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Askapan (Pantoprazole)

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Askapan is in a class of drugs known as proton pump inhibitors (PPIs). These medications work by blocking cells in your stomach that produce acid. Having less acid in your stomach helps to relieve heartburn.

Other names for this medication:
Acipan, Alpant, Befopan, Dortel, Dycizol, Gredom, Impan, Kurepan, Lupipan, Nupenta, Pacid, Pandot, Panpot, Panray, Pantoat, Pantocar, Pantokan, Pantovar, Panwez, Penkool, Pentona, Pepmark, Peptac, Pintel, Poped, Predom, Prolex, Promtec, Recozol, Sudisol, Sydom, Ulrax, Wetoe, Xepenta

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Also known as: Pantoprazole


Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD) with a history of erosive esophagitis. GERD is a condition in which the acid in the stomach washes back up into the esophagus. This medicine may also be used to treat Zollinger-Ellison syndrome or other conditions (eg, cancer) in which the stomach produces too much acid.

Pantoprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.

This medicine is given only by or under the direct supervision of your doctor.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Use the lowest dose for the shortest amount of time needed to treat your condition.

Pantoprazole is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use pantoprazole injection by yourself.

Pantoprazole tablets are taken by mouth, with or without food. Pantoprazole oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break the tablet. Swallow it whole.

The oral granules should be mixed with applesauce or apple juice and given either by mouth or through a nasogastric (NG) tube.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

Call your doctor if your symptoms do not improve or if they get worse while you are using this medicine.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using pantoprazole.

Pantoprazole may also affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use this medicine.

Store this medicine at room temperature away from moisture, heat, and light.

Detailed Askapan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Askapan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of pantoprazole injection in the pediatric population. Safety and efficacy have not been established.

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Albeit few, pediatric studies involving levosimendan suggest similar pharmacokinetics to adults with heart failure, an efficacy at least equal to that of milrinone, favorable myocardial oxygen effects, and an ability to decrease concomitant catecholamine dosing. Previous studies have reported that the establishment of parasitism is connected to the activation of the phosphatidylinositol-3 kinase (PI3K), which controls important steps in cellular metabolism by regulating the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate. From these results, it is suspected that the astroglial cell lines play an important immunological role in the brain. This is the first-in-human study of a drug-eluting bioresorbable vascular scaffold (BVS) for treatment of peripheral artery disease (PAD) involving the external iliac artery (EIA) and superficial femoral artery (SFA). Blocking ELISA additivity tests were performed to analyse whether MoAbs recognised a common epitope involving a conformation or sequence of the modified peptide (azo-GnRH). There were no important differences affecting the postoperative hospitalization, healing procedure and adhesion of the cuff between women of the three subgroups in both groups. After controlling for donor and recipient characteristics, survival analysis was performed using Cox regression. This study not only reveals the details of conformational coupling in BtuCD-F, it also provides a promising approach to other long-range conformational couplings, e.g., in ABC exporters or other ATP-driven molecular machines. Usefulness of serum S100B as a marker for the acute phase of aquaporin-4 autoimmune syndrome.

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HCV novel therapeutic regimens in Wonderland: A budget impact analysis in the Lombardy Region. Further research on enteric pathogens exposed to this in vivo signal will benefit therapeutic and vaccine development and ultimately enhance our success at combating such elite pathogens. Implementing an exercise-training programme to prevent lower-limb injuries: considerations for the development of a randomised controlled trial intervention delivery plan. Inbreeding effects on reproductive outcome: a study based on a large sample from the endogamous Vadde of Kolleru Lake, Andhra Pradesh, India. Risk factors for suicide among patients with schizophrenia: a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid. Reliability was estimated using internal consistency and validity was assessed using known-groups comparison and convergent validity. Epitopes on S protein, and in particular those contained in its antigenic site. Weight perceptions, disordered eating behaviors, and emotional self-efficacy among high school adolescents. These results confirm those of earlier studies and furthermore suggest that the somata of palisade endings are located close to the extraocular motor nuclei--in this case, probably within the C and S groups around the periphery of the oculomotor nucleus.

