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Cardiorex (Diltiazem)

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Cardiorex is used to treat high blood pressure (hypertension) and prevent chest pain (angina). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. When used regularly, Cardiorex can decrease the number and severity of episodes of chest pain from angina. It may help increase your ability to exercise.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Coreg, Paxil, Bystolic, Zovirax, Rebetol, Avelox, Cialis, Imdur, Reminyl

Also known as: Diltiazem


Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. It belongs to a group of drugs called calcium channel blocking agents. Diltiazem affects the movement of calcium into the cells of the heart and blood vessels. As a result, the heart beats slower and the blood vessels relax, thus, increasing the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardiorex CD. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardiorex LA dosage information

Side effects

The most common side effects associated with Cardiorex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Cardiorex if you are allergic to diltiazem, or if you have:

a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker); very low blood pressure; or if you have recently had a heart attack and you have a build-up of fluid in your lungs.

To make sure Cardiorex is safe for you, tell your doctor if you have:

kidney disease; liver disease; congestive heart failure; or if you also take digoxin, or a beta blocker (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others).

It is not known whether Cardiorex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Diltiazem can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine.

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Effects of reactive oxygen species on lymphokine-activated killer cells in patients with bladder cancer. These results illuminate the contextual nature and evolution of essential gene functions in human cells. By online learning of window size tuning, the status changes of the materials in blending process were reflected in the calculation of standard deviation in a real-time manner. Prediction of mortality after primary surgery for prostate cancer is important for subsequent treatment plans. Peroxisomes are unique among the organelles of the endomembrane system. The relative contributions of these elements vary with the status of the tissue. The primary end point was the difference in average on-treatment Celiac Disease Gastrointestinal Symptom Rating Scale score. Compartmental analysis model was used, based on the obtained imaging data, to assess the Th-227 uptake.

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Dosimetric characterization of CyberKnife radiosurgical photon beams using polymer gels. A meeting was held in November 1997 to discuss clinical issues related to the classification. The suture was secured to the adjacent dural edge by using aneurysm clips, allowing for easy adjustability of the amount of retraction. Limited studies have explored the relationship between air pollution and rheumatoid arthritis (RA), with the results being somewhat inconsistent. Morphological and thermal studies of chitin-curcumin blends derived polyurethanes. The findings are consistent with other data indicating that intensive endurance training during childhood and adolescence does not influence size attained and rate of growth in stature and body mass. LSG related weight loss decreased CRP and ferritin, likely explained by improvement in inflammatory status.

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Calcific myonecrosis arising in the bilateral deltoid muscles: A case report. Experimental Ultrasound Transmission through Fluid-Solid and Air-Solid Phononic Plates. Effect of routine administration of analgesia on energy expenditure in critically ill patients. Protein disulfide-isomerase (PDI) was the first protein-folding catalyst to be characterized, half a century ago. CARDIOVASCULAR RISK FACTOR CLUSTERING AND CORONARY ARTERY DISEASE : A 4-YEAR FOLLOW UP STUDY OF 257 SERVICE PERSONNEL. Low-stress and high-reflectance Mo/Si multilayers for extreme ultraviolet lithography by magnetron sputtering deposition with bias assistance. Although yeast studies showed that BiP retrieval by the KDEL receptor is not essential in single cells, it is crucial for multicellular organisms, where some essential proteins require retrieval to facilitate folding and maturation.

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Habitual physical activity behavior of patients after primary total hip arthroplasty. Gene expression of human ovarian carcinoma cell lines and epithelial ovarian tumors was examined by oligonucleotide microarray for about 6000 human cDNAs. Genes encoding truncated versions of bovine and chicken gamma interferon genes lacking predicted protease cleavage sites at the C-terminus were constructed and expressed in the yeast Pichia Pastoris. Development and differentiation of operative therapy for urologic patients at St. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit.

