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Asuzol (Metronidazole)
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Asuzol

Asuzol eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Amebidal, Amodis, Amrizole, Collazole, Colpofilin, Efloran, Entizol, Flagemed, Flagicure, Ginerella, Gynomix, Gynoplix, Mebadiol, Menilet, Metrogel, Metronex, Metronidazole, Metronide, Metrozole, Nizole, Orogyl, Pharmaflex, Protozol, Rodogyl, Rovamet, Rozex, Rupezol, Torgyl, Trichodazol, Trichostatic, Unigyl, Varizil, Venogyl

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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Asuzol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.

Overdose

Single oral doses of Asuzol, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Asuzol has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Asuzol overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Asuzol dosage information

Side effects

The most common side effects associated with Asuzol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Asuzol if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

you recently drank alcohol; or you took disulfiram (Antabuse) within the past 14 days.

Do not take metronidazole during the first trimester of pregnancy. This medicine can harm an unborn baby. Tell your doctor if you are pregnant.

To make sure Asuzol is safe for you, tell your doctor if you have ever had:

liver disease; kidney disease (or if you are on dialysis); a heart rhythm disorder; Cockayne syndrome (a rare genetic disorder); a stomach or intestinal disease such as Crohn's disease; a blood cell disorder such as anemia (lack of red blood cells) or low white blood cell (WBC) counts; a fungal infection anywhere in your body; or a nerve disorder.

In animal studies, metronidazole caused certain types of tumors, some of which were cancerous. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk.

You should not breastfeed within 24 hours after using Asuzol. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

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Results of a Phase II Study to Evaluate the Efficacy of Docetaxel and Carboplatin in Metastatic Malignant Melanoma Patients Who Failed First-Line Therapy Containing Dacarbazine. We hypothesized that muscle atrophy and fatty infiltration, features of RC muscle degeneration, are predictive of superior humeral head translation and shoulder functional disability. Dok-1 also associated with both the type I and type II activin receptors. The recently developed technology of computerized solid modeling now makes it possible to analyze these parameters in three dimensions. mHealth apps have been lauded as a promising complement to current outpatient treatment and monitoring strategies, but have not yet been widely used to support prostate cancer survivorship needs. In the stationary regime, an exact formula for the mean occupancy of the metastable state is derived, and the phenomenon of enhancement of stability versus temperature is investigated. Histopathological examination revealed a myxoid retroperitoneal liposarcoma. This endogenous NF-kappaB activation stimulates the transcription of pro-inflammatory cytokines thereby commencing an inflammatory cascade within the CF lung. Effect of nonuniform interstitial space properties on impulse propagation: a discrete multidomain model.

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Light-activated bleaching: effects on surface mineral change on enamel. Here we present the Mutual Folding Induced by Binding (MFIB) database, the first systematic collection of complexes formed exclusively by IDPs. All the antibiotics, chloramphenicol, tetracycline, gentamicin, oleandomycin and phosphonomycin induced forward mutation to L-azetidine-2-carboxylic acid resistance in Escherichia coli WP2. Although numerous studies have been published on robotic adrenalectomy (RA) in the literature, none has done a comparison of posterior retroperitoneal (PR) and transabdominal lateral (TL) approaches. Taurolidine susceptibility of methicillin-resistant Staphylococcus pseudintermedius isolates. Letter: Reconsidering Bone Morphogenetic Protein in the Cervical Spine: Selective Use for Managing Type II Odontoid Fractures in the Elderly. Although these bacteria serve rather successfully as an index of fecal pollution of water supplies, their usefulness in measuring fecal pollution in foods is less than satisfactory. IgG antibodies in the six PCD sera bound to discrete cells in the cerebellum of human, rat and mouse (titers 1000-128,000). If further validated, EPs and fluid biomarkers would represent useful outcome measures for clinical trials, being related to specific mechanisms of the ongoing pathologic changes.

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Evaluation of a child safety program based on the WHO safe community model. Each thick filament was surrounded by a number of thin filaments, giving the filament arrangement a rosette appearance in cross-section. Methotrexate as a Corticosteroid-Sparing Agent for Thyroid Eye Disease. Cerebral magnetic resonance (MR) imaging revealed a 2.5 x 2.5 x 3 cm ring-enhanced mass in the subcortical area of the right frontal lobe associated with extensive perifocal brain edema. We report a shivering, jittery newborn who was subjected to a battery of testing, with the only biochemical abnormality being vitamin D deficiency. Paediatric surgical services in remote northern Australia: an integrated model of care. To develop a participatory approach in. These findings may be of value when counseling patients on bladder preservation strategies for muscle-invasive BC.

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The clinical effectiveness of a colored pit and fissure sealant at 36 months. Erythromelanosis follicularis of the face and neck, originally described in Japan by Kitamura et al. The over-all severity of disease was best assessed by using the Karnofsky performance rating. Such dynamics are associated with the loss in forces caused by mechanical instability encountered in muscle diseases and cardiomyopathy and may underlie potential target treatments for such conditions. Genetic factors in arrhythmogenic right ventricular cardiomyopathy: need for a DNA bank!. Left ventricular longitudinal systolic dysfunction is an independent marker of cardiovascular risk in patients with hypertension. This fact is discussed and the parenteral, short-term prophylaxis is recommended. Our knowledge of how acculturative processes affect families remains quite limited. Rather, when Emx2 expression is abolished, the frequency of symmetric divisions that generate two stem cells increases, whereas it decreases when Emx2 expression is enhanced.

