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Bionil (Glibenclamide)
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Bionil

Bionil is an inexpensive drug that helps to treat type 2 diabetes. It is slightly less popular than comparable drugs. Bionil is only available as a generic drug; all brands have been discontinued. Bionil is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Afdiex, Betanase, Betrol, Bionil, Combidos, Comdiab, Daocon, Diabetnil, Diabetrol, Diabnil, Diolin, Duotrol, Eumet, Giclamide, Glibet, Glibson, Glifil, Glime, Glimsug, Glinil, Glitrac, Glucomin, Glucored, Glucosafe, Glucosil, Glucotrac, Glutowin, Glybenclamide, Glybid, Glybonil, Glyboral, Glybovin, Glybovine, Glycurb, Glycurub, Glymep, Melitus, Metclam, Monomet, Pionorm, Sugatrol, Sugnil, Sugnl, Sugronil, Sycored, Symet, Triglycomet

Similar Products:
Nimotop, Coreg, Dramamine, Urispas, Sovaldi, Azulfidine, Amoxil, Zithromax

Also known as: Glibenclamide

Description

{name} is used to treat high blood sugar levels caused by type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. {name} belongs to a class of medicines called sulfonylureas. It causes your pancreas to release more insulin into the blood stream. {name}, micronized may be used alone or with another oral medicine such as metformin.

{name}, micronized is available only with your doctor's prescription.

Dosage

Usual Adult Dose for Diabetes Type 2:

Doses provided as Bionil-metformin -As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 1.25 mg-250 mg orally once a day -Consider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucose (FBG) greater than 200 mg/dL or HbA1c greater than 9% Maintenance Dose: Increase in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose: 10 mg-2000 mg per day -Patients with Inadequate Glycemic Control on a Bionil (or another Sulfonylurea) and/or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; 5 mg-500 mg dose should not be used as initial therapy due to an increased risk of hypoglycemia; initial doses should be conservative to avoid hypoglycemia largely due to Bionil and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of Bionil (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Addition of thiazolidinedione may be appropriate for patients not adequately controlled on Bionil-metformin; in patients experiencing hypoglycemia, consider reducing the dose of the Bionil component. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Detailed Bionil/metformin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Bionil dosage information

Side effects

The most common side effects associated with Bionil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to Bionil, micronized or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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In order to explore the relationship of TCM syndrome patterns with the type, degree and characteristics of fatigue, its future application for evaluation of fatigue and intervention effect of anti-fatigue should be combined with TCM syndrome differentiation. The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG. This case series highlights the need for health care providers to have a high index of suspicion so that infants with suggestive symptoms, especially in settings with high Helicobacter pylori colonization prevalence can be evaluated for Helicobacter pylori gastritis infection. Preseasonal intranasal immunotherapy with nebulized short ragweed extract. Ventilatory Efficiency in Children and Adolescents Born Extremely Preterm. Studies on tooth crown size and structure in families and in individuals with various sex chromosome anomalies have demonstrated differential direct effects of the human X and Y chromosome genes on growth. A case of perinephritis with renal artery stenosis and hypertension.

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Although several methods have been developed to address the drug response prediction, there are many challenges in obtaining accurate prediction. DLVO Approximation Methods for Predicting the Attachment of Silver Nanoparticles to Ceramic Membranes. Intraocular pressure on the first postoperative day as a prognostic indicator in phacoemulsification combined with deep sclerectomy. Lymphocyte count or percentage: which can better predict the prognosis of advanced cancer patients following palliative care?. To albenza 200 mg cost establish the effects of the somatostatin analogue lanreotide on exocrine pancreatic secretion. Changing precipitation regimes could have profound influences on carbon (C) cycle in the biosphere. The aim of this study was to undertake a review of ambulatory services provided by the QSCIS (SIU and SPOT) to help identify where telehealth may potentially be useful. The results of this study showed that a legume-enriched diet significantly reduced the hs-CRP concentrations in first-degree relatives of patients with diabetes after 6 wk of intervention compared with a habitual diet. Clinical progress was followed with at-least-weekly blood counts, chemistry profiles, urine analysis, liver function tests and recordings of side effects.

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- To review the normal histologic features of duodenal mucosa and describe the clinical and histologic findings in celiac disease and its mimics, listing the differentiating features of biopsies with villous atrophy and epithelial lymphocytosis. Patients in whom rubber tubes were inserted between the gauze layers of the anterior nasal packs suffered no such inconvenience and showed no such gradients. Participants also reported the likelihood that they would engage in extramarital sex if the opportunity presented itself. Zegerid (on demand immediate-release omeprazole and sodium bicarbonate combination therapy) has demonstrated earlier absorption and more rapid pH change compared with Losec (standard enteric coated omeprazole), suggesting more rapid clinical relief of heartburn. The dnaA gene product is not required during stable chromosome replication in Escherichia coli. A brief review of this rare disease and its pathogenetic mechanisms is presented. Therefore, our results do not support the hypothesis that in patients with narcolepsy type 1 residual orexin levels play a role in the control of nocturnal BP dipping. To further determine the efficacy of low dose methotrexate therapy in adults with new-onset atopic dermatitis or with idiopathic eczema.

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StereoGene: rapid estimation of genome-wide correlation of continuous or interval feature data. There was a wide range of names given to the provision of teams managing crisis for people with dementia, which may reflect the differences in the setup and procedures of the service. The observers were then showed a lateral view of same hip and asked to comment on quality of film and also whether it would change their classification or intended management. The precise mechanisms of the development of TCM are still unknown, but it is widely believed that it is triggered by the catecholamine surge produced in response to stress. Nuclear magnetic resonance of alanine dipeptides in organic solution.

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Cancer genomics: A nucleosome footprint reveals the source of cfDNA. To identify and classify such states, a subsequent quantitative analysis was performed in order to determine specific numerical information related to the above mentioned relationship. The pancreatic origin can be confirmed by careful evaluation of cross sectional imaging. We have used chemical force microscopy to measure the strength of the interactions of single chemical functional groups with the sidewalls of vapour-grown individual single-walled carbon nanotubes. This conditioned response survived subsequent unilateral red nucleus and cerebellar interposed nucleus lesions. To quantify the role of the MCL complex in restraining multiplanar rotatory loads. The purpose of this study was to evaluate pregnancy outcome in a cohort of patients with newly diagnosed undifferentiated connective tissue disease (UCTD). We propose that disruptions in these mechanisms following chronic cocaine use contribute to addiction pathology, in part due to the unique architecture of the mesocortical pathway.

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