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Bludol (Tramadol)

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Bludol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Bludol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Other names for this medication:
Acema, Acupain, Acuvin, Bestodol, Cemadol, Cradol, Dolfre, Inodol, Ivydol, Leedol, Madol, Omodol, Opigesic, Painadol, Painex, Rimol, Sedate, Siatram, Spasteez, Takol, Tradol, Tramadol, Tramaflam, Tramed, Tranzat, Trapain, Trapidol, Vardol, Zamadol, Zotadol

Similar Products:
Requip, Zyvox, Bystolic, Arimidex, Nizoral, Prevacid, Valtrex, Tricor, Sovaldi, Mellaril

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Bludol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Bludol ER.

Never share Bludol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Bludol ER.

Bludol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Bludol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Bludol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Bludol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Bludol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bludol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Significance of blood-related high-risk behaviors and horizontal transmission of hepatitis B virus in Iran. Actions and mechanisms of action of novel analogues of sotalol on guinea-pig and rabbit ventricular cells. In contrast, the integrated GSM may reveal mutant physiologies in diverse bioreactor conditions, leading to the design of robust strains with high chances of success in industrial settings. Seasonal variation of vocal behaviour in a temperate songbird: assessing the effects of laboratory housing on wild-caught, seasonally breeding birds. The paper concludes with an illustrative application of the M-quantile approach, mapping low birth weight incidence data for English Local Authority Districts for the years 2005-2010. Unexpectedly, the density of NKp46 on intrahepatic NK cells varied considerably among individuals, allowing us to demonstrate that HCV reload in the early posttransplant period was delayed in recipients of liver allografts containing a higher proportion of NKp46 NK cells. Serum placental protein 14 (PP14) reflects endometrial status during hormone replacement therapy. We also found that YAP1 knockdown repressed cell proliferation and invasion and promoted apoptosis of EC cell lines. Rat liver dipeptidylpeptidase IV contains competing apical and basolateral targeting information.

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Characterization and developmental expression of chick aortic lysyl oxidase. Network Analysis of Genome-Wide Selective Constraint Reveals a Gene Network Active in Early Fetal Brain Intolerant of Mutation. Phase separation of binary fluids quenched by contact with cold external walls is considered. The usefulness of conducting DNA damage and repair studies in a postmitotic tissue like brain is emphasized. A culture-based approach was used to isolate extracellular polysaccharide (EPS) producing bacterial strains from milled sugarcane stalks. Dissociable neural imprints of perception and grammar in auditory functional imaging. The clinical implications of a smoking ban on submarines in the U.S. The evidence-practice gap in specialist mental healthcare: systematic review and meta-analysis of guideline implementation studies.

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Although results have to be interpreted with caution because of the small sample size, psychiatric symptomatology was significantly different between TLE and FLE. Data concerning patient characteristics, clinical and pathologic tumour characteristics and treatment strategies and their results were obtained from a retrospective review of medical records. The checklists for randomized controlled trials, case-control studies, and cohort-studies provided by the Dutch Institute for Healthcare Improvement and the Dutch Cochrane Centre were used to assess methodological quality. The level of recombinant enzyme in the larval hemolymph at 4 days post-infection (40 micrograms/ml) was more than 100-fold the peak levels found in the culture medium (250 ng/ml). For the plastic flow, no power-law scaling relationship between the average velocity and applied driving force can be derived and history dependence of the depinning occurs. Trends in dementia incidence: Evolution over a 10-year period in France. However, few studies are, to date, focused on rehabilitation strategies that could improve cognition.

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Extracellular Matrix in Atherosclerosis: Hyaluronan and Proteoglycans Insights. The binding properties of two electroactive glutathione-ferrocene conjugates that consist in glutathione attached to one or both of the cyclopentadienyl rings of ferrocene (GSFc and GSFcSG), to Schistosoma japonica glutathione S-transferase (SjGST) were studied by spectroscopy fluorescence, isothermal titration calorimetry (ITC) and differential pulse voltammetry (DPV). To report a case of hypomania induced by transcranial direct current stimulation (tDCS) given with an extracephalic reference electrode. The authors conducted a case-control study to identify early clinical signs of CM in consecutive patients with generalised dystonia. (1) To investigate associations between single nucleotide polymorphisms (SNPs) in osteopontin (OPN) and its receptor-cluster of differentiation 44 (CD44) genes and gastric cancer susceptibility. A series of recent genetic, live imaging and heterochronic parabiosis experiments are providing new insights into the underlying mechanisms of reduced regenerative capacity with aging. lactis but excessive production by BSH of bile acid micelles in the cytoplasm inhibited cell growth.

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A base-promoted, microwave-assisted one-pot tandem reaction from simple 3-(1-alkynyl)chromones with 2-halobenzylic nitriles (esters or amides) for the synthesis of novel functional polycyclic chromenones has been developed. Life of Leaders is a clergy health intervention designed with particular attention to the lifestyle and beliefs of United Methodist clergy, directed by Methodist LeBonheur Healthcare Center of Excellence in Faith and Health. The patient iceberg: some characteristics and variations in consultation behaviour. Due to their error-prone replication, RNA viruses typically exist as a diverse population of closely related genomes, which is considered critical for their fitness and adaptive potential. Such a system was tried at Samaritan Hospital, Troy, NY, with disappointing results.

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Using a brief 10-item generic measure of quality of life in English and Spanish speaking diabetic patients. QRFP also stimulated CRF mRNA levels and CRF promoter activity directly in 4B cells following their transfection with the CRF promoter. Our study presents comprehensive gene expression data of CAL-33 subclones with different radiation sensitivity. This study shows an increase in SES disparities in 6th and 7th graders FV intake from 2001 to 2008, partly mediated by an increasing SES disparity in accessibility and preferences of FV. This is the case of a man who presented to the emergency department with a metallic foreign body lodged in the parotid introduced accidentally as a projectile. The present study addresses the effects of a single acute ethanol exposure on growth-associated protein-43 (GAP-43) and brain-derived neurotrophic factor (BDNF) gene expression in neurons in the cerebellum and hippocampus of adolescent rats. Perioperative antibiotics covering bile contamination may prevent abdominal infectious complications after pancreatoduodenectomy in patients with and without PBD. We followed floppy infants who were pointed out as showing motor delay on health examinations at 4 or 9 months of age until at least 2 years of age. Time to connect: bringing social context into addiction neuroscience. Estimation of Duloxetine Hydrochloride in Pharmaceutical Formulations by RP-HPLC Method.

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We have transfected the human IFN-beta gene into primary splenocytes from mice regulated by the If-1 locus and have shown that the exogenous gene is regulated by this locus in a manner similar to that of endogenous IFN genes. Multi-slice computed tomography was employed to visualize the coronary artery system. Craniocervical dissociation is a rare but serious condition, and missed injuries have been associated with poor neurologic outcomes and deterioration. Content validity was assessed by 18 Indonesian experts on July 2012. In positive-stranded RNA viruses, helical capsids are typically composed of many identical subunits of the viral capsid protein (CP), encapsidating a molecule of viral genomic RNA. Nutrition and cardiovascular health: 2015 American Dietary Guidelines Advisory Report. A case of para que es el neurontin de 300 mg hepatitis in a patient receiving rituximab for ITP is reported. Second messengers and membrane trafficking direct and organize growth cone steering.

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