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Apirol (Norfloxacin)
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Apirol

Apirol is a fluoroquinolone antibiotic used to treat bacterial infections of the prostate and urinary tract. Apirol also treats gonorrhea. The dose of Apirol depends on the type of infection being treated.

Other names for this medication:
Alenbit, Apiflox, Apirol, Bactracid, Barazan, Barocul, Baxicin, Constilax, Effectsal, Esclebin, Firin, Flobarl, Flossac, Floxamed, Floxamicin, Floxatrat, Floxinol, Fluseminal, Foxgoria, Niterat, Nofloxan, Nofocin, Noprose, Noracin, Norax, Norcozine, Norflodal, Norflomax, Norfloxacin, Normax, Noroxine, Nufloxib, Oranor, Parcetin, Renor, Rexacin, Sebercim, Shinun, Stbanil, Unasera, Uroseptal, Uroxacin

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Also known as: Norfloxacin

Description

Apirol comes as a tablet to take by mouth. It is usually taken twice a day for 3 to 28 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Apirol. Take Apirol at around the same times every day and try to space your doses 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Apirol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take Apirol at least 1 hour before or 2 hours after meals or after drinking milk or eating dairy products.

Swallow the tablets with a full glass of water.

You should begin to feel better during the first few days of your treatment with Apirol. If your symptoms do not improve or if they get worse, call your doctor.

Take Apirol until you finish the prescription, even if you feel better. Do not stop taking Apirol without talking to your doctor unless you experience certain serious side effects listed in the IMPORTANT WARNING or SIDE EFFECT sections. If you stop taking Apirol too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Apirol is also sometimes used to treat certain infections of the stomach and intestines. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Dosage

You should not use Apirol if you have a history of myasthenia gravis, or if you are allergic to Apirol or similar antibiotics such as ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), and others.

You should not use this medication if you have ever had swelling or tearing of a tendon caused by taking Apirol or similar antibiotics.

Before taking Apirol, tell your doctor if you have a heart rhythm disorder, kidney or liver disease, muscle weakness or trouble breathing, joint problems, a condition called pseudotumor cerebri, a history of seizures, a history of head injury or brain tumor, low levels of potassium in your blood (hypokalemia), a personal or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 2 hours before or after you take Apirol.

Apirol may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking Apirol and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

Overdose

If you overdose Generic Apirol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Apirol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of norfloxacin in the pediatric population. Safety and efficacy have not been established.

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Using the miR-155 can effectively alleviate the lung inflammation in mice with acute lung injury induced by LPS. The coexistent occurrence of a lymphoid neoplasm with adenocarcinoma of the stomach is rare. Two (A and C) belonged to the IA1 gene, two (B and D) were alleles derived from the IA2 gene through transgene amplification, and two (E and F) comprised a third novel locus, IA3 that was excluded from the core region of the golden pheasant MHC-B. Further, we found greater adiposity was related to delayed heart rate recovery following both stress tasks. In the present study, we examined the localization of artificially deposited sub-micron-sized carbon-based particles on the surfaces of needles of Cryptomeria japonica, a typical Japanese coniferous tree species, by field-emission scanning electron microscopy. When applied to couple data, spatial statistics can model within- and between-couple differences with results that are readily accessible for researchers and clinicians. Cationic polysaccharides are attractive candidates for gene delivery. To demonstrate whether the major PB-inducible P-450 subfamily (P-450IIB) could be involved in the metabolic activation of cocaine, rates of cocaine N-demethylation (the first step of cocaine bioactivation) and the rate of irreversible (covalent) binding of tritiated cocaine to hepatic microsomal proteins (a measure for the overall bioactivation) were determined in microsomes from saline or PB-pretreated rats. We found that in the septic control group, mean arterial pressure decreased over the course of the study, and that mitochondrial dysfunction developed in which there was a reduction in maximal respiration.

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For the current analyses we used the same cohort in a new 4-year follow-up study (Visit 2). Prevalence and Predictors of Pre-Diabetes and Diabetes among Adults 18 Years or Older in Florida: A Multinomial Logistic Modeling Approach. The relationship between apathy and endocrine dysfunction, both frequent outcomes of neurological insult, has not yet been investigated in brain tumor survivors. Isolation of Rhizobacteria from Jatropha curcas and characterization of produced ACC deaminase. In both steps, the reactions are clean and the yields of products are high. Quantification of the 5-year incidence of thromboembolic events in U.S. Because the perturbation of zinc homeostasis causes various human diseases, cells need to regulate cellular zinc homeostasis strictly. We conclude that plant density is a modifier of root architecture and that root traits and their utility in breeding for greater productivity have to be understood in the context of high sowing densities. Endometrial adenocarcinoma is a more aggressive disease in black women than it is in whites. In this model, LASV isolated from a lethal human case was highly virulent, while the virus isolated from a nonlethal case elicited mostly mild disease with moderate mortality.

