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Biger (Atorvastatin)
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Biger

Biger is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.

Other names for this medication:
Atocor, Atorsan, Atorvox, Atroact, Aztor, Cardyl, Cardyn, Delipost, Lipinor, Lipivastin, Lipizem, Lipobi, Lipodial, Locol, Lorvaten, Lowlipen, Prevencor, Sortis, Stacor, Stator, Tarimyl, Tiginor, Torvacard, Trova, Zarator

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Also known as: Atorvastatin

Description

Generic Biger is made by highly educated specialists to combat high cholesterol diseases (heart attack, stroke). Target of Generic Biger is to control and decrease level of cholesterol. Generic Biger acts as an anti-high cholesterol remedy. Generic Biger operates by reducing decrease level of cholesterol. Biger is also known as Atorvastatin, Atorbest, Agitor, Attor, Atorlip, Lipvas, Sortis, Torvast, Torvacard, Totalip, Tulip. Generic Biger is HMG-CoA reductase inhibitor (statin). Generic name of Generic Biger is Atorvastatin. Brand name of Generic Biger is Biger.

Dosage

Take Biger exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Biger is usually taken once a day, with or without food. Take the medicine at the same time each day.

Do not break an Biger tablet before taking it, unless your doctor has told you to.

You may need to stop using this medicine for a short time if you have:

uncontrolled seizures; an electrolyte imbalance (such as high or low potassium levels in your blood); severely low blood pressure; a severe infection or illness; or surgery or a medical emergency.

It may take up to 2 weeks before your cholesterol levels improve, and you may need frequent blood test. Even if you have no symptoms, tests can help your doctor determine if Biger is effective.

Biger is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Biger dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Biger are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Biger if you are allergic to atorvastatin, or if you have:

liver disease; or if you are pregnant or breastfeeding.

Atorvastatin can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Biger and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Atorvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking Biger.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

liver problems; muscle pain or weakness; kidney disease; diabetes; a thyroid disorder; or if you drink more than 2 alcoholic beverages daily.

Biger can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Atorvastatin is not approved for use by anyone younger than 10 years old.

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The staminodes of the fourth androecial whorl are comparable to the staminodes in Potameia, but the staminodes of the third androecial whorl of Syndiclis are relatively larger than the staminodes in Potameia. Symptoms of attention-deficit/hyperactivity disorder (ADHD) were first described more than 100 years ago. Employing home blood glucose monitoring and either frequent insulin injections or a portable insulin infusion pump, painful peripheral neuropathy and autonomic gastrointestinal neuropathy improved after five and 12 months of therapy, respectively. Comparing the Effect of Auriculotherapy and Vitamin B6 on the Symptoms of Premenstrual Syndrome among the Students who Lived in the Dorm of Isfahan University of Medical Sciences. Beta-blocking agents in congestive heart failure: for each heart failure patient?. However, since ICT protocols in different studies varies a lot, a comparative and consistent statement of benefits is difficult. The mechanisms of acquired fluconazole resistance of Candida glabrata in non-biofilms have been elucidated, but the relevance of them relative to C.

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Mini-trabeculectomy as initial surgery for medically uncontrolled glaucoma. Further fine specificity delineation was accomplished by examination of cross-reactivity patterns to several mammalian albumins. Survival of patients starting RRT has improved substantially in last decade, overall, by age and for diabetic patients. Cervical cancer is a preventable disease with a regular screening program. The combination of cefepime and vancomycin is commonly used as an empiric antimicrobial regimen. Reversal of Low Donor Chimerism after Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion: A Prospective Phase II Multicenter Trial.

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High profile cases have highlighted failure to provide dignified care for older people in hospitals. We studied the effect of graded aortic blood pressure reduction on left ventricular (LV) blood flow in anesthetized, autonomically blocked, open-chest dogs at constant heart rate and mean left atrial pressure. School-Based Health Centers and Adolescent Substance Use: Moderating Effects of Race/Ethnicity and Socioeconomic Status. Effect on opinion change of similarity between the communicator and the audience he addressed. Histamine-insulin antagonism in relation to rat liver and muscle glycogen turnover. Pre-clinical evidence demonstrates that expression of miRNAs is differentially altered during stress. Subthalamic-pallidal interactions are critical in determining normal and abnormal functioning of the basal ganglia. Adverse viral and medication effects on adipose tissue contribute to the development of metabolic disease in HIV-infected persons, but T cells also have a central role modulating local inflammation and adipocyte function. Intestine of the rat was simple, but cecum had a shape as a stomach.

