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Avomine (Promethazine)

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Avomine is an inexpensive drug used to treat allergic reactions and to treat or prevent nausea and vomiting from illness. It is also used to help treat pain or nausea after surgery.

Other names for this medication:
Abrozin, Avomine, Brumol, Ceedokid, Cofcodyl, Emispan, Enimol, Ethamol, Fevril, Hyperex, Ibuprom, Kelvin, Kidkof, Kosgan, Lagesic, Lincotuss, Paramax, Parapro, Phenomet, Pinex, Primozyn, Promethazine, Promit, Propar, Prophen, Prosed, Prozine, Romet, Synergan, Tussdex, Tymol, Vomica, Zinmol

Similar Products:
Floxin, Abhigra, Lamisil, Nolvadex, Rocaltrol, Remeron, Addyi, Rogaine, Pepcid

Also known as: Promethazine


Promethazine is used to relieve or prevent the symptoms of hay fever, allergic conjunctivitis (inflammation of the eye), and other types of allergy or allergic reactions. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. It can sometimes close up the bronchial tubes (air passages of the lungs) and make breathing difficult .

Promethazine is also used to prevent and control motion sickness, nausea, vomiting, and dizziness. In addition, it may be used to help people go to sleep and control their pain or anxiety before or after surgery or other procedures .

Promethazine may also be used for other conditions as determined by your doctor .

This medicine is only available with your doctor's prescription .


This section provides information on the proper use of a number of products that contain promethazine. It may not be specific to Avomine. Please read with care.

Never take rectal suppositories by mouth.

Wash your hands with soap and water before and after using this medicine.

To insert suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. If the suppository is too soft to insert, chill the suppository in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For allergy symptoms: Adults and teenagers—12.5 milligrams (mg) before meals and at bedtime; or 25 mg at bedtime as needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For prevention of motion sickness: Adults and teenagers—25 mg twice daily; this initial dose should be taken one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. On other days of travel, 25 mg may be taken on arising and again before the evening meal. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For nausea and vomiting: Adults and teenagers—25 mg for the first dose, then 12.5 to 25 mg every four to six hours if needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg every four to six hours as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For sedation: Adults and teenagers—25 to 50 mg. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg. Children younger than 2 years of age—Use and dose must be determined by your doctor . For control of pain or anxiety before or after surgery: Adults and teenagers—50 mg the night before surgery; 25 to 50 mg after surgery. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg the night before surgery or after the surgery. Children younger than 2 years of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Store at room temperature below 30 degrees C away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Avomine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not receive this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine.

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children.

To make sure promethazine is safe for you, tell your doctor if you have:

asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a sulfite allergy; a history of seizures; a weak immune system (bone marrow depression); glaucoma; enlarged prostate or problems with urination; stomach ulcer or obstruction; heart disease or high blood pressure; liver disease; adrenal gland tumor (pheochromocytoma); low levels of calcium in your blood (hypocalcemia); or if you have ever had a serious side effect while using promethazine or any other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether promethazine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

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