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Behavioral change strategies (eg, goal setting, problem solving, and implementation intentions) were selected (Step 3). To ensure confluency the HAECs were pooled after a brief trypsin/EDTA incubation and seeded onto the ECM of the same HUVECs (6th passage) cell line. The purpose of this study was to assess the added value of H1.5 and PLZF protein expression in the correct delineation of GCTs. Effect of low molecular weight organic acids on the uptake of 226Ra by corn (Zea mays L.) in a region of high natural radioactivity in Ramsar-Iran. Rules for suspecting, diagnosing, and properly managing a pharmacobezoar are highly dependent on the pharmaceutical agent or agents involved. The surface oxidation of sulfide minerals, such as galena (PbS), in aqueous solutions is of critical importance in a number of applications.

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Instead, an increased renal breakdown may have a role in limiting the negative effects of other vasoactive factors on the renal circulation. The extended duration of the oil release from the Deepwater Horizon accident (April 20-July 15, 2010) triggered a need to characterize environmental exposures in four dimensions through sampling and tracking the changes in distributions, concentrations, and compositions of oil and total polycyclic aromatic hydrocarbons (TPAH) in the Gulf of Mexico over time and space. COPD model was established by tobacco inhalation, COPD modeling and NLRP3 knockout mice were treated with similar dose and duration of tobacco inhalation for 12 months, the lung function, lung damage and immune responses were evaluated between control, wild type COPD and NLRP3 knock out C57B1/6 mice. Influence of medium composition on penicillin V production in a stirred tank reactor. This study employs a novel synthesis of tools to help delineate the major genetic changes associated with key adaptive shifts in an extensively recombined bacterial species. The pre-ulcerative phase of carrageenan-induced colonic ulceration in the guinea-pig. Subjects reached out and touched targets and their movements were recorded. Estrogen-dependent activation of neutral cholesterol ester hydrolase underlying gender difference of atherogenesis in apoE-/- mice.

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It was found that the N-terminal acetyl group was indispensable for the reaction with the monoclonal antibody and the N-terminally acetylated pentapeptide, Ac-Met-Asp-Pro-Asn-Cys-OH, was the smallest peptide which exhibited a significant reactivity with the antibody. Polyelectrolyte complex nanoparticles are a promising vehicle for siRNA delivery but suffer from low stability under physiological conditions. A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis. With more cases reported, clinicopathological characteristics and histogenesis are increasingly understood. This case also illustrates the importance of early presentation and emergency intervention in this condition. A better understanding of how interfacial structure affects charge carrier recombination would benefit the development of highly efficient organic photovoltaic (OPV) devices. Theoretically, notochord in the vertebral bodies is not completely degenerative and the remaining tissue persists, producing chordomas. The bleeding point was not determined by CEUS or angiography in one case. Comparative analysis and molecular characterization of a gene BANF1 encoded a DNA-binding protein during mitosis from the Giant Panda and Black Bear. Abstracts to over 4000 papers related to proximal femoral fracture research were screened to identify commonly used scales in the five main categories of general quality of life measures (QoL), Activities of Daily Living scales (ADL), mobility and physical performance scales, disease-specific scales and hip-specific scales.

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Laparoscopic excision of an extra-biliary gallbladder duplication cyst in a 9-month-old infant. Calcium transients evoked by climbing fiber and parallel fiber synaptic inputs in guinea pig cerebellar Purkinje neurons. A birefringent Fourier transform imaging spectrometer with a new lateral shearing interferometer is presented. Fifteen fresh-frozen cadaveric upper extremities were dissected under loupe magnification. Surveillance of congenital anomalies is important to identify potential teratogens. Visual-discrimination deficits after lesions of the centrifugal visual system in pigeons (Columba livia).

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Influence of hip position on the sonographic depth of the sciatic nerve in overweight patients. In order to maintain mosquito control gains, it is critical to develop and evaluate novel bioactive molecules that differ in mode of action from currently used products. The unfortunate but widely held view of epilepsy as being due to occult or evil influences gained adherents even in the medical world during ancient times, and the later acceptance of Christianity allowed theological interpretations of seizures as well. Asymmetric cell division is a universal strategy to generate diverse cell types necessary for patterning and proliferation of all eukaryotes. Mutants defective in DTC1 exhibit phenotypes of an enlarged tapetum and middle layer with delayed degeneration, causing male sterility. Third, in vitro, MARCKS is an F-actin cross-linking protein whose activity is inhibited by PKC-mediated phosphorylation and by binding to calmodulin. Depression is common among persons with diabetes and may have a negative impact on diabetes. Moreover, some perspective utilizations are suggested for future studies.

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