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Long-range surface plasmon polariton waveguides embedded in fluorinated polymer. Polyadenylated RNA from PRL-stimulated pigeon (Columba livia) crop was used as template to produce a cloned cDNA library in plasmids. A standardized treatment regimen has yet to be established, and therapy plans require a multidisciplinary approach, involving gynecology, cardiothoracic surgery, and pulmonology. Muscle with all these properties may be assumed to be irreversibly damaged. Prescription Opioids and Treatment in Rural Australia: A Failure of Policy for Indigenous Australians.

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CGS 9896 retarded the onset of convulsive fits caused by isoniazid without preventing the decrease in GABA levels produced by that drug. To assess the availability of key resources for the management of maternal sepsis and evaluate the feasibility of implementing the Surviving Sepsis Campaign (SSC) recommendations in Malawi and other low-resource settings. Though these infants are now apparently fit, renal damage has occurred and this may eventually give rise to features indistinguishable from chronic pyelonephritis. An X-ray of the knee was arranged but showed no abnormality to explain the pain. Frailty is an independent predictor of mortality, but is significantly less likely in patients receiving high-volume care. Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells. We found no difference in primary graft patency when aspirin or aspirin with dipyridamole was compared to a vitamin K antagonist or when clopidogrel with aspirin was compared to aspirin alone. Recent observations on Cestodes tetrarhynques of the collection of Oceanographic Museum of Monaco.

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Consecutive patients treated with rivaroxaban for deep vein thrombosis or pulmonary embolism, enrolled into Mayo Thrombophilia Clinic Direct Oral Anticoagulants Registry between March 1, 2013, and April 30, 2015, were followed prospectively to evaluate the efficacy and safety of this therapy. Yet, evidence to define optimal cut-offs for mild cognitive impairment (MCI) after stroke is limited. The new dipole-beamforming algorithm is developed by modifying the basic source definition used for beamforming. Reconciling existing psychiatric medical records with the new American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. HCQ significantly reduced soluble TF levels in patients with aPL.

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Distinct roles of multiple isoforms of CaMKII in signaling to the nucleus. For this sake, a development of a method for fast separation, preventing denaturation and preserving their biological activity was necessary. When compared to control group (untreated), the protein contents, the volume of myocytes, the numbers of fibrocasts in Ang II group increased. We observed significant dose-dependent protection of CGNs with PB2 for all of the above insults, with the greatest neuroprotective effect being observed under conditions of nitrosative stress. The clinical outcomes were analyzed and compared between the two groups. Paediatric early warning score (PEWS) assessment tools can assist healthcare providers in the timely detection and recognition of subtle patient condition changes signalling clinical deterioration. A combination of extensive soft tissue damage caused by penetrating injuries, blast injury to the lungs and tympanic membranes, and burns are common among survivors. Anti-vascular endothelial growth factor treatment induces blood flow recovery through vascular remodeling in high-fat diet induced diabetic mice. As a result, differences in DNA looping structure are associated with variation in gene expression and cell state.

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Its continued usefulness derives from the fact that it is based on a numerical solver for complex coupled biological equilibria rather than on closed-form analytical equations for the binding isotherms. Chondrosarcoma of the jaws arises from vestigial rests and is considered a rare entity, although it is more common than its benign counterpart. The nonlinearity of these processes and the absence of suitable instrumentation require an enhanced modelling effort and modern kinetic parameter estimation strategies. Colonic mast cell numbers (toluidine blue) and collagen (type I mRNA expression) were evaluated. The placenta and decidual weight increased before day 18 and 14 of pregnancy, and then decreased with gestational day. Physical exercise can be part of treatment in patients with chronic fatigue syndrome (CFS), where the aim would be to improve strength and endurance through increasing physical exercise (intensity and time) without aggravating symptomatology. Autoimmune diseases refer to a spectrum of diseases characterized by an active immune response against the host, which frequently involves increased autoantibody production. Migration of cultured fetal spinal cord astrocytes into adult host cervical cord and medulla following transplantation into thoracic spinal cord.

