DASS), and symptom specific questionnaires developed for this study. The aim of this study was to assess long-term pelvic floor symptoms after an obstetric anal sphincter injury (OASI). Hypoadiponectinemia has been linked with disease states, such as obesity, type 2 diabetes, and cardiovascular disease.

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The 2.1, 2.3, and 2.8 ppm resonances were measured at multiple echo times (TEs) by a standard PRESS sequence and by a PRESS sequence consisting of narrow-bandwidth refocusing pulses designed to rewind the J-coupling evolution of the target peak protons in the voxel of interest. Further clinical and in vitro studies are needed to obtain long-term clinical information on zirconia-based restorations. We study, theoretically and experimentally, the dynamical response of macroscopic Turing patterns to a mechanical periodic forcing which implies a sinusoidal modulation of gravity. Although many microorganisms have been used for the bioindustrial generation of valuable metabolites, the productive potential of cyanobacterial species has remained largely unexplored. It was investigated if missingness of the oral health-related items was associated with selected variables of general health. Mild and untypical manifestations may cause diagnostic difficulties. Anti-ageing effects of a new synthetic sphingolipid (K6EAA-L12) on aged murine skin. We analysed the data from 546 socio-economically disadvantaged mother-child pairs to assess the relationship between maternal perceptions of fruit and vegetable affordability and the diets of their children. Post-visit at ophthalmology emergency service: frequency and perception of the doctors on duty and users.

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A case of widespread vertebral metastasis, presenting with myelopathy, from a carotid body tumor is discussed in this paper, along with management strategies. 2011 Humanism in Medicine Essay Contest: third place: The heart in my white coat. Morphometrical and cytomorphological evaluations were performed in 7 cultured lung cancer cell lines and 51 lung adenocarcinoma clinical samples to identify specific cytomorphologic characterization of EGFR-mutated cancer cells compared to the wild type. These findings suggest that TMS acts by adding noise to neuronal processing, at least in an online TMS protocol. It is offered to elderly individuals without known or diagnosed cognitive impairment by volunteers or community practitioners over ten weekly sessions. A method to separate FAME and the linoleic and linolenic acids isomers by GCxGC using an apparatus equipped with a capillary flow technology (CFT) based modulator and a FID detector has been developed.

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A number of pharmacological evidence supports the view that somatostatin (SS) may be importantly involved in the seizure susceptibility both in humans and in laboratory animals. This article presents normative data on the day-to-day operation of partial hospitalization programs affiliated with mental health centers in the State of Indiana. The increased 125I-70 kD binding resulted from increased access of 125I-70 kD to basolateral matrix assembly sites and not from the relocation of binding sites to the apical membrane. Prognosis for patients with glioblastoma (GBM) remains poor, and new treatments are needed. At 11 weeks after resection, animals presented severe renal failure reflected by reduced creatinine clearance, elevated blood urea nitrogen and presence of anemia. Records of 906 patients with tuberculosis, of whom 162 reacted to antituberculous therapy, were analysed. Comparison of outcomes between successful and unsuccessful applicants for VA disability payments. Cardiac atrial natriuretic factor during evolution of congestive heart failure.

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A prospective randomized comparison of left and right radial approach for percutaneous coronary angiography in Asian populations. Photoacoustic imaging aims to visualize light absorption properties of biological tissue by receiving a sound wave that is generated inside the observed object as a result of the photoacoustic effect. In hypertensive subjects, cardiovascular risk reduction is critically related to the decrease of systolic blood pressure (SBP). SFA may regulate ACAT2 expression in human and mouse hepatic cells and in mouse livers. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Individual malaria interventions provide only partial protection in most epidemiological situations. Oculomotor localization relies on a damped representation of saccadic eye displacement in human and nonhuman primates. However, little research has explored how secondary exchange occurs, nor why SSEs do their work. Factors that affect the accuracy of the positron emission tomographic (PET) quantification of cerebral metabolic rates include the spatial resolution of the employed imaging device and the method used for extraction of regional metabolic values from the PET data set.

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An efficient ruthenium(IV) catalyst for the selective hydration of nitriles to amides in water under mild conditions. Neorickettsia (formerly Ehrlichia) risticii is an obligatory intracellular bacterium of digenetic trematodes. Quality of Life With Ivabradine in Patients With Angina Pectoris: The Study Assessing the Morbidity-Mortality Benefits of the If Inhibitor Ivabradine in Patients With Coronary Artery Disease Quality of Life Substudy. Thus, the magnitude of improvement of these aging-related abnormalities differs for ARBs. Fourier transform infrared spectroscopy (FTIR) fingerprints of seed flour and extracts indicated major functional groups such as polysaccharides, lipids, amides, amines and amino acids. Topical corticosteroids seem to be effective in inducing histological remission but may not have similar significant impact in improving clinical symptoms of EoE. Ultrasonography findings of the ONW correlated well with the final diagnosis of papilloedema or pseudopapilloedema, especially when the upper limit of the normal ONW was set at 3.0 mm.

