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Bupropion helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Rulide, Zithromax, Keflex, Sporanox, Amethopterin, Imovane, Remeron


{name} SR is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Too much of this medicine can increase your risk of a seizure.

You may take Bupropion XL with or without food.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

You should not change your dose or stop using Bupropion XL suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the first 2 weeks of treatment. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.

Your doctor may prescribe a nicotine replacement product (such as patches or gum) to help you stop smoking. Start using the nicotine replacement product on the same day you stop (quit) smoking or using tobacco products.

Some people taking Bupropion XL (Bupropion or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with this medicine.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may have nicotine withdrawal symptoms when you stop smoking, including: increased appetite, weight gain, trouble sleeping, trouble concentrating, slower heart rate, having the urge to smoke, and feeling anxious, restless, depressed, angry, frustrated, or irritated. These symptoms may occur with or without using medication such as Zyban.

Smoking cessation may also cause new or worsening mental health problems, such as depression.

This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Bupropion XL.

Store at room temperature away from moisture, heat, and light.

Detailed Bupropion XL dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Bupropion SR can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Bupropion are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Bupropion XL if you are allergic to it, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take Bupropion XL. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Bupropion XL to treat more than one condition at a time. If you take this medicine for depression, do not also take Bupropion XL to quit smoking.

Bupropion XL may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

Tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); depression, bipolar disorder, or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking this medicine if you are pregnant. It is not known whether Bupropion XL will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Bupropion XL is not approved for use by anyone younger than 18 years old.

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The UV-mediated induction of recA and sfiA genes in Escherichia coli cells with distinct levels of dATP has been studied. Surface electromyography (sEMG) from the trapezius, anterior deltoid, biceps brachii, wrist flexors, and wrist extensors muscles of 26 dairy workers were used to create muscle activity profiles for the milking tasks common in large-herd dairy parlors. The rat lung-worm Angiostrongylus cantonensis: a first report in South Africa. From these data we have evidence that these methods reliably detect oculomotor deficits in the concussed group, including reduced spatial accuracy and diminished tracking performance during visually guided prosaccade and self-paced saccade tasks. The (31)P NMR spectra of the degraded olive oils, which contain OH groups derivatised with a phosphorus reagent, showed that conventional heating is more detrimental to the oil than microwave technique.

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A cholesterol-binding domain in STIM1 modulates STIM1-Orai1 physical and functional interactions. At 1 year, the reduced full-field ERGs were almost normal size and the multifocal ERGs in the area corresponding to the enlarged blind spot were also improved. Two different foam control strategies have thus been implemented: a classical chemical foam control strategy and a mechanical foam control (MFM) based on the Stirring As Foam Disruption principle. An experimental radiologic reporting system has been developed and tested. Gastrointestinal bleeding is a well-known risk of systemic anticoagulation. Evaluation of sulphasalazine in the treatment of spondyloarthropathies. A 38-year-old man was admitted with persistent productive cough and right anterior chest pain. In this study, for the first time in cattle in the region of Adana serological methods revealed the presence L.

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The replication of viral nucleic acids triggers cellular antiviral responses. The galactosyl transfer reaction to branched cyclodextrins (CDs) was investigated using lactose as a donor substrate and branched CDs as acceptors by various beta-galactosidases. However, the penetration of targeted nanoparticles deep into tissue can be hindered by their slow diffusion and a high binding affinity. Here, we show how monodisperse colloidal octapod-shaped nanocrystals self-assemble, in a suitable solution environment, on two sequential levels. This paper is focused on the fundamental mechanism(s) of viscoelastic turbulence that leads to polymer-induced turbulent drag reduction phenomenon.

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Variants in the Toll-interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population. Treatment options for patients with higher-risk MDS include hypomethylating agents (azacitidine and decitabine), intensive chemotherapy (ICT), and allogeneic stem-cell transplantation (alloSCT). Parent and family impact of raising a child with perinatal stroke. Type IV pili (T4P) are among the key virulence factors used by P. Correlative Analysis of miRNA Expression and Oncotype Dx Recurrence Score in Estrogen Receptor Positive Breast Carcinomas. The multivariate analysis revealed that middle-aged participants were less likely to be happy than younger and older participants, and higher happiness was associated with being part of a couple, higher income, lower stress, healthy diet, exercise, and certain exercise environments (e.g., mountain trails). A case of chloroquine-induced cardiomyopathy that presented as sick sinus syndrome. Delivery of transcriptional factors may affect genome stability, while small-molecule compounds may require more evaluations when applied in vivo. Statistical experimental designs were applied to the execution of process characterization studies evaluating the impact of operating parameters on product quality attributes and process performance parameters.

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In this review, we describe progress since then in gene therapy. The classification of pollen species and types is an important task in many areas like forensic palynology, archaeological palynology and melissopalynology. We found that changes in intensity along the positive slope of the rate-level function (RLF) evoked changes in spectrotemporal filtering that influenced the overall timing of spike events but preserved their precision across trials such that the decoding of single neuron responses was not affected. Acoustic detection of cracks in the anvil of a large-volume cubic high-pressure apparatus. These effects of Tra do not require its only known targets doublesex and fruitless. The potential for sexual transmission to compromise control of Ebola virus outbreaks. MRI has potential for monitoring interstitial laser surgery or hyperthermia. Age-dependent mesial temporal lobe lateralization in language fMRI. Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback. Interdisciplinary approaches to those tumors more frequently encountered in the pediatric population in these locations are discussed.