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Amyloid beta-protein precursor (APP), a type I membrane protein, is cleaved by primary alpha-or beta-secretase and secondary gamma-secretase. This study evaluated the effects of PGA1 on B-16 melanoma-bearing mice. Anatomic limitations dictated the need for a left renal snorkel in order to augment the proximal seal zone. Our experience supports the use of anterior segment surgery to clear the nidus of disease combined with intravitreal voriconazole to prevent recurrence of the infection. Changes in the structure of serum albumin upon interaction with metabolites. The age ranged from 33 to 77 years (mean: 50.4 years), with a clinical course from 1 month to 8 years. Differences in genotype frequencies of ADIPOQ c.276 and RETN c.-180 suggest a need for studies on a larger cohort of patients with AN. The data provided by the biochemical and genetic analysis have indicated that pts44 mutation occupies the region between purC and ptsI loci on the chromosome of Sh. Conformation of protein-polysaccharide complex from bovine nasal septum.

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Regularly arrayed Si cylinders with hexagonal lattice fabricated on polyethylene terephthalate (PET) flexible substrate are exploited to detect applied strain and surface dielectric environment by measuring transmission spectra. In each patient the teeth on one side were acid-etched and the contralateral teeth were microetched prior to acid-etching. Lateral cephalograms of 128 patients (66 males, 62 females) with cleft lip and palate, and 125 (60 males, 65 females) non syndromic patients without cleft lip and palate were selected at random from archive. These TUNEL-positive cells showed neither cytochrome c mitochondrial translocation usually found in typical apoptotic cells nor DNA laddering indicative of oligonucleosomal DNA fragmentation. Arrhythmogenic right ventricular dysplasia and sudden cardiac death in endurance athletes. The clinical syndrome caused by paratyphoid fever overlaps with other febrile illnesses and cannot be distinguished from typhoid fever. However, the epidemiologic data on this cause and effect relation are inconsistent. No significant association was found between modeled RF-EMF exposure and the investigated outcomes. S seems present as sulfate (probably as sulfated sugars), sulfonate, sulfite, and sulfoxide groups and, in a lesser extent, as sulfur-containing amino acids.

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LVH and CAC independently predict CV events in asymptomatic hypertensive patients. Secondary failure is frequently caused by antibodies against immune-biologicals, known as anti-drug antibodies (ADA). Tritium enrichment by gas-solid chromatography: technic for low-level analysis. The optimal CE values can then be determined by comparing the extracted ion chromatograms for the ion pairs of interest among serial scans. The authors expect this review to be a useful overview of the current state of the art of nanomedicine research and industrial production, and the future opportunities of personalized medicine in the upcoming years. Here we show in vitro angiogenesis following the distribution of the MN conjugated with growth factors. Engineering intranasal mRNA vaccines to enhance lymph node trafficking and immune responses. Collaborative care using videoconferencing to facilitate mental health specialty consults has demonstrated effectiveness in the treatment of depression, PTSD, and also ADHD in pediatric populations. In response to skeletal muscle injury, loss of MKP-5 decreased activation of the mitochondrial apoptotic pathway involving the signal transducer and activator of transcription 3 (STAT3) and increased expression of the anti-apoptotic transcription factor Bcl-2. As hepatic progenitor cells have bipotency and high proliferation ability, they could present a potential source for generating transplantable cells or as a liver study model.

