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Bexomer (Eszopiclone)

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EsBexomer, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia. It is slightly effective for this use. Bexomer is the active dextrorotatory stereoisomer of Bexomer, and belongs to the class of drugs known as cyclopyrrolones. It is also classified as a therapeutic sedative hypnotic and pharmacological cyclopyrrolone.

Other names for this medication:
Bexomer, Eszopiclone, Fulnite, Zolnite, Zopimin, Zopipure

Similar Products:
Viramune, Xalatan, Urispas, Yasmin, Amoxil

Also known as: Eszopiclone


Bexomer is a nonbenzodiazepine hypnotic agent that is a pyrrolopyrazine derivative of the cyclopyrrolone class.

Bexomer is a white to light-yellow crystalline solid. Bexomer is very slightly soluble in water, slightly soluble in ethanol, and soluble in phosphate buffer.

Eszopiclone is formulated as film-coated tablets for oral administration. Bexomer tablets contain 1 mg, 2 mg, or 3 mg eszopiclone and the following inactive ingredients: calcium phosphate, colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide, and triacetin. In addition, both the 1 mg and 3 mg tablets contain FD&C Blue #2.


Read the Medication Guide provided by your pharmacist before you start using Bexomer and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually just before you get into bed. Do not take it with or right after a high-fat or heavy meal since it may not work as well. The dosage is based on your medical condition, age, liver function, other medications you may be taking, and response to treatment. Do not take more of this medication than prescribed because your risk of side effects will increase. The starting dose is 1 milligram at bedtime as directed. That dosage lessens the risk of having trouble safely doing activities requiring alertness the next day (such as driving or operating machinery). Also, you may not be fully alert the next day, yet you think you are fully alert. If you are prescribed the 3 milligram dosage of Bexomer, you should not do activities the next day that require alertness. Ask your doctor or pharmacist for more details.

If you are an older adult or you have liver disease, a low dose will usually be prescribed to lessen the risk of being impaired the next day. Do not stop your medication without talking to your doctor or pharmacist.


According to the U.S. Prescribing Information, overdoses of Bexomer up to 90 times the recommended dose have been reported in which the patient fully recovered. According to the May 2014 edition of the official U.S. Prescribing Information, fatalities have been reported only in cases in which eszopliclone was combined with other drugs or alcohol.

Texas poison control centers reported that during 2005–2006 there were 525 total Bexomer overdoses recorded in the state of Texas, the majority of which were intentional suicide attempts.

If consumed within the last hour, Bexomer overdose can be treated with the administration of activated charcoal or via gastric lavage.


Store at 25 degrees C (77 degrees F); excursions permitted to 15 to 30 degrees C (59 to 86 degrees F).

Side effects

The most common side effects associated with Bexomer are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Bexomer can cause side effects that may impair your thinking or reactions. You may still feel sleepy the morning after taking the medication. Until you know how this medication will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

Do not drink alcohol while you are taking Bexomer. It can increase some of the side effects of Bexomer, including drowsiness.

Do not take other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxants, and medicine for depression or anxiety).

Avoid taking Bexomer during travel, such as to sleep on an airplane. You may be awakened before the effects of the medication have worn off. Amnesia (forgetfulness) is more common if you do not get at least 8 hours of sleep after taking Bexomer.

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