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Anxilam (Alprazolam)
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Anxilam

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Anxilam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Anxilam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpraquil, Alprogard, Alprop, Alprosym, Alproz, Alzolite, Alzom, Anxicalm, Anxit, Axnil, Calmef, Cardilax, Cqlam, Deproz, Dipra, Emcalm, Endolam, Ezoprax, Fledore, Fluxozam, Fultop, Luzarn, Manzolam, Mcalm, Notens, Pecalm, Prazil, Pronil, Pyrex, Resta, Restyl, Rezolam, Sinzolam, Sozox, Tenlax, Texidep, Trapose, Welnorm, Wycalm, Xanti, Zamitol, Zeftra, Zodia

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Cardura, Rogaine, Provera, Ativan, Wellbutrin, Protonix

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Anxilam dosage information

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Anxilam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Anxilam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Anxilam if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Anxilam is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Anxilam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Anxilam is not approved for use by anyone younger than 18 years old.

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We investigated whether activated microglia in the thoracic spinal cord contribute to chronic pain in a rat model of CP. In view of the huge diversity of commensals, it is conceivable that they may provide surrogate antigens for activation of autoreactive lymphocytes(s) of other tissue specificities, and might therefore be involved in the etiology of autoimmune diseases more frequently than is currently appreciated. These results provide preliminary support for the notion that discharging appropriate TIA patients, with adequate follow-up, will not adversely affect the recurrence of TIA or stroke within 90 days. Measures included the Yale-Brown Obsessive Compulsive Scale Modified for ORS (ORS-YBOCS), Work and Social Adjustment Scale (WSAS), Depression Anxiety Stress Scales (DASS), and symptom specific questionnaires developed for this study. The aim of this study was to assess long-term pelvic floor symptoms after an obstetric anal sphincter injury (OASI). Hypoadiponectinemia has been linked with disease states, such as obesity, type 2 diabetes, and cardiovascular disease.

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The third patient had loss of CM fibers with replacement by connective tissue enough to cause functional disturbances. A meta-analysis of response inhibition and Stroop interference control deficits in adults with traumatic brain injury (TBI). Competition with various saccharides further confirmed that the interaction was via the lectin domain of MBL. Lymph node harvest in colon cancer specimens depends on tumour factors, patients and doctors, but foremost on specimen handling. There is controversy about the variations of antioxidants in skeletal muscle after acute exercise. Immuno-histochemistry showed negative ER, PGR and positive LHR status suggesting the possible angiogenic effect of human chorionic gonadotropin hormone (hCG) in the background.

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A broadband supercontinuum light source with an acousto-optic tunable filter (AOTF) are used to characterize dispersion in two time-domain OCT systems, at 850 and 1300 nm. These studies have extremely important clinical implications since cell sensitivity to injury can seemingly be modified. Three distinct discourse profiles emerged, categorized as follows: confused, impoverished, and inefficient. However, neither purely artificial nor purely biological approaches seem poised to realize the potential of solar-to-chemical synthesis. However, environmental factors have been reported to cause spread of non-adaptive mutations in populations, governed by mechanisms, such as genetic assimilation.

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The glycated form appears to predominate in normal serum, whereas the nonglycated form predominates in the serum of patients with NICTH and renal failure. Here, we show that the hardness of the surficial intertidal sediments varies by a factor of 20-50 due to suction development and suction-induced void state changes in the essentially saturated states of intertidal flats and beaches. The frequency of alpha 2-adrenoceptor restriction fragment length polymorphisms in normotensive and hypertensive humans. As a consequence, a net current could be generated along the lead with only one reservoir, if the lead additionally connects to such a normal-metal loop driven by the time-dependent flux. These dynamic changes in cluster pattern are faithfully simulated by a mathematical model of a Turing field in which an inhibitor of Bmp signaling acts as the Turing activator. Influence of Prior Intense Exercise and Cold Water Immersion in Recovery for Performance and Physiological Response during Subsequent Exercise. Devising syntheses capable of precisely manipulating matter on the nanoscale is central to many areas of research. At the heart of this complex network is the transcription factor trio, Oct4, Sox2 and Nanog, which constitute the ESC transcriptional core. However, the outcomes and sources of revision septoplasty are unclear. Two-dimensional flow-cytometric analysis revealed a fraction of cells distinct from the normal Fucci fluorescence pattern.

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The 2.1, 2.3, and 2.8 ppm resonances were measured at multiple echo times (TEs) by a standard PRESS sequence and by a PRESS sequence consisting of narrow-bandwidth refocusing pulses designed to rewind the J-coupling evolution of the target peak protons in the voxel of interest. Further clinical and in vitro studies are needed to obtain long-term clinical information on zirconia-based restorations. We study, theoretically and experimentally, the dynamical response of macroscopic Turing patterns to a mechanical periodic forcing which implies a sinusoidal modulation of gravity. Although many microorganisms have been used for the bioindustrial generation of valuable metabolites, the productive potential of cyanobacterial species has remained largely unexplored. It was investigated if missingness of the oral health-related items was associated with selected variables of general health. Mild and untypical manifestations may cause diagnostic difficulties. Anti-ageing effects of a new synthetic sphingolipid (K6EAA-L12) on aged murine skin. We analysed the data from 546 socio-economically disadvantaged mother-child pairs to assess the relationship between maternal perceptions of fruit and vegetable affordability and the diets of their children. Post-visit at ophthalmology emergency service: frequency and perception of the doctors on duty and users.