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The mechanism of this effect is unknown but it has been evidenced to be dependent on the formation of floating spheroids called embryoid bodies. The lateral upper arm flap (LAF) is used for a pedicled flap with the vascular arcade at the elbow. Our results suggest that excessive daytime sleepiness is related to disease duration, and possibly caused by progressive neurodegeneration. A patient with epidemic nephropathy (NE) and with gastrointestinal symptoms and hemorrhagic gastropathy prompted us to study further 10 consecutive patients with NE. Single-layer anatomical reconstruction of the vesico-urethral anastomosis during robot-assisted laparoscopic prostatectomy (RALP). Recombinant EsCnx and EsCrt (rEsCnx and rEsCrt, respectively) proteins can bind to various Gram-positive and Gram-negative bacteria, as well as to different polysaccharides (LPS and PGN). The focus of the review was on the second-look US characteristics (following BI-RADS criteria) of 26 documented additional malignant lesions of the 76 with successful sonographic correlation from the 123 lesions detected by magnetic resonance imaging (MRI). Amelioration of antigen-induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules. Proponents of CBME have strong reasons to keep developing and supporting this broad movement in medical education. The current study aimed at testing whether compared with other employment groups, fewer leisure activities observed in unemployment may contribute to elevated risk for negative mental health via loss of time structure.

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We tested both black-capped chickadees and humans in a chord discrimination task that replicates and extends prior research with pigeons. The in vivo studies showed that oral lesions from candidal infestation occurred in all mice. The European Working Time Directive has had a well-documented impact on training, and therefore educational opportunities should be maximised. In this study of quality of life outcomes related to different mesh types, the CCS subscales were more sensitive to differences in outcome than the total CCS score for the whole questionnaire. Selected heterozygosity at cis-regulatory sequences increases the expression homogeneity of a cell population in humans. Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging. Purified Px recombined with Ig isolated from pleural fluids from patients with lung adenocarcinoma, but not with Ig from patients with breast carcinoma. To allow comparing new materials the authors have developed an experimental proceeding of which they analyse technical difficulties and limits. Strains representing different chlamydia species were easily distinguishable by this method, as were different serovars of C.

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At the air-water interface, unsaturated wax esters react readily with ozone in ambient air. While the Seebeck coefficient remained constant, a large improvement in the electrical conductivity was observed for thin films processed with high boiling point additives. The agent-based model was parameterized and validated using novel high-content image analysis of mammary acini morphogenesis in vitro with focus on time-dependent cell densities, proliferation and death rates, as well as acini morphologies. demonstrate how distinct blood vessels contribute to HSC maintenance and hematopoiesis in the BM niches. To establish shared and disorder-specific structural, functional, and overlapping multimodal abnormalities in these 2 disorders through a voxel-based meta-analytic comparison of whole-brain gray matter volume (GMV) and functional magnetic resonance imaging (fMRI) studies of inhibition in patients with ADHD and OCD. Patient complained of severe pain and deformity of ankle following injury. Also macrophages showed a highly significant lower expression of VEGFR-1 compared to endothelial cells. From signal transduction of living cells to oxidation and corrosion of metals, mechanical stress intimately couples with chemical reactions, regulating these biological and physiochemical processes.

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Simultaneous quantification of MTC-220 and its metabolites in beagle dog plasma by liquid chromatography-tandem mass spectrometry. The prevalence of anaphylaxis is high in patients who seek medical assistance for drug reactions, but its diagnosis is missed in emergency services, and adrenaline is underused. These noisy models are then used within a probabilistic, or Bayesian framework to provide a coarse 2D dendritic tree segmentation. Vancomycin-associated drug reaction with eosinophilia and systemic symptoms syndrome. Leaf feeding from herbivores reduced both fruit production and seed germination, and leaf herbivory increased with plant patch size. The aim of the present study was to measure stigma among community pharmacists regarding patients with depression, using social distance as a proxy measure.

