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Calchan (Nifedipine)

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Calchan is a dihydropyridine calcium channel blocker. Calchan is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Calchan was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Calchan works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Adefin, Afeditab, Antrolin, Atanaal, Belnif, Calcigard, Cardipin, Cardules, Corinfar, Depine, Emaberin, Jutadilat, Myogard, Nidipine, Nifangin, Nifecor, Nifed, Nifedate, Nifedigel, Nifedine, Nifedipin, Nifedipress, Nifelong, Nifensar, Nifezzard, Nifin, Nilol, Nyefax, Siopelmin, Zenusin

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Cordarone, Xalatan, Eulexin, Reminyl, Aygestin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Calchan. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Calchan and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Calchan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Subtoxic exposure to CPF has long-term adverse effects on synaptic function/development and behavioral performance. GCS silencing or pharmacological GCS inhibition sensitized hepatoma cells to sorafenib exposure. In human fetal testes, adrenodoxin mRNA was more abundant in early gestation, diminishing toward midterm in a pattern closely similar to that we reported previously for P450scc. Functional and in vitro gastric digestibility of the whey protein hydrogel loaded with nanostructured lipid carriers and gelled via citric acid-mediated crosslinking. Flexible parental care: Uniparental incubation in biparentally incubating shorebirds. Efficacy and safety of an adjunctive mGlu2 receptor positive allosteric modulator to a SSRI/SNRI in anxious depression. The Department of Surgery, University of the Orange generic lexapro does not work Free State--the first decade.

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Bioassay-directed identification of organic toxicants in water and sediment of Tai Lake, China. The intellectual disability construct and its relation to human functioning. AcuNav is a unique intracardiac imaging device, which allows comprehensive structural and functional flagyl antibiotic good rx cardiac assessment. Systemic inflammation induced by microRNAs: Endometriosis Derived Alterations in Circulating microRNA 125b-5p and Let7b-5p regulate Macrophage Cytokine Production. To obtain direct evidence of its role in nodule senescence, Agrobacterium rhizogenes-mediated RNA interference was applied to A. Current Controlled Trials ISRCTN37248047 and PROSPERO CRD42013005335. Importantly, for the first time to our knowledge, we were able to perform entirely unsupervised artifact removal, i.e. The addition of lecithin to gelatin and HC ODFs may improve the incorporation and the oral transport of active compounds such as EEP. The Delirium Observation Screening Scale (DOSS) identifies behavioural changes associated delirium onset that nursing staff are uniquely placed to recognise.

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He developed hiccups and nausea, and was diagnosed with hyponatremia (serum Na: 120 mEq/L) on day 6 of the first treatment course. Probiotic prophylaxis to prevent ventilator associated pneumonia (VAP) in children on mechanical ventilation: an open-label randomized controlled trial. Deer are considered important intermediate hosts for the coccidian parasites, Toxoplasma gondii and Neospora caninum. The findings suggest that duphaston 10mg tablet uses in kannada modulation of interhemispheric inhibitory interactions between the contralesional and ipsilesional M1, either primarily or secondary to intrahemispheric excitability changes in either hemisphere, may contribute to performance improvements with cutaneous anesthesia of the intact hand. The molecular mechanisms involved in resistance to 5-fluorouracil (5-FU) in colon cancer patients remain to be elucidated. Here, we present a regional assessment of human marker prevalence among drainages that discharge to the U.S. The peculiar behavior of the glass transition temperature of amorphous drug-polymer films coated on inert sugar spheres. One Health still suffers from a lack of strong environmental stakeholders and has mostly worked on infectious disease rather than addressing many of the pressing determinants of health that will confront us in the next century.

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The results provide novel insights into the mechanisms underlying the epididymal innate immune responses to UPEC infection. Patients with hepatocellular carcinoma (HCC) who undergo liver resection and transplantation are predicted to have a poor outcome if the disease is associated with vascular invasion. However, such a hybrid v/c-myc gene is still several fold less active than the v-mycmc29 oncogene. Variation in cytoskeletal assembly during spreading of progressively subcultivated human embryo fibroblasts (IMR-90). Fruit and vegetable consumption and all-cause mortality: evidence from a large Australian cohort study. It is possible that these problems may be solved in the future by increasing the sensitivity of the test and/or by the use of additional tests. Gel filtration chromatography of the 45,000 x g pellet yielded a single sharp peak of binding activity with an apparent molecular weight of 370,000.

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This article provides a brief historical overview of pulse oximetry development, its principles, advantages and limitations, and the clinical applications in neonatal medicine. 90 probands with a confirmed diagnosis of AF and their 144 first-, second-, and third-degree relatives were examined. Possibilities Beyond Analyses of a Fee-for-Service Database and Clinician Mindset. Participants with chronic/recurrent major depression or dysthymia were recruited from 42 UK general practices and randomised to general practitioner (GP) treatment as usual or nurse intervention over 2 years (the ProCEED trial, trial registration:ISRCTN36610074). The adjusted risk for incident hearing loss decreased over time when all industry sectors were combined. Medical telementoring using an augmented reality transparent display. This study addresses the need to explore low-cost methods to manage diabetic ketosis (DK) and diabetic ketoacidosis (DKA).

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