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Because these manifestations have been associated to the spectrum of IgG4-related disease (IgG4-RD), we hypothesized that both diseases could overlap. Multiple aspects of these regulatory processes contribute to physiological and pathophysiological regulation of the pulmonary circulation, and create potentially novel therapeutic targets for the treatment of pulmonary vascular disease. The panel reviewed the effectiveness of primary and specialist care settings in the UK and USA and identified the principal clinical needs of patients with recurrent genital herpes. Relation between liquid-holding recovery, DNA repair, and mitotic recombination in the rad3 mutant of Saccharomyces cerevisiae after treatment with diepoxybutane (DEB). The knowledge on intraoperative reduction aids and additional tools of enhancing the stability of the reconstruction alleviates a mechanically sound application of antegrade intramedullary nailing in most highly unstable proximal humeral fractures. Oxygen vacancies in the MgO barriers of epitaxial Fe/MgO/Fe magnetic tunnel junctions are observed to introduce symmetry-breaking scatterings and hence open up channels for noncoherent tunneling processes that follow the normal WKB approximation. There is a correlation between the response to MP and the nature of various cells populations and, on the other hand, the type of infiltration. The iodophor film was as effective as the five-minute iodophor scrub followed by an iodophor wash, as determined by a reduction in skin bacterial counts.

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PMSG failed to stimulate follicular growth, and concentrations of follicle stimulating hormone (FSH), E2 and LH were not detectable. A systematic review and meta-analysis of randomised controlled trials was undertaken. Spatiotemporal Chaos Induces Extreme Events in an Extended Microcavity Laser. This MIIP-promoted EGFR protein degradation was reversed by proteasome and lysosome inhibitors, suggesting the involvement of both proteasomal and lysosomal pathways in this degradation. Nearly simultaneously, the Fermi and INTEGRAL telescopes detected a gamma-ray transient, GRB 170817A. The C-terminal domain contains an invariant Q.RSADE.T.F motif shared with the TFIIS elongation factor of RNA polymerase II and its archaeal counterpart. Granuloma annulare and necrobiosis lipoidica with sequential occurrence in a patient: report and review of literature. The CAST (Childhood Asperger Syndrome Test): preliminary development of a UK screen for mainstream primary-school-age children. In model-based clustering based on normal-mixture models, a few outlying observations can influence the cluster structure and number. Pure, powdered and concentrated grape juices showed similar loss of enamel structure to the Cola soft drink.

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Two temporally and functionally distinct response patterns were detected in the superior temporal lobe. Adjusting the QRS Duration by Body Mass Index for Prediction of Response to Cardiac Resynchronization Therapy: Does One QRS Size Fit All?. SLMTA implementation followed the standard three-workshop series, mentorship site visits and audits. Studying survivors of nearly lethal suicide attempts: an important strategy in suicide research. Recently, clinical attention has focused on new methods of reducing treatment time. It was not possible to pool the data because of heterogeneity in the study design, the methods, and the definitions of IPV and infertility/subfertility found across the studies.

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Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial. Radiation therapy with 8 Gy and 16 Gy, without showing any difference in efficacy, resulted in a near stabilization of the BCVA in patients with subfoveal classic or occult CNV in ARMD. Tissue was analyzed at the injury site and in the corresponding L4 and L5 dorsal root ganglia (DRG) throughout the time-course of the neuropathy. New mononuclear, cyclic tetranuclear, and 1-D helical-chain Cu(II) complexes formed by metal-assisted hydrolysis of 3,6-di-2-pyridyl-1,2,4,5-tetrazine (DPTZ): crystal structures and magnetic properties. Critically ill children have low plasma zinc (pZn), correlating with organ failure. High-throughput sequencing enables high-resolution genotyping of extremely duplicated genes. Pancreatic beta cells tenormin tablet uses in urdu sense changes in nutrients during the cycles of fasting and feeding and release insulin accordingly to maintain glucose homeostasis. Collection of the FP samples by finger prick is more acceptable and requires less expertise than venepuncture. Choline esterase activity was measured post mortem in three areas of the brain, both in the absence and presence of TEPP, a specific butylcholine esterase inhibitor, and was found to be significantly reduced in the striatum with both doses and also in the hippocampus at the higher dose.

