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Cardizem (Diltiazem)

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Cardizem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Cardizem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Decadron, Aldara, Singulair, Cymbalta, Depakote

Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardizem LA. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardizem LA dosage information

Side effects

The most common side effects associated with Cardizem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Genome-wide whole exome sequencing was performed on germline and somatic DNA from an 82-year-old woman who had developed a solid pancreatic cancer but did not show characteristic findings of PTEN hamartoma tumor syndromes (PHTS). We describe a case of perforated rectal cancer that became curatively resectable after FOLFOX4 chemotherapy. The development of instruments to classify the consumers correctly is the first stage in the epidemiologic investigation. CYFRA 21-1 as a tumor marker for squamous cell carcinoma of the esophagus. We report on the impact of linkage quality, cohort follow-up, and multisource outcome ascertainment on the incidence proportion of reported maltreatment before age 6 and hazard ratios of selected characteristics that are often available in birth cohort linkage studies of maltreatment. The objective of this study was to investigate whether or not the detection of survivin expression in the peripheral blood could also have significant effects on the clinical outcomes of patients with gastric and colorectal cancer. Taken together, these results provide a detailed picture of the DASA isomerization pathway on a molecular level. Association between a shelter-neuter-return program and cat health at a large municipal animal shelter.

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The efficacy of two lead candidates targeting Pfs25 and Pfs230 antigens to prevent onwards transmission of naturally occurring parasites to a local mosquito strain is assessed using direct membrane feeding assays and murine antibodies in Burkina Faso. Some pharmacological actions of diethyldithiocarbamate on rabbit and rat ileum. In recent years, several medicinal plants have been demonstrated as valuable resources of naturally occurring polysaccharide-polyphenolic conjugates. The survival and body mass of the workers as well as the presence of three symbiotic protists in the hindguts of the workers were then periodically examined. Ocular surface mucosa is the first-line ocular tissue to be exposed to environmental stress. We used histological analysis to rank the injury according to a score dependent on the injury severity and the affected organ. Semiquantitative method of reverse transcriptase polymerase chain reaction (RT-PCR) was used to analyze the expression level of stathmin mRNA, and immunohistochemical staining (frozen section) was used to detect the expressions of stathmin protein, in laryngeal carcinoma tissues and laryngeal normal tissues of 38 cases, respectively. Analyses of deduced amino acid sequence confirmed molecular features of lysosomal cathepsin D and revealed high similarity between the enzymes from Astacidea and Caridea on one side, and the enzymes from Penaeoidea, Anomura, and Brachyura on the other side. One-Year Mixed-Methods Case Study of a Community-Academic Advisory Board Addressing Childhood Obesity. The present work is dedicated to the assessment of the cold thermal strain of human beings working within freezing chambers.

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Furthermore, quantitative measurement of serum cytokine expression is a promising tool for evaluating the effectiveness of additional non-union therapies such as adjunct application of growth factors. Analysis of complications and deaths in aged patients with obstructive jaundice. Variation in single nucleotide polymorphisms (SNPs) has the potential to impact chemotherapy, radiation, and immune responses, leading to different post-HCT survival outcomes. Segmentation of Planar Surfaces from Laser Scanning Data Using the Magnitude of Normal Position Vector for Adaptive Neighborhoods. Clinical diagnostic testing is still in developmental stages, but the hope is to have a reliable and objective diagnostic tool in order to diagnose AD in the earliest stages. detectMITE: A novel approach to detect miniature inverted repeat transposable elements in genomes.

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This article forms part of a symposium on flavivirus drug discovery in the journal Antiviral Research. Cardiovascular diseases (CVDs) are the major health concern and the leading cause of death. Food intake depression and other metabolic effects of tannic acid in the rat. Feeding of Enterococcus faecium NCIMB 10415 Leads to Intestinal miRNA-423-5p-Induced Regulation of Immune-Relevant Genes. Recently, percutaneous valve-in-valve (VIV) placement of transcatheter valves has established itself as a safe and effective alternative to surgical revision. Validating Performance of a Hospital Discharge Planning Decision Tool in Community Hospitals.

