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Biofen (Fexofenadine)

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Biofen is an effective medical drug for allergy caused by chemical histamine which is formed in our body naturally and reacts to the external irritants causing the allergic reaction. Biofen blocks the production and increased activity of histamine receptors as a result of which there is a reduction of the response reaction to the external irritants and the main symptoms of allergy are reduced. This drug helps to reduce cold, lacrimation, sneezing, itching, edema and other allergic symptoms.

Other names for this medication:
Afexdine, Alafex, Alernex, Alfexo, Allermax, Altiva, Arogra, Exfen, Fegix, Fenax, Fendosh, Fexigra, Fexodin, Fexodine, Fexofast, Fexohist, Fexona, Fexopark, Fexopride, Fexoquin, Fexoquit, Fexor, Fexotrol, Fexova, Fexozide, Fextral, Histagra, Histakind, Histaloc, Infexo, Intrafen, Jorifex, Monhale, Monten, Nexofex, Odifex, Oregra, Rafen, Rexhist, Xdine, Zegra, Zllerfax

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Also known as: Fexofenadine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain fexofenadine. It may not be specific to Biofen ODT. Please read with care.

You should always take this medicine with water. Do not take it with juice such as grapefruit, orange, or apple juice .

You should NOT take antacids that contain aluminum or magnesium hydroxide within 15 minutes of taking this medicine. If you are uncertain about this, ask your doctor or pharmacist .

For patients using the oral disintegrating tablet form of this medicine:

Make sure your hands are dry. Do not push the tablet through the foil backing of the package. Instead, gently peel back the foil backing and remove the tablet. Immediately place the tablet on top of the tongue. Do not chew or break the tablet. The tablet will dissolve in seconds, and you may swallow it with your saliva. You may drink a glass of water after the tablet has dissolved. Always take this tablet on an empty stomach .

Shake the oral liquid well before using it. Measure the liquid with a marked measuring spoon, oral syringe, or medicine cup .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For symptoms of hay fever: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 6 to 11 years of age—30 mg two times a day. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (disintegrating tablets): Children 6 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor .

For symptoms of chronic hives: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 4 to 11 years of age—30 mg two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (disintegrating tablets): Children 4 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children 6 months to 4 years of age—15 mg or 2.5 mL two times a day. Children younger than 6 months of age—Use and dose must be determined by your doctor .


If you overdose Generic Biofen and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Biofen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Very young children are usually more sensitive to the effects of this medicine. Before giving any of these combination medicines to a child, check the package label very carefully. Some of these medicines are too strong for use in children. If you are not certain whether a specific product can be given to a child, or if you have any questions about the amount to give, check with your health care professional, especially if it contains:

Antihistamines—Nightmares, unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in children taking antihistamines. Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Increases in blood pressure may be more likely to occur in children taking decongestants. Iodides (e.g., calcium iodide and iodinated glycerol)—These medicines pass into the breast milk and may cause unwanted effects, such as underactive thyroid, in the baby. Narcotic antitussives (e.g., codeine, dihydrocodeine, hydrocodone, and hydromorphone)—Breathing problems may be especially likely to occur in children younger than 2 years of age taking narcotic antitussives. Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines. Salicylates (e.g., aspirin)—Do not give medicines containing aspirin or other salicylates to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor. This is very important because salicylates may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Also, children may be more sensitive to the aspirin or other salicylates contained in some of these medicines, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

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This article, the first in a series, reviews some well-known difficulties involved in the assessment and evaluation of elderly patients. Perceived support needs of family caregivers and implications for a telephone support service. Using a Checklist to Improve Family Communication in Trauma Care. More Than a Tick Box: Medical Checklist Development, Design, and Use. reported specific regression formulae for dental age calculation. In Situ Generation of Quinolinium Ylides from Diazo Compounds: Copper-Catalyzed Synthesis of Indolizine.