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Variants shared between both individuals were analyzed for their potential deleterious nature and a low frequency in the general population. Pathology of mitochondria in MELAS syndrome: an ultrastructural study. Vitamin D Control of Hematopoietic Cell Differentiation and Leukemia. Our capability to discriminate object compliance is based on cues both tactile and proprioceptive, in addition to visual. Perceptual gating, stimulus-driven attention selection and resource allocation processes were more pronounced in ADHD-C, are related to activation differences in parieto-occipital networks and suggest attentional filtering deficits. In cancer screening, overdiagnosed cancers are those that did not need to be found because they would not have produced symptoms or led to premature death. Since there are no existing safe and effective treatments of radiation injury, studies of essential metalloelement chelates and combinations of them, as well as combinations of them with existing radioprotectant aminothiols, Ca-channel blockers, acyl Melatonin homologs, substituted anilines, and curcumin as radioprotectants seem worthwhile. By pulse-chase analysis, we show that the biosynthesis of the 450-kDa glycoprotein proceeded through intermediates of 220, 200, and 500 kDa which became perceptible after 1, 4, and 30 min, respectively. Overload or muscle contractions can induce a transient increase in muscle IL-6 and LIF expression, which has a regulatory role in muscle hypertrophy.

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The N-terminally truncated IRAK protein expressed in human monocytic THP-1 cells remains stable upon LPS challenge. Therapeutic control of LDL-C is clearly related to the intensity of lipid lowering drug regimen after the CHD event indicating that a considerable potential still exists throughout Europe to reduce CHD mortality and morbidity rates through more efficient LDL-C lowering. Neither the VDR C352T nor the MPO G463A genotype had manifested association with the dysplasia and carcinoma of the disease, whereas the MTHFR 677TT genotype may be a genetic risk factor for esophageal dysplasia and carcinoma. Prevention and treatment of various infections due to a wide variety of organisms and promoting surgical wound healing are some of the areas where honey is making its mark. A carotid body tumour is a vascular tumour usually located at or around the bifurcation of the carotid artery and originating from the tunica adventitia. Spindle dynamics drives chromosome movement and mitotic progression during mitosis. This could affect spatial variation in healthcare and social customs relating to death and dying. New approaches, findings, and diagnostics in medical and surgical retina.

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Urinary kallikrein in normotensive subjects and in patients with essential hypertension. Mutations in the gene encoding 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC), a bifunctional enzyme that catalyzes the final 2 steps of the purine de novo biosynthetic pathway, were identified in a subject referred for radiation sensitivity testing. Whilst the discourse of palliative care in HIV management is largely documented and regarded as being an essential component, various authors have further argued that within the context of HIV care in sub-Saharan Africa, palliative care and exploration of the dimensions thereof is largely lacking. Summary: Panmyelopathy: a disease picture with heterogeneous pathogenesis. No single histopathological feature of submucosal invasive colorectal cancer (T1-CRC) can reliably predict the risk for lymph node metastasis (LNM). Analyses of the promoter region revealed that an E-box located at -47/-52 is necessary for CEL expression. rudolfensis, the mandibles D211 and D2735 from Dmanisi, and most of the early Pleistocene mandibles from Sangiran. Mutations in the quinolone resistance determining region conferring resistance to fluoroquinolones in Mycoplasma agalactiae. The results showed that the expressions of CXCR3 and CXCL10 were gradually increased in parallel with repeated morphine administration and activation of microglia.

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on treadmill exercise testing) in patients with chronic coronary artery disease (CAD). Mortality data from 22 cancer registries during 2000-2011 were used to analyze the mortality trend, and data from 17 cancer registries during 2003-2005 were used for survival analysis. The ACE insertion/deletion (I/D) genotypes were assessed by the restriction fragment length polymorphism (RFLP) technique. Effects of Fluoxetine on Neural Functional Prognosis after Ischemic Stroke: A Randomized Controlled Study in China. Immunohistochemical evidence for the presence of melatonin in the pineal gland, the retina and the Harderian gland. The main identified predisposing factor for coronary spasm was vasospastic angina and adenosine acted as a can i take zyrtec with high blood pressure medicine revealing factor of this unsuspected diagnosis. Tyrosine hydroxylase (TH) staining of the striatum and substantia nigra pars compacta revealed that edaravone might exert neuroprotective effects on nigrostriatal dopaminergic systems. Biological evaluation of BMS-351 at a dose of 1.5 mg in castrated cynomolgus monkeys revealed a remarkable reduction in testosterone levels with minimal glucocorticoid and mineralcorticoid perturbation. Several lines of evidence indicate that it depends on cell contact, in particular, the activity of aldehyde-fixed infected cells. thuringiensis in plant disease control and its favorable application prospects.

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