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Bitorva (Ezetimibe)
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Bitorva

Bitorva is used together with lifestyle changes (diet, weight-loss, exercise) to reduce the amount of cholesterol (a fat-like substance) and other fatty substances in the blood. It may be used alone or in combination with an HMG-CoA reductase inhibitor (statin). Bitorva is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.

Other names for this medication:
Atofast, Atolife, Atorvik, Avascare, Bitorva, Etimibe, Ezedoc, Ezentia, Ezerem, Ezetib, Ezetimiba, Ezetrol, Ezevas, Ezibloc, Eziwa, Ezzicad, Imbibe, Lipezet, Liponorm, Mactor, Orvas, Razel, Redustat, Statix, Storvas, Tonact, Zeteze, Zetica, Zetimax, Zetivas, Zient, Zivast

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Also known as: Ezetimibe

Description

{name} (ezetimibe) reduces the level of total cholesterol and LDL (bad) cholesterol in the blood.

{name} is used to treat high cholesterol in people who cannot control their cholesterol levels by diet and exercise alone.

{name} works to reduce the amount of cholesterol your body absorbs. You should stay on a cholesterol-lowering diet while taking this medicine.

{name} is sometimes given together with other cholesterol-lowering medications.

Dosage

Usual Adult Dose of Bitorva for Hyperlipidemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Bitorva for Homozygous Familial Hypercholesterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Adult Dose of Bitorva for Sitosterolemia:

10 mg orally once a day Uses: -For use as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin) as an adjunct to diet to reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin to reduce elevated total-C and LDL-C levels in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Hyperlipidemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Homozygous Familial Hypercholesterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Usual Pediatric Dose for Sitosterolemia:

10 years or older: 10 mg orally once a day Uses: -For use as monotherapy or in combination with a statin as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia -For use as combination therapy with a fenofibrate as an adjunct to diet to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with mixed hyperlipidemia -As an adjunct to diet to reduce elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia -For use as combination therapy with atorvastatin or simvastatin for the reduction of elevated total-C and LDL-C in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable

Detailed Bitorva dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bitorva are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Bitorva if you are allergic to Generic Bitorva components. Do not take Generic Bitorva if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Bitorva can ham your baby. Generic Bitorva cannot be taken by children under 10 years. Generic Bitorva cannot be used together with fibrates (such as Lopid, Tricor). Try to be careful using Generic Bitorva if you take cyclosporine (such as Sandimmune, Neoral, Gengraf); another cholesterol "lowering drugs fenofibrate (such as Tricor), (gemfibrozil (such as Lopid), clofibrate (such as Atromid-S), lovastatin (such as Altocor, Mevacor), pravastatin (such as Pravachol), fluvastatin (such as Lescol) or simvastatin (such as Zocor), atorvastatin (such as Lipitor). It can be dangerous to use Generic Bitorva if you suffer from or have a history of liver disease. If you experience drowsiness and dizziness while taking Generic Bitorva you should avoid any activities such as driving or operating machinery. Avoid alcohol. Keep low-cholesterol and low-fat diet. Do not stop taking Generic Bitorva suddenly.

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