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After labeling with sodium pertechnetate Tc 99m and reinjecting the erythrocytes contained in 3 to 6 ml blood, external gamma counting over a fixed site in the calf, both in the recumbent and in the standing posture, showed excessive gravitational pooling of blood in the legs of five patients with orthostatic diastolic hypertension, of four with orthostatic narrowing of the pulse pressure, and of 10 with orthostatic tachycardia alone. This study aims to review the current epidemiology and clinical management of patients with cavernous malformations (CM). The patients younger than 25 years consisted of 19 men and 10 women with an average age of 21.0 years (range, 18 to 24 years). A discussion group on gender equality in academic medicine will be established on an internationally renowned open-research platform. Problems with recognition of illness and in seeking help contribute to DUP, but another major cause of prolonged DUP is delays within secondary mental health services. Tissue culture from the disk space confirmed the diagnosis of vertebral osteomyelitis due to hematogenous spread of M. Here, we investigate whether pERK is a useful biomarker for treating HCC with Sorafenib. In the general anaesthesia group the plasma glucose concentration was significantly higher after the intraoperative glucose load than after the preoperative load. Effect of the cryopreservation on the production of leukocyte migration inhibition factor (LIF) by lymphocytes from normal volunteers and patients with laryngeal carcinomas.

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This meta-analysis aims to identify significant risk factors for delayed PPB. Many questions, however, remain unanswered regarding the timing of initiation, optimum doses, need for simultaneous use of RAS inhibitors, and proper monitoring of RAS blockade. Six to twelve months after the surgery, follow-up assessment showed that all patients had recovered functional opposition of the carpometacarpal joint with survival of the skin and a muscle power of M4 to M5. Among cestodes maturing in fishes only one, Parabothriocephalus johnstoni, occurs in a bony fish, Macrourus whitsoni. Hrr25: an emerging major player in selective autophagy regulation in Saccharomyces cerevisiae. Retinal imaging via scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) was also performed to exclude potential morphological alterations. Both in simulations and by reanalyzing a large insect phylotranscriptomic dataset, we show the effectiveness of this simple filtering strategy. The SEM Scanner is a medical device designed for use by healthcare providers as part of pressure ulcer prevention programs. Several mechanisms have been proposed to explain biofilms drug resistance.

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Effect of aminophylline on spontaneous and induced ovulation in rats. It allows for numerical simulations of molecules in solution in a model polar solvent. In this paper, we report time curves of changes in plasma PS during 12 weeks of PS intake. Intravenous propofol was non-inferior to CO2 washout for apnea induction in infant olive baboons. In contrast, when to take the second dose of diflucan autoantibody to polyribosomes stains granules aligned in the long axis of well spread embryonic cells, in the direction of actin-containing fibrils, an arrangement that is lost in cells pretreated with the actin filament disrupting drug cytochalasin B. 31P NMR quantitation of the displacement of equilibria of arginine, creatine, pyruvate, and 3-P-glycerate kinase reactions by substitution of sulfur for oxygen in the beta phosphate of ATP. Due to the very short time of response, and unmasking mechanism can be hypothesized for receptor up-regulation, though an increase of protein synthesis cannot be excluded. Brain norepinephrine: enhanced turnover after rubidium treatment. On the other hand, multi-drug-resistant Acinetobacter baumannii causing nosocomial infections with high mortality has been raising serious concerns in medicine.

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Cervical ultrasound and ultrasound-guided fine-needle aspiration biopsy are the most sensitive modalities in detecting locoregional neck recurrence. Eight hundred and ninety-seven engorged females collected indoor resting or in landing catches were released, and 82 were subsequently recaptured. By using a phase-field model, we simulate formation and growth of stripe arrays starting with anisotropic growth of islands under the Ehrlich- para que serve depakote er 500 mg Schwoebel barrier on metal bcc(110) surfaces. The kinetics of serum antibody responses in broiler chickens against Cryptosporidium baileyi were studied. Using calorimetry, and high resolution respirometry coupled with fluorimetry, we report substrate oxidation by mGPDH in permeabilised flight muscles operates, in vitro, at a high flux, even in the absence of ADP. Understanding how different variants of IL23R associate, at varying levels of strength, with contrasting groups of immune-mediated diseases (CD, psoriasis, ankylosing spondylitis, RA) will enhance knowledge on the aetiology of these diseases. We aim to give readers a clear understanding of how molecular imaging can enable noninvasive tracking of cardiac gene transfer and expression.