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Therefore, we prepared a cut-off solution that gives a clear index to distinguish Le(a-b-) sera. The outcome of flow diversion for middle cerebral artery (MCA) aneurysms, one of the most common sites for intracranial aneurysms, has not been defined thoroughly. These data demonstrate that the relatively simple profile of a hormone pulse contains critical temporal information that is transduced into waves of primary response regulatory gene activity. Topically administered leptin was shown to promote wound healing in the oral mucosa by accelerating epithelial cell migration and enhancing angiogenesis around the wounded area. The non-vegetarians were divided into two groups: 31 Catholic nuns and 31 female college students. This study identified several shortcomings in methodology and lack of standardization of current economic evaluations. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. While gift giving exists in the case of middle-size earthquakes, political regimes play a very important part in the overall donation process. Relative to the early expression of the glucagon and insulin genes on embryonic days 10 and 12, respectively, the expression of the somatostatin gene is delayed (day 17).

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Patients who received levetiracetam prophylaxis were matched 1:1 using propensity score matching with those who did not receive the drug. Treatment plans are made for various sites of intracranial lesions with the cones and mMLC. The proliferation of large genomic databases offers the potential to perform increasingly larger-scale genome-wide association studies (GWASs). We report here that in RBL-2H3 cells, p56lyn and pp60c-src are activated after Fc epsilon RI crosslinking, and p56lyn coimmunoprecipitates with Fc epsilon RI. In this paper, we propose a sequential scenario for the conformational transition from the alternative form to the collapsed form, which is partially supported by the mutant W148A simulation. To investigate its clinical course, we reviewed the records of 115 patients with AIDS and central nervous system toxoplasmosis treated at San Francisco General Hospital between 1981 and 1990. And the expressions of neurotropic factors and its corresponding receptors were increased under KXS2012 administration. Unsharpness of generalized measurement and its effects in entropic uncertainty relations. Associations of analytes with markers of obesity and IR including body mass index, waist circumference, homeostasis model assessment (HOMA-IR), and insulin were examined.

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Dobesilate may provide a novel approach to treating drying diseases of the eye. Comparison of Aeromonas salmonicida resistant and susceptible salmon families: a high immune response is beneficial for the survival against Aeromonas salmonicida challenge. This study aimed to determine the impact of information literacy training course on information literacy skills of Isfahan University of Medical Sciences students based on ACRL standard in 2012. Our work underscores the important and complex role of surface glycans regulating cell membrane organization and interaction with downstream partners. A gene ontology analysis showed DNA methylation changes to be selecting genes with different biological processes in exposure status.

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The heart-weight to body-weight ratio, left ventricular dimension, histopathological grades and antimyosin cardiac uptake were significantly lower in the bunazosin group than in the placebo group in protocol-II, but not in protocol-I or protocol-III. Endemic state of goiter and prophylactic iodine in Poland and Europe. Guidelines for treating dissociative identity disorder in adults, third revision: a tour de force for the dissociation field. Furthermore, lysophosphatidic acid (LPA) also significantly recovered the osteogenic differentiation of how to use albendazole oral suspension ip BMSCs in SMG through the F-actin-TAZ pathway. We observed that SI-NET patients expressing Ma2 autoantibody levels below the cutoff had a longer progression and recurrence-free survival compared to those with higher titer. Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration. It is important to study the tissue-specific functions of both proteins, rather than just JNK1, in the onset of toxic liver injury. The present study confirmed the curative effect of GA and MG against iron overload hepatic damage via their potent antioxidant and iron-chelating potential.

