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Betacycline (Oxytetracycline)

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Betacycline is a broad-spectrum antibiotic used to treat a wide variety of infections. Betacycline's primary use is for the treatment of acne vulgaris and rosacea. It is also used to treat certain bacterial infections of the lung, skin, genitals and bladder, certain types of infectious diarrhoea and sexually-transmitted diseases (STD).

Other names for this medication:
Betacycline, Cotet, Dynoxytet, Ecomycin, Geomicina, Innolyre, Oxyteracin, Oxytetracycline, Tetracin

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Also known as: Oxytetracycline


Betacycline is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Betacycline is active against a wide range of gram-negative and gram-positive organisms.

The drugs in the Betacycline class have closely similar antimicrobial spectra, and cross resistance among them is common. Microorganisms may be considered susceptible if the M.I.C. (minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M.I.C. is 4.0 to 12.5 mcg/ml.

Susceptibility plate testing: A Betacycline disc may be used to determine microbial susceptibility to drugs in the Betacycline class. If the Kirby-Bauer method of disc susceptibility testing is used, a 30 mcg Betacycline disc should give a zone of at least 19 mm when tested against a Betacycline-susceptible bacterial strain.

Betacyclines are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile, and excreted in the urine and feces at high concentrations and in a biologically active form.


Take Betacycline by mouth with a full glass of water on an empty stomach at least 1 hour before or 2 hours after eating. Do not lie down for 30 minutes after taking Betacycline. Avoid taking milk, dairy products, calcium-enriched juices before and after consuming the drug. It is better to take Betacycline every day at the same time. Betacycline treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions. For children above 8 years of age: the usual daily dose is 25–50 mg per kg of body weight divided into 4 equal doses. For Adults: the usual daily dose is 1–2 g divided in 4 equal doses, depending on the severity of the infection. For treatment of brucellosis, 500 mg oxytetracycline four times daily for 3 weeks should be accompanied by streptomycin, 1 gram intramuscularly twice daily the first week, and once daily the second week. For treatment of uncomplicated gonorrhea, when penicillin is contraindicated, tetracycline may be used for the treatment of both males and females in the following divided dosage schedule: 1.5 grams initially followed by 0.5 gram q.i.d. for a total of 9.0 grams. For treatment of syphilis, a total of 30–40 grams in equally divided doses over a period of 10–15 days should be given. Do not stop taking Betacycline suddenly. Therapy should be continued for at least 24–48 hours after symptoms and fever have subsided.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately. Symptoms of Betacycline overdose: retching, diarrhoea, nausea.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Generic Tetracycline if you are allergic to Generic Tetracycline components.

Do not take Generic Tetracycline while you are pregnant or have nurseling.

Generic Tetracycline only works against bacteria, it does not treat viral infections.

It is forbidden to take Generic Tetracycline by children under 8 years.

Do not use Generic Tetracycline if you are eating or drink dairy products (cheese, yogurt, milk, ice cream).

Try to be careful with Generic Tetracycline usage in case of having kidney or liver disease, allergies, diabetes, asthma.

Try to be careful with Generic Tetracycline usage in case of taking blood thinner such as isotretinoin (such as Accutane); colestipol (such as Colestid) or cholestyramine (such as Questran, Prevalite); blood thinner (such as warfarin (Coumadin)); tretinoin (such as Vesanoid, Renova, Retin-A); minerals (such as iron, zinc, mineral supplements, calcium, over-the-counter vitamin, magnesium); cholesterol-lowering medications such as antacid (such as Milk of Magnesia, Tums, Maalox, Rolaids); products that contain bismuth subsalicylate (such as Pepto-Bismol); penicillin antibiotics (amoxicillin (such as Trimox, Amoxil), dicloxacillin (such as Dynapen), penicillin (such as Pen-Vee K, Veetids, BeePen-VK), oxacillin (such as Bactocill), carbenicillin (such as Geocillin).

Hormonal birth control (eg, birth control pills) may not work as well while you are using Generic Tetracycline. To prevent pregnancy, use an extra form of birth control (eg, condoms).

Try to be careful with sunbeams. Generic Tetracycline makes skin sensitive to sunlight. Protect skin from the sun. Use Generic Tetracycline with great care in case you want to undergo an operation (dental or any other).

Avoid alcohol.

It can be dangerous to stop Generic Tetracycline taking suddenly.

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