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Reply to comment on Agarwal et al.: Does initial Pirani score and age influence number of Ponseti casts in children?. Clinicopathological data were prospectively collected from patients undergoing surgery for gastric cancer who presented to the National University Hospital between 2000 and 2005. Intravenous leiomyomatosis is an example of unusual growth patterns that is sometimes exhibited by uterine leiomyomas, characterized by smooth muscle proliferations within the uterine or pelvic veins. In these animals, last seven amino acids of GluR2 or GluR3 subunit, the binding sites of interacting protein, are deleted in vivo. In conclusion, bortezomib sensitized HCC cells to CS-1008 through the inhibition of CIP2A. The synthesis of new xylosyloligosaccharides by transxylosylation with Aspergillus niger beta-xylosidase. To describe an anchoring technique using a balloon protection device that provides excellent stability of the guiding catheter. Immunohistochemistry performed on either fetal (day 19) or newborn (less than 15h after birth) ovaries showed the presence of catecholaminergic nerves, identified by their content of immunoreactive tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis. These genetic alterations in the commercial cell lines have been attributed to several factors, the most common being immortalization.

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Free-energy landscapes from adaptively biased methods: application to quantum systems. Stage-stratified RS rates were calculated with multiple factors assessed for significance. Premotor area F5 acted as a hub that shared the visual coding of AIP only temporarily and switched to highly dominant motor signals towards movement planning and execution. Ethanol or methanol extracts of 68 edible Korean native plants were screened to find effective natural plant sources for the treatment of GIO, and Poncirus trifoliata (L.) (Rutaceae, PT) was selected as a final candidate because of its high inhibitory activity plus its novelty. There was also a greater voltage dependence to the galanin-induced submandibular response than to the sublingual response. The accumulation of 5-HT (after inhibition of monoamine oxidase) and the rate of synthesis of 5-HT in the whole brain (minus cerebellum) were enhanced by dietary and intraperitoneal administration of RbCl, respectively.

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Social dynamics of mammals: Reproductive success, kinship and individual fitness. To assess pharmacodynamic and safety profiles of ONO-9054 following single and multiple day dosing in subjects with ocular hypertension or open-angle glaucoma. The topical latanoprost widened the ciliary cleft despite the narrowing of the ICA and CC entry. The present method can also be used for the monitoring of other homogenous and heterogeneous reactions in liquid phases, which will show potentials in the catalysis industry. Here, we utilized the lethal enterocolitis model in Syrian golden hamsters to analyze the microbiota disruption and recovery along a 20-day period following a single dose of clindamycin on day 0, inducing in vivo susceptibility to C. We conducted an age-period-cohort analysis using data from the US Vital Statistics and the US Census covering the period 1968-2007. Dual targeting of c-Met/EGFR may have clinical benefit for lung cancer.

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GLM is able to classify patients with LM-CRC into three independent groups and offers reliable information for predicting postoperative death in such patients. Papillary carcinoma of the thyroid is the commonest type of thyroid cancer. The authors developed a new surgical procedure for use in treating pure cyclodeviation. Shortage of glucose in the brain, or neuroglycopenia, results in a gradual loss of cognitive functions causing slower reaction time, blurred speech, loss of consciousness, seizures, and ultimately death, as the hypoglycemia progresses. While seeking to overcome these limitations, we discovered that Vaccinia virus has the innate ability to transfer exogenous plasmid DNA into mammalian cells during the infection process.

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ADSCs were isolated from rat adipose tissue and then induced to initiate neural differentiation. Geographic distribution of need and access to health care in rural population: an ecological study in Iran. To explore the bidirectional relationship between the development of rheumatoid arthritis (RA) and atherosclerosis using bovine type II collagen (CII)-immunized B10.RIII apoE(-/-) mice, a murine model of spontaneous atherosclerosis and collagen-induced arthritis (CIA). There have been no cases of recurrence and a limited operation, such as distal esophagectomy, was able to be performed in albenza 200 mg over the counter purchase six. Muscle cells C2C12 and liver cells HepG2 were used to test the effect of Met-Leu on Sirt1 activation.

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The role of CD23 and its receptor in T-cell/B-cell interaction: implications for regulation of IgE synthesis. World Brain Day 2016: celebrating brain health in an ageing population. Giant atrial myxoma mimicking severe mitral stenosis in young patient. Given the toxicity of cytotoxic agents to humans (not only for patients but also for healthcare professionals), the development of reliable analytical methods to analyse these compounds became necessary. These abnormalities lead to the formation of polyads instead of tetrads at the end of meiosis, and might be responsible for the fertility defects observed in this mutant. Putative biological roles of toxins, based on their channel-forming activity, in the capture and killing of prey, digestion, repelling of predators and intraspecific spatial competition are suggested.

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