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Betrol (Glibenclamide)
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Betrol

Betrol is an inexpensive drug that helps to treat type 2 diabetes. It is slightly less popular than comparable drugs. Betrol is only available as a generic drug; all brands have been discontinued. Betrol is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Afdiex, Aviglen, Benclamet, Betrol, Bionil, Codica, Combidos, Comdiab, Daocon, Diabetnil, Diabetrol, Diolin, Eumet, Glibenclamide, Glibson, Glimsug, Glitrac, Glucomin, Glucosafe, Glucosil, Glucotrac, Glunil, Glutowin, Glybenclamide, Glyboral, Glybovin, Glybovine, Glycurb, Glymep, Iscept, Melitus, Metclam, Metica, Monomet, Sugatrol, Sugnil, Sugronil, Sycored, Triglucored, Triglycomet

Similar Products:
Cardura, Mysoline, Adalat, Dulcolax, Duricef, Zanaflex, Provigil, Ticlid, Flomax, Ovral

Also known as: Glibenclamide

Description

Betrol is used to treat high blood sugar levels caused by a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Betrol belongs to a class of medicines called sulfonylureas. It causes your pancreas to release more insulin into the blood stream. This medicine may be used alone or with another oral medicine such as metformin.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

Dosage

Usual Adult Dose for Diabetes Type 2:

Standard Betrol: -Initial dose: 2.5 mg to 5 mg orally once a day -Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 1.25 to 20 mg orally as a single dose or in divided doses -Maximum dose: 20 mg/day Micronized Betrol: -Initial dose: 1.5 mg to 3 mg orally once a day -Dose titration: Increase in increments of no more than 1.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 0.75 to 12 mg orally as a single dose or in divided doses -Maximum dose: 12 mg/day Comments: -Administer with breakfast or the first main meal of the day -Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs -Once a day therapy is generally satisfactory, however, some patients may have a more satisfactory response with twice-a-day dosing, especially those receiving higher doses. TRANSFER FROM OTHER HYPOGLYCEMIC THERAPY: -Oral Antidiabetic Therapy: No exact dosage relationships exists between standard Betrol, micronized Betrol, or other oral hypoglycemic agents; when transferring patients from other oral hypoglycemic therapy, the maximum starting doses should be observed. -Insulin: --If the insulin dose is less than 20 units per day substitute 2.5 to 5 mg (standard) OR 1.5 to 3 mg (micronized) orally once a day. --If the insulin dose is between 20 and 40 units per day, substitute 5 mg (standard) OR 3 mg (micronized) orally once a day. --If the insulin dose is more than 40 units per day; transition the patient by concomitantly decreasing insulin by 50% and starting Betrol at 5 mg (standard) OR 3 mg (micronized) orally once a day; as insulin is progressively withdrawn, titrate in increments of 1.25 to 2.5 mg (standard) OR 0.75 to 1.5 mg (micronized) orally once a day every 2 to 10 days. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Usual Geriatric Dose for Diabetes Type 2:

Initial dose: 1.25 to 2.5 mg (standard) orally or 0.75 to 1.5 mg (micronized) orally once a day.

Detailed Betrol dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Side effects

The most common side effects associated with Betrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Betrol in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving Betrol.

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The primary analysis comprised 761 patients who completed 5 years follow up, obtained from the prospective South London Stroke Register (1998-2013). Differences in distance and stride profile between both feet were larger at home, than in clinic. To determine the outcome of application of amniotic graft in ocular surface disorders. Serum concentrations of doxycycline were determined before and at various intervals after administration. Quantitative and fingerprinting analysis of Pogostemon cablin based on GC-FID combined with chemometrics. From an analysis perspective, there are several ways to approach RNA-seq data to unravel differential transcript usage, such as annotation-based exon-level counting, differential analysis of the percentage spliced in, or quantitative analysis of assembled transcripts.

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