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We studied the effect of short-term (3 h) pancreatic duct obstruction (PDO) on the exocrine pancreas and on the secretion of lysosomal enzymes into the pancreatic juice of rabbits during stimulation by pancreatic secretagogues. In the control LEA rats the enzyme was expressed in most tissues, including the liver. The biotin carboxylase gene encodes a protein of 449 residues that is strikingly similar to amino-terminal segments of two biotin-dependent carboxylase proteins, yeast pyruvate carboxylase and the alpha-subunit of rat what drugs not to take with lipitor propionyl-CoA carboxylase. Construction of a 7-aminocephalosporanic acid (7ACA) biosynthetic operon and direct production of 7ACA in Acremonium chrysogenum. GABAB receptor activation partially inhibits N-methyl-D-aspartate-mediated tyrosine hydroxylase stimulation in rat striatal slices. To determine whether an explained-variance genetic risk score (GRS), with 36 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes (T2D), is also associated with gestational diabetes mellitus (GDM), and with the progression to pre-diabetes and T2D among women with prior GDM. Little is known about the relative contributions of HR and NHEJ to mycobacterial chromosome repair, the factors that dictate pathway choice, or the existence of additional DSB repair pathways. Failure to provide sufficient information to a patient when seeking consent can result in a claim in negligence.

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A human fibrosarcoma cell line, HT-1080, and four new cell lines (HS-16, HS-28, HS-30, and HS-42) were established from untreated patients with mesenchymal chondrosarcoma, peripheral nerve sheath sarcoma, malignant hemangiopericytoma, and mixed mesodermal tumor, respectively, and were used for analysis of mechanisms of intrinsic resistance to methotrexate. Uncoupling proteins (UCPs) belong to a family of mitochondrial carrier proteins that are present in the mitochondrial inner membrane. Although most women received good support from their family members, some were rejected and discriminated against by their family members. The expression of P-gp was evaluated by immunocyto- and histochemical methods, using three different Monoclonal Antibodies C219, JSB-1 and MRK16 directed against separate epitopes of P-gp. Because of the diverse nature of disease manifestations, an HIV Team concept is promoted.

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Detection of neuronal cell death is a standard requirement in cell culture models of neurodegenerative diseases. In cases of doubt, therefore, contrast-enhanced computed tomography of the abdomen is the diagnostic imaging procedure of choice. For comparison, curvature-inducing isotropic inclusions are also simulated. Previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiation. Further, a xenograft tumor model in mice with MCF7 cells demonstrated significantly increased sensitivity towards PARP inhibition under CtIP deficiency. In vivo MR quantification of superparamagnetic iron oxide nanoparticle leakage during low-frequency-ultrasound-induced blood-brain barrier opening in swine. All three patients were male and had an average vasotec 10 mg side effects age of 57 years (range: 32-77 years). The data suggest that increases in beta 2m in measles correlate better with cytokine production than with cell proliferation. In this paper we demonstrate that the purified EGFR can be cosedimented with purified filamentous actin (F-actin) indicating a direct association between EGFR and actin. The aim of this study was to determine the prevalence of renal dysfunction according to the criteria in this proposal.

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Secondly, both mammalian species examined possessed extreme codon bias in genes relating to hair--a tissue unique to mammals. Effects of bariatric surgery on disability pension in Swedish obese subjects. Protein kinases represent one of the largest superfamilies of drugable targets and a major research area for both the pharmaceutical industry and academic groups. Tyrosine hydroxylase (TH) activity, as well as the number of D2-dopaminergic receptors, decreased in the striatum of aged rats, especially in the males in which the decrease in the number of receptors was associated with an increase in their affinity. Transfection of FG cells with a cDNA encoding the integrin beta 3 subunit results in the surface expression of a functional integrin alpha v beta 3 heterodimer providing these cells with novel adhesive and biological properties. The role of calcium antagonists in the treatment of atherosclerosis and hypertension. During the first hour, the JAK-STAT signaling pathway is activated and the expression of 54 genes declines, primarily affecting LE cytoskeletal and chromatin organization as well as a transient reduction in the progesterone, TGFbetaR1, and ACVR1 receptors. Imaging results showed that successful encoding during reappraisal was uniquely associated with greater co-activation of the left inferior frontal gyrus, amygdala, and hippocampus, suggesting a possible role for elaborative encoding of negative memories. Sexually active teenagers are at increased risk of developing cervical abnormalities. The activity of tryptophan and tyrosine hydroxylase were estimated in vivo by measuring the accumulation during 30 min of 5-hydroxytryptophan (5-HTP) and 3,4-dihydroxyphenylalanine (DOPA), respectively, after inhibition of aromatic amino acid decarboxylase by administration of m-hydroxybenzylhydrazine (NSD 1015) (100 mg/kg, i.p.).

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