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Biclar (Clarithromycin)
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Biclar

Biclar is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections,lyme disease,strep throat,skin infections, H. pyloriinfection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma,chlamydiaand mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Other names for this medication:
Ciclinil, Clabact, Clarimed, Claripen, Claritrox, Claritt, Claromycin, Claryl, Clarytas, Clasine, Clathrocyn, Clonocid, Clormicin, Eliben, Emimycin, Ezumycin, Fromilid, Gervaken, Glartin, Hecobac, Helozym, Italclar, Kailasa, Kalecin, Karid, Klabion, Klariger, Klarit, Klarithrin, Klaritpharma, Klazidem, Kleromicin, Larizin, Laromin, Macladin, Maclar, Macrol, Macromicina, Preclar, Rolacin, Veclam, Vikrol, Zeclar

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Also known as: Clarithromycin

Description

Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection.

Clarithromycin belongs to the class of medicines, known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain clarithromycin. It may not be specific to Biclar. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You may take this medicine with meals or milk or on an empty stomach. However, clarithromycin extended release tablets should be taken with food.

If you are using the extended-release tablets:

Swallow the tablet whole. Do not break, crush, or chew it. While taking the extended-release form of this medicine, a part of the tablet may pass into your stools. This is normal and is nothing to worry about.

Measure the oral liquid with a marked measuring spoon, syringe, or cup. The average household teaspoon may not hold the right amount of liquid. Shake the bottle well before each use.

If you are taking clarithromycin and zidovudine, these medicines should be taken at least 2 hours apart.

Keep using this medicine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release tablets): For bacterial infections: Adults—1000 milligrams (mg) once a day for 7 to 14 days. Children—Use and dose must be determined by your doctor. For community-acquired pneumonia: Adults—1000 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension and tablets): For bacterial infections: Adults—250 to 500 milligrams (mg) every 12 hours for 7 to 14 days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 12 hours for 10 days. Infants younger than 6 months of age—Use and dose must be determined by your doctor. For community-acquired pneumonia: Adults—250 milligrams (mg) every 12 hours for 7 to 14 days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. Infants younger than 6 months of age—Use and dose must be determined by your doctor. For prevention or treatment of Mycobacterium avium complex (MAC) infection: Adults—500 milligrams (mg) 2 times a day. Children 20 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight, up to 500 mg, 2 times a day. Children younger than 20 months of age—Use and dose must be determined by your doctor. For treatment of ulcers associated with H. pylori: Adults—500 milligrams (mg) every 8 hours for 14 days in combination with omeprazole, 500 mg every 12 hours in combination with amoxicillin and lansoprazole for 10 or 14 days, or 500 mg every 12 hours in combination with amoxicillin and omeprazole for 10 days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Biclar and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Biclar overdosage: nausea, vomiting, diarrhea, abdominal discomfort.

Storage

Store Biclar at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Biclar out of the reach of children and away from pets.

Side effects

The most common side effects associated with Biclar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of clarithromycin to treat bacterial infections in children younger than 6 months of age, and to prevent and treat Mycobacterium avium complex in children younger than 20 months of age. Safety and efficacy have not been established in these age groups.

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A three-dimensional structure of histo-aspartic protease (HAP), a pepsin-like enzyme from the causative agent of malaria Plasmodium falciparum, is suggested on the basis of homologous modeling followed by equilibration by the method of molecular dynamics. Samples were analyzed in parallel on CyFlow miniPOC, FACSCount CD4 and FACSCalibur to assess CyFlow miniPOC precision and accuracy. Our 1st experience with cobalt 60 irradiator in the therapy of retinoblastomas. Upon charge injection, cell volume expansion is observed, due to charge accumulation along an axis orthogonal to the layer planes. Knowledge, attitude and practice of exercise for plasma blood glucose control among patients with type-2 diabetes. Here we demonstrate that cisplatin (CDDP) and etoposide (VP-16) induce nuclear translocation of NF-kappaB in prostate cancer cell lines, followed by secretion of IL-6. Clinical outcomes and mortality before and after implementation of a pediatric sepsis protocol in a limited resource setting: A retrospective cohort study in Bangladesh. Further reduction of Notch2 gene dosage in Notch2 conditional/mutant (N2(F/LacZ)AlbCre) animals further enhanced IHBD abnormalities and concomitant liver pathology.

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