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Azihexal (Azithromycin)
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Azihexal

Azihexal is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Other names for this medication:
Amsati, Azidraw, Azifast, Azithrox, Azitromicina, Azomex, Azrolid, Aztrin, Bactexina, Binozyt, Doyle, Ezith, Macrozit, Magnabiotic, Medimacrol, Mezatrin, Momicine, Naxocina, Novozithron, Phagocin, Pretir, Rarpezit, Thiza, Triamid, Tridosil, Ultreon, Unizitro, Zaret, Zedd, Zemycin, Zibramax, Zirocin, Zithrin, Zithromycin, Zitrolid, Zycin

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Also known as: Azithromycin

Description

Azihexal (Azihexal tablets and Azihexal for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azihexal has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azihexal is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azihexal, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azihexal is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azihexal for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. The dose and length of treatment with Azihexal may not be the same for every type of infection. Take each tablet or capsule with a full glass (8 ounces) of water. To use the oral suspension single dose packet: Open the packet and pour the medicine into 2 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away. Azihexal capsules must be taken on an empty stomach. Take the capsule at least 1 hour before or 2 hours after eating a meal Azihexal tablets or powder oral suspension may be taken with or without food. Take the tablet or oral suspension with food if the medicine upsets your stomach. Do not take Azihexal at the same time as taking an antacid that contains aluminum or magnesium. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make Azihexal less effective when taken at the same time. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Azihexal will not treat a viral infection such as the common cold or flu. It is important to take Azihexal regularly to get the most benefit. Store this medication at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.

Overdose

If you take an overdose of Azihexal you should visit your doctor or health care provider immediately. Symptoms of Azihexal overdosage include discomfort in the stomach, diarrhea, retching and nausea.

Storage

Store Azihexal below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Azihexal out of the reach of children and away from pets.

Side effects

The most common side effects associated with Azihexal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of azithromycin injection in the elderly. However, elderly patients are more likely to have age-related heart problems, which may require caution in patients receiving azithromycin injection.

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