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Ultrafiltration (UF) can rapidly and predictably remove extracellular and intravascular fluid volume. Pre-mating and pregnancy stress in rats affects behaviour of grandpups. This entire process was repeated 6 times for each unique combination of pressure, flow rate, and perfusion mode, yielding a total of 144 experiments. Eighty-five patients with rectal adenocarcinoma who underwent total mesorectal excision of the rectum were studied. This study aimed to determine the prevalence of hypovitaminosis D and hyperparathyroidism and their effects on bone turnover and BMD among HIV-infected adolescents in Southeast Asia. Hispanics and non-Hispanic blacks had the greatest prevalence of diabetes, and non-Hispanic whites had the greatest prevalence of cancer and chronic lung disease. Little is known about the frequency and nature of pediatric patient safety events in the out-of-hospital setting.

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The aim of this review is to present an overview of recent findings on the role of PTPN2 in intestinal homeostasis and the impact of dysfunctional PTPN2 on intestinal inflammation. Two labile intermolecular cross-links were isolated in their reduced forms, one of which was identified by high-resolution mass spectrometry as N(in)-(5-amino-5-carboxypentyl)hydroxylysine. Scene transport by HEMS was associated with improved odds of survival compared with GEMS in pediatric trauma patients. The Effects of Red Blood Cell Transfusion on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage. Investigating the Influence of Magnesium Ions on p53-DNA Binding Using Atomic Force Microscopy. To fabricate a nanoemulsion of flunarizine dihydrochloride by using surfactant and co-surfactants. Despite significant advances in combinations of radiotherapy and chemotherapy, altered fractionation schedules and image-guided radiotherapy, many cancer patients fail to benefit from radiation. Quantitative analysis of apoptotic cells revealed an increase in trophoblasts treated with IFNgamma compared to those in normal pregnancy. The effect of repeated administration of insulin on pain threshold and gamma-aminobutyric acid level in mouse brain. A surgical attack on this disorder can be traced to the turn of the century, when experimental work suggested the feasibility of operations of the pancreas.

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Notably, sudden deaths from these diseases are numerically far more common in the much larger population of nonathletes. Bursectomy, a traditional operative procedure to remove the peritoneal lining covering the pancreas and the anterior plane of the transverse mesocolon, has been performed for serosa-positive gastric cancer in Japan and Eastern Asia. Microfiltration: Effect of retentate protein concentration on limiting flux and serum protein removal with 4-mm-channel ceramic microfiltration membranes. Retroperitoneal Gastrointestinal Type Schwannoma Presenting as a Renal Mass. Our results suggest that the observed changes of the polymer matrix within crystalline regions can be attributed to nanoconfinement in the presence of gold nanoparticles. It was reviewed a decade earlier but primarily for the optimization of chemometric models this review presents the reasons it should be used for generalized statistical validation. Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release. In the present research work, succinylated milk proteins were also prepared. Sensitivity and specificity were calculated for various cut-offs of scores and compared to clinical diagnosis.

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The Contribution of Glyphosate to Agriculture and Potential Impact of Restrictions on Use at the Global Level. These functions are served by distinct subtypes of mesodiencephalic dopamine neurons located in the substantia nigra pars compacta and the ventral tegmental area, which form the nigrostriatal, mesolimbic, and mesocortical pathways. Low serum 25(OH)D levels and inadequate sunlight exposure are associated with DES in Korean adults. In developing hygiene strategies, in recent years, the major focus has been on the hands as the key route of infection transmission. While urologists use sonographic examinations commonly, only a small percentage of surgeons are familiar with this method.

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During this period of time, abnormal ocular fluorophotometry, an early change in the eye of diabetic patients, also returned to normal. In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within the body to locally affect the targeted site without damaging intervening tissues. Diet in pregnancy: a randomized controlled trial of nutritional supplements. In conclusion, MIST is gentle, safe, feasible, and effective in preterm infants, and is widely used for surfactant administration with noninvasive respiratory support by neonatologists. Oral bacteria cause infective endocarditis (IE), so severe periodontitis is thought to be high risk for IE. Clinical forms and clinical classification of leptospiral diseases.

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Relation of the Mitral Annular Plane Systolic Excursion to Risk for Intervention in Initially Asymptomatic Patients With Aortic Stenosis and Preserved Systolic Function. Retromer complexes mediate protein trafficking from the endosomes to the trans-Golgi network (TGN) or through direct recycling to the plasma membrane. The techniques employed were injections of modified autologous or incompatible erythrocytes as well as hyperimmunization with material of high antigen activity (e.g. However, subsequent clinical trials failed to show clinical benefits for rhAPC, and an increased incidence of hemorrhage-related adverse events was noted, which prompted the industry to withdraw rhAPC from the market. The ectopic expression of this mutant protein leads to chromosome nondisjunction in male meiosis. Electromagnetic articulograph based on a nonparametric representation of the magnetic field. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses.

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Superacid-promoted reactions of alpha-ketoamides and related systems ultram 25 mg picture . To determine frequency of ADA in relation to B-cell counts, allergic reactions and clinical efficacy in a large cohort of MS-treated patients. Their distribution in bone marrow and secondary lymphoid organs allows an intimate interaction with T- and B-lymphocytes. Furthermore, mice immunized against muIgbeta-hugamma4.Fc displayed a reduced antibody response against an irrelevant antigen. Physicians should take this into account when evaluating polyuria in patients using lithium and when choosing an antidepressant in patients using lithium. While major nursing organizations have expressed a desire to increase the diversity of the nursing workforce, the data show that Latinos lag far behind all other racial and ethnic groups in representation among RNs.

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