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We designed and fabricated a novel terahertz (THz) otoscope to help physicians to diagnose otitis media (OM) with both THz diagnostics and conventional optical diagnostics. The responsibility of hormonal or non-hormonal factors that modulate the metabolism of apolipoprotein C-III is discussed in order to help in the understanding of the physiopathological mechanisms of lipid disorders in these renal diseases. The iterative emergence and infection of transiently resistant subpopulations suggests a new bet-hedging strategy by which viruses could manage to sustain both vertical and horizontal transmission routes throughout an infected population without compromising a stable co-existence with their host. Effect of Long-Term Periodontal Care on Hemoglobin A1c in Type 2 Diabetes. When root-tip cells of Vicia faba were exposed during early and middle interphase to camptothecin (Cpt), the aberrations obtained were exclusively of the chromatid type and tended to be localized in late replicating heterochromatic regions of the chromosomes. The taxonomic challenge posed by cryptic species underlines the importance of using multiple side effects of ambien and alcohol criteria in species delimitation.

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The optimal model was defined as the model with the lowest AICc. Unlike positronemission tomography (PET), SPECT imaging is widely available and can be performed in any department that has access to a rotating gamma camera. The relationships between the initial percentage of labelled cells, cell recovery, non-specific entrapment of unlabelled cells, the purity of the removed fraction, the degree of antigen expression and separation conditions (flow rate and field strength) were determined and used to establish separation conditions that allowed recovery of cells that differ only in the degree of antibody labelling. IL-23 is required for the induction, expansion, maintenance and downstream effector functions of Th17 cells. Effects of Medical Chitosan on Capsular Formation Following Silicone Implant Insertion in a Rabbit Model. Rats and guinea pigs, which have high hepatic gamma-GT activities, excreted large amounts of both Cys-Gly and GS-Cys-Gly. Dynamical transition in proteins and non-Gaussian behavior of low-frequency modes in self-consistent normal mode analysis. The effect of X-irradiation on cell cycle progression and chromatid aberrations in stimulated human lymphocytes using cohort analysis studies. In addition, it is even softer than traditional electrospray ionization. The first patient had a diagnosis of CHARGE syndrome and presented a bilateral persistent petrosquamosal sinus with sigmoid sinus agenesis, which made mastoidectomy for cochlear implantation difficult.

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The reorganization energy due to charge-induced deformations in both nanotubes is found to be in the 30-60 meV range. These results indicate that low concentrations of noradrenaline directly stimulate renin release from JG cells by the activation of beta-adrenoceptors, while high concentrations of noradrenaline inhibit renin release by the activation of alpha 1-adrenoceptors. We retrospectively reviewed the records of all patients undergoing surgical intervention for ovarian tumors at a single institution. We used 2000-2014 BRFSS data to examine the relationship between functional health and frequent mental distress in 51 states. Systemic sclerosis (SSc) caused fibrosis can be fatal and it still lack of effective treatment. Clonal structure of the introduced freshwater snail Potamopyrgus antipodarum (Prosobranchia: Hydrobiidae), as revealed by DNA fingerprinting. 6 of these children had 1 or 2 developmental disabilities, including neurosensory deafness, cerebral palsy, short attention span, perceptual dysfunctions, and learning disability. However, CD25 showed a higher expression of IL-2 on the 4 acquired cases of ocular toxoplasmosis compared to the remainders. Lastly, for most of the measures, those lacking coverage for all 12 months had less access to care compared with either those lacking coverage for 6-11 months, or those lacking coverage for 1-5 months. The quench of fluorescence intensities of the QDs with a 16 nm red shift of the emission maximum and a color change from green to yellow was observed with a slight pH decrease (from 7.0 to 6.8) in the system.

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Cryostat sections showed NOS-positive nerve trunks throughout the circular and longitudinal muscle layers, but a high density of NOS-LI was observed within the submucosal pacemaker region, as predicted from physiological studies. On Lok Senior Health Services--a community care organization for dependent adults. Branching point of the cervical motor branch of the facial nerve. These prodrugs are found to have no gastric ulceration with retained anti-inflammatory activity. For online prediction, the enhanced Recursive Least Square (RLS) filter is applied to estimate sample-by-sample of the EEG signal. Four variables were analysed: place of articulation, total contact, groove width and hold phase duration.