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These data are consistent with previous studies of total sleep deprivation and suggest that dynamic, early adaptive changes or normalization of cerebral metabolism may represent early neurobiological markers of chronic SSRI treatment response in geriatric depression. The ambient temperature and electron-phonon coupling strength influence the amplitude of these oscillations. Perception of own death risk: an assessment of road-traffic mortality risk. Investigations on the assessment of immune responses to live transport stressors using haemograms, clotting times, phenoloxidase activity, phagocytic activity, bacteremia and antibacterial activity and haemolymph protein concentration are described. The goal of our study is to develop a new method to address the cost of MRI by combining innovative acquisition methods and automated post-processing software. In order to better prepare future health care professionals for interprofessional cooperation, interprofessional learning sessions for medical students and physiotherapy apprentices were developed at the University Medical Centre Mannheim, Germany. Reconstruction results using experimental datasets are also provided to validate claims made using these performance metrics. Dyrk1A itself promoted tau E10 inclusion, whereas 9G8 inhibited E10 inclusion, and these actions were variable depending on the cell types.

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The goals of this study were to develop a nude mouse model of FMC tumor growth and metastasis and to measure the expression of genes responsible for lymphangiogenesis, angiogenesis, tumor progression, and lymph node metastasis in FMC tissues and cell lines. A single regular-diameter or even a wide-diameter implant is susceptible to these forces, which may lead to fatigue over the long term. Self-reported use of complementary and alternative medicine (CAM) has been shown to increase following a cancer diagnosis, and breast cancer survivors are the heaviest users among cancer survivors. Our findings suggest that sex reassignment, although alleviating gender dysphoria, may not suffice as treatment for transsexualism, and should inspire improved psychiatric and somatic care after sex reassignment for this patient group. Mediators of physical activity change in a behavioral modification program for type 2 diabetes patients. Eye care practitioners can be confident that modern soft contact lenses do not impair visual performance compared to spectacle lenses for the majority of myopes. The main disease in the differential diagnosis of ALHE is Kimura disease, but the 2 entities have several clinical and histological differences. Sex differences were present in concentrations of red blood cells and CREAT, with higher values in males. Here, we identify restriction-modification (R-M) systems as a barrier to transformation with homeologous DNA and find that R-M systems and several components of the recombination machinery control integration length.

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A prospective randomized comparison of left and right radial approach for percutaneous coronary angiography in Asian populations. Photoacoustic imaging aims to visualize light absorption properties of biological tissue by receiving a sound wave that is generated inside the observed object as a result of the photoacoustic effect. In hypertensive subjects, cardiovascular risk reduction is critically related to the decrease of systolic blood pressure (SBP). SFA may regulate ACAT2 expression in human and mouse hepatic cells and in mouse livers. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Individual malaria interventions provide only partial protection in most epidemiological situations. Oculomotor localization relies on a damped representation of saccadic eye displacement in human and nonhuman primates. However, little research has explored how secondary exchange occurs, nor why SSEs do their work. Factors that affect the accuracy of the positron emission tomographic (PET) quantification of cerebral metabolic rates include the spatial resolution of the employed imaging device and the method used for extraction of regional metabolic values from the PET data set.

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Detection of neuronal cell death is a standard requirement in cell culture models of neurodegenerative diseases. In cases of doubt, therefore, contrast-enhanced computed tomography of the abdomen is the diagnostic imaging procedure of choice. For comparison, curvature-inducing isotropic inclusions are also simulated. Previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiation. Further, a xenograft tumor model in mice with MCF7 cells demonstrated significantly increased sensitivity towards PARP inhibition under CtIP deficiency. In vivo MR quantification of superparamagnetic iron oxide nanoparticle leakage during low-frequency-ultrasound-induced blood-brain barrier opening in swine. All three patients were male and had an average vasotec 10 mg side effects age of 57 years (range: 32-77 years). The data suggest that increases in beta 2m in measles correlate better with cytokine production than with cell proliferation. In this paper we demonstrate that the purified EGFR can be cosedimented with purified filamentous actin (F-actin) indicating a direct association between EGFR and actin. The aim of this study was to determine the prevalence of renal dysfunction according to the criteria in this proposal.

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Secondly, both mammalian species examined possessed extreme codon bias in genes relating to hair--a tissue unique to mammals. Effects of bariatric surgery on disability pension in Swedish obese subjects. Protein kinases represent one of the largest superfamilies of drugable targets and a major research area for both the pharmaceutical industry and academic groups. Tyrosine hydroxylase (TH) activity, as well as the number of D2-dopaminergic receptors, decreased in the striatum of aged rats, especially in the males in which the decrease in the number of receptors was associated with an increase in their affinity. Transfection of FG cells with a cDNA encoding the integrin beta 3 subunit results in the surface expression of a functional integrin alpha v beta 3 heterodimer providing these cells with novel adhesive and biological properties. The role of calcium antagonists in the treatment of atherosclerosis and hypertension. During the first hour, the JAK-STAT signaling pathway is activated and the expression of 54 genes declines, primarily affecting LE cytoskeletal and chromatin organization as well as a transient reduction in the progesterone, TGFbetaR1, and ACVR1 receptors. Imaging results showed that successful encoding during reappraisal was uniquely associated with greater co-activation of the left inferior frontal gyrus, amygdala, and hippocampus, suggesting a possible role for elaborative encoding of negative memories. Sexually active teenagers are at increased risk of developing cervical abnormalities. The activity of tryptophan and tyrosine hydroxylase were estimated in vivo by measuring the accumulation during 30 min of 5-hydroxytryptophan (5-HTP) and 3,4-dihydroxyphenylalanine (DOPA), respectively, after inhibition of aromatic amino acid decarboxylase by administration of m-hydroxybenzylhydrazine (NSD 1015) (100 mg/kg, i.p.).

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