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Previously, we showed that in rat cortical neurons, chronic donepezil treatment (10 microM, 4 days) up-regulates nicotinic receptors (nAChR) and makes neurons more sensitive to the neuroprotective effect of donepezil. XK469 was also able to block the activation of MEK by serum addition in starved U-937 cells. Reasons given for consulting their GPs included administrative matters, psychological support, reassurance, and advice, but also to a lesser extent, medical management. Recent advantages of serum microRNAs (miRNAs) open a new realm of possibilities for noninvasive diagnosis and prognosis of many cancers. Leptin is an adipocyte-derived hormone that is secreted in correlation with total body lipid stores. S1T cell, a leukemic non-Tax-producing T-cell clone established from an adult T-cell leukemia (ATL) patient, S1TcTax05 and S1TcTax10 clones, transfected with Tax stably expressing cDNA, and S1Tneo, transfected with a neomycin-resistant gene, were examined for Tax-related anticancer drug resistance. Factors affecting patient compliance with anti-tuberculosis chemotherapy using the directly observed treatment, short-course strategy (DOTS).

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The risk and protective factors in smoking behavior and cessation were investigated. The results are compared with these of a control group of healthy persons and patients with non-rheumatic diseases. Responding to refusal of recommended cesarean section: Promoting good parenting. The PubMed, Embase and Cochrane databases were searched for relevant articles published between January 2000 and July 2014. The time from diagnosis of UA-AEDV to delivery, postnatal survival, and developmental prognoses were the primary outcomes. Self-reported baseline questionnaire data (2006-09) were linked to mortality data up to June 2014. The patient survived until the 18th postoperative day, with no evidence of tissue rejection, but he died following ischemic disruption of the bronchial anastomosis.

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Trauma-induced coagulopathy is a primary factor in many trauma-related fatalities. From the combined temporal bone collections of the University of Chicago and the Mayo Clinic, we identified a group of 125 ears from 80 patients, all with confirmed otosclerosis. VP6 genogroup I and genogroup II could be determined tenormin medicine according to the sizes of the amplicons: 380 and 780 bp, respectively. Heart-specific overexpression of (pro)renin receptor induces atrial fibrillation in mice. Pharmacological properties of adicin, Soviet alpha-acetyldigitoxin. The view is expressed that specific host susceptibility is more important in the pathogenesis of allergic bronchopulmonary aspergillosis than environmental factors.

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Detailed investigation of the PfEMP1 binding site on IgM showed that some of the critical amino acids in the IgM Cmu4 domain are equivalent to those regions of IgG and IgA recognized by Fc-binding proteins from bacteria, suggesting that this region of Ig molecules may be of major functional significance in host-microbe interactions. This is a prospective single case series of 39 patients who had suspected intussusception. Comorbidity and use of medication is often greater among people with than without diabetes. Relationship between induction of thymidine kinase and potentiation of growth of H-1 virus by human adenovirus 12. When operational anticipations are violated, experiencing a vehicle as body-extension is negatively correlated with operational effort as indicated by neural activation in the motor system. One population (Physella columbiana) has evolved for 120 years in the presence of heavy metals and one (Lymnaea palustris) has not. The purpose of this prospective 3-year follow-up was to investigate the association of glucose, insulin, and cholesterol levels with peripheral nervous system function in overweight and obese subjects. We find evidence that during prolonged deprivation, a critical transition takes place pushing the system to excessive alcohol consumption. Mobilisation of stored calcium in the neck region of human sperm--a mechanism for regulation of flagellar activity.

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To determine how myxoma virus eliminates human multiple myeloma cells, we queried the apoptotic pathways that were activated after viral infection using immunoblot analysis and other cell biology approaches. It is mainly indicated when the muscle overactivity is diffusely distributed and should be implemented early, to prevent permanent musculoskeletal deformities or contractures. There is an alarming high level of heavy metals toxicity in Egypt that was positively xanax xr pill identification correlated to IUGR. The addition of panitumumab increased toxicity, and had no discernible impact on efficacy. Different approaches have been proposed for the enrichment of fetal nucleated red blood cells (NRBC) from maternal blood as an alternative way to obtain fetal tissue for non-invasive prenatal diagnosis. Sequence analyses of the high-frequency mutation region along E-cadherin exons 7-9 revealed a number sequence alterations in the patient group as a whole, mostly within exon 8. In this paper, Green functions are derived for spontaneous four-wave mixing in the low- and high-gain regimes. The areas of cooperation with the Medical Library Center of New York and the types of programs needed to run the system are explained.

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