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The Burke-Fahn-Marsden Dystonia Rating scale served as the primary outcome measure. An exercise intensity equivalent to 4 mmol/l of LA was used for the constant workload exercise test. In vitro, the infection of human B-cells with the lymphotropic gammaherpesvirus Epstein-Barr neurontin 600 mg capsule virus (EBV) induces formation of permanently growing lymphoblastoid cell lines (LCL). However, the combination of SCF and TNF-alpha resulted in synergistic growth stimulation in seven of nine different AML specimens investigated. These include chemopreventive activity (reduced number of tumours), as well as enhancement of squamous papilloma progression, which appears to be due to enhanced keratinocyte proliferation and suppression of epidermal maturation.

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Other methods currently used to analyze the gene products of a particular stretch of DNA are the maxicell system ( Chapter 47 ) and the various DNA-dependent in vitro protein synthesis systems ( Chapter 19 ). All consecutive patients managed for cleft lip, alveolus and palate (CLAP) over 7years and 10months were studied. After radiography ruled out acute pathology, an MRI showed increased adipose tissue at the distal aspect of the appendage. In our design and implementation of the Fall TIPS toolkit, we used the Spiral Software Development Life Cycle model. A total of 593 papers were found using the reported searches of which eight represented the best evidence to answer the clinical question. causing ulceroglandular tularaemia, or those with a potential to be used in a bioterrorism event, could rapidly be discriminated from subspecies less virulent for humans. Fabrication and characterization of Pickering emulsions and oil gels stabilized by highly charged zein/chitosan complex particles (ZCCPs). Impacts of epichlorohydrin-dimethylamine on coagulation performance and membrane fouling in coagulation/ultrafiltration viramune drug class combined process with different Al-based coagulants.

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We make this data freely available with a flexible user interface as our microRNA Data Integration Portal--mirDIP ( Furthermore, this strain displayed an altered proteome mainly affecting proteins associated with stress conditions (bfrB, groEL-2, DnaK) that could contribute to the attenuated phenotype observed in mice. A nationwide quality assurance program can describe standards for the practice of pathology and laboratory medicine. We compared the vasodilatation of resistance-type arteries (mesenteric) from angiotensin II-treated PAR2 wild-type mice (WT) induced by PAR2 agonist 2-furoyl-LIGRLO-amide (2fly) to the responses obtained in controls (saline treatment). Single-incision laparoscopic surgery for intra-abdominal metastatic melanoma. gVARVI: A graphical software tool for the acquisition of the heart rate in response to external stimuli.

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The main constraint of classical off-axis reflecting systems is the primary astigmatism that has long been a research topic of interest. The public health investigation was important in establishing that the disease was widespread throughout the community and not as a result to exposure to a single child care setting. These are very convenient for assessing the antiviral activity of compounds. In grafted rats, amphetamine-induced Fos activation was restored to normal or supranormal levels in the anterior and central caudate-putamen (i.e. We used microarray analysis to comprehensively study the miRNA expression profiling of vemurafenib resistant (VemR) A375 melanoma cells in relation to parental A375 melanoma cells. Takotsubo syndrome as a complication of Pickering syndrome, and perhaps hypertensive emergencies. We believe that there is a gap in knowledge and skills in formal research career development programs that will enable physicians, other clinicians, and basic scientists to actively participate in these two translational research strategies. Major ischaemic heart disease events were assessed from hospital notes, death certificates, and electrocardiograms.

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In vitro and in vivo detection of somatostatin receptors in human malignant lymphomas. The T2 resulting from four different data combination techniques was compared with the T2 from CPMG. The zinc finger motif in the noncore region of RAG2 is highly conserved from zebrafish to humans. Heat treatment also increased the fluorescence anisotropy of the nonchannel gramicidin tryptophans. Enantioselectivity of Candida rugosa lipases (Lip1, Lip3, and Lip4) towards 2-bromo phenylacetic acid octyl esters controlled by a single amino acid. Ultrafast multi-slice spatiotemporally encoded MRI with slice-selective dimension segmented. Conflict Resolution in the Clinical Setting: A Story Beyond Bioethics Mediation.

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