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Branchial pouch-derived anomalies may arise from remnants of the first, second, or third/fourth branchial arches. We will review the challenges that hindered the natural variation studies in Neurospora, and how they were overcome. Several strategies have been used to delay the availability of affordable generic drugs into the United States and world markets. Our aim was to assess the heterogeneity of high-risk (HR) prostate cancer managed with high-dose external beam radiotherapy (EBRT) with androgen deprivation therapy (ADT). The most likely As(V)-MnO2 complex is a bidentate binuclear corner sharing (bridged) complex occurring at MnO2 crystallite edges and interlayer domains. Interferon-gamma and granulocyte-macrophage colony stimulating factor therapy in three patients with pulmonary aspergillosis. Patients with severe acute respiratory distress syndrome (ARDS) and hypercapnia present a formidable treatment challenge.

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Sensitivity of acatalasemic mice to acute and chronic irradiation and related conditions. All of these provide more opportunity for effective utilization of this green surfactant. Various products made with or containing formaldehyde are listed in a table. Whilst the physiological relevance of this interaction has yet to be elucidated, these data raise the intriguing possibility that fat loss seen in laminopathies may be caused, at least in part catapres 100 mg , by reduced binding of the adipocyte differentiation factor SREBP1 to lamin A. The zygomatic implant is suggested to be placed in zygomatic areas with the largest thickness, but regions to obtain the largest bone-to-implant contact (BIC) were unknown.

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The lower pulmonary vascular resistance in steroid patients resulted in a higher pulmonary capillary flow which however went to non- or poorly ventilated parts of the lung, seen as an increased intrapulmonary shunt. Current research is focused on whether this is the case, and on linear and nonlinear techniques, both optical and electronic, to understand, unlock and maximize the capacity of optical communications in the nonlinear regime. Detection of alpha, beta, and gamma change in assessments of organizational intervention have been problematic because of lack of clear definition of beta and gamma change and/or methods to assess such change. A case of fingertip avulsion injury with loss of the nail plate, nail bed, and periosteum over the exposed distal phalanx of the thumb was reconstructed by a split-thickness nail bed graft placed directly on granulating decorticated bone. Twenty-five obese adolescents who participated in a 19-day summer camp-based immersion treatment (IT) program completed pre-intervention measures of sleep duration and quality, and pre- and post-intervention body mass index z-scores (zBMI) and waist circumference (WC) assessments. Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion. Successful removal of the offending cTDH was achieved in all patients.

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All emergency department visits among females aged 15-44 years with an International Classification of Diseases, ninth revision, Clinical Modification diagnosis code indicating pelvic inflammatory disease during 2006-2013 were assessed from robaxin max dose daily the HealthCare Utilization Project Nationwide Emergency Department Sample. The gene is known to be associated with cognitive deficit phenotypes within schizophrenia. Cell apoptosis and cell cycle assay were used to assess the effect of TopBP1 on apoptosis and cycle of OS cells. By examining nitrate reduction by transformants containing one of the two plasmids, it was found that nitrite accumulation was influenced by the 9.0-kb plasmid, designated as pYR1. Time-intensity curves were created, and perfusion parameters were calculated by off-line software. Low renal perfusion pressure (50 mmHg) and isoprenaline (2.43 muM) stimulated renin release in perfusion experiments with both 20 and 60 g/l., but the rate of renin release was substantially greater with 60 g/l.7.

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We followed-up 325 patients from 3 English health districts approximately 6 years after TKA, along with 363 controls selected from the general population. Emerging studies have shown that the transcriptional activity of HIF is highly regulated at multiple levels and the epigenetic regulators are essential for HIF-mediated transactivation. On sufficient statistics of least-squares superposition of vector sets. Comparison of functional outcome of bipolar hip arthroplasty and total hip replacement in displaced femoral neck fractures in elderly in a tenormin dosage form developing country: a 2-year prospective study. Effect of total body irradiation dose escalation on outcome following T-cell-depleted allogeneic bone marrow transplantation. The most caudal region, Tm plus Tp, received inputs from the large visual pulvinar of squirrels, possibly accounting for the sensory architectonic characteristics of this region.

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