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We analyzed eight novel germ cell-specific proteins, providing new and inclusive information about their developmental and cellular characteristics. Comparison of the effectiveness of anginin and stugeron treatment of cerebral arteriosclerosis. The prevalence at birth of congenital malformations in communities near the Hanford site. Long duration was defined as stents retrieved at a minimum of 1 year following a dacryocystorhinostomy. It thereby reveals a need for further adjustment and improvement of current interpretation tools and may point at a possibly crucial role of subtype-specific information. Effects of a Glutamine Enema on Anastomotic Healing in an Animal Colon Anastomosis Model.

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High rates and low volumes in mechanical ventilation--not just a matter of ventilatory frequency. The limitations of adaptive speech tests as outcome measures in the evaluation of hearing-device features have been discussed. PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling. Relapses of p-ANCA vasculitis during chronic dialysis treatment are infrequent. Added insulin increased the diabetic lymphocyte blast transformation response to each of the mitogens.

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A number of new functionally substituted 1-acyl-5-hydroxy-4,5-dihydro-1H-pyrazoles have been prepared in moderate to excellent yields from the corresponding 2-alkyn-1-ones. The most potential compounds were those with two hydroxy groups and accommodated by binding pocket in S configuration with phenolic group at C(16) imitating A ring of estradiol. Prostacyclin synthesis in brain is localized in cerebral blood vessels and capillaries. However, MSC isolation and expansion are typically performed on super-physiologically stiff tissue culture plastic (TCP), which may alter their behavior and lead to unintended consequences upon implantation. The identification of dengue virus serotypes through molecular and phylogenetic analysis is essential for predicting disease severity or fatal illness, principally in endemic countries such as Brazil. Only one case of association of BWS with Chiari I malformation has been previously reported in the literature.

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Patient was managed conservatively with supportive measures, mechanical ventilation, IV fluids, inotropic agents, steroids, antibiotics and Prazocin. Optical sensing of anticoagulation status: Towards point-of-care coagulation testing. A report on very low level polonium determination in airborne dusts by electrochemical displacement. The susceptibility what schedule drug is xanax to infection correlated with the amount and duration of the IgM response. Sequential targeting of RAF, MEK, or ERK in BRAF-mutant PDXs promotes BRAF amplification and resistance. Pretreatment with various doses of testosterone propionate for 7 days enhanced phalloidin-induced PHLL. In general, evidence to date suggests that spastic cerebral-palsied children show significant improvement in visuomotor and visual perceptual performance with the color-reversal of the standard black-on-white figure-ground relationship in stimulus and response materials of standardized tests. Given the low immunogenicity of this hormone, the use of adjuvants becomes necessary.

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Axonal conduction velocity and force of single human motor units. While most studies in humans have focused on the effects of anabolic hormones on muscle growth, few have considered the impact these hormones have on the motoric system. Demographic characteristics, child nutrition and health status, and maternal and household information were collected. Superior orbital fissure was minimally widened without prolapse of any intracranial contents. Crystallographic studies on the aspartyl-tRNA synthetase-tRNAAsp system from yeast. Rapid-flow regional perfusion is the vehicle used for administration of streptokinase and probably represents the third arm of this therapeutic approach by adding a hemodynamic wash-out effect. High purification of the RNase inhibitor from rat liver by affinity chromatography. Hesperidin Attenuates Ultraviolet B-Induced Apoptosis by Mitigating Oxidative Stress in Human Keratinocytes.

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On the low-temperature fluorescence what drugs should not be taken with zyrtec spectra of blue-green and red algae. The SILAC-mouse approach is a versatile tool by which to quantitatively compare proteomes from knockout mice and thereby determine protein functions under complex in vivo conditions. The use of cutting current for electrosurgical excision is a valuable procedure for the cutaneous surgeon. Using the zebrafish model, we tested the effect of transient developmental exposure to a known anti-estrogenic EDC on adult visually-guided behavior. Dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter 2 inhibitors, and glucagon-like peptide-1 receptor agonists have demonstrated significant improvements in measures such as the mean amplitude of glucose excursions and standard deviation of CGM. Salt stress disturbs cellular environment leading to protein misfolding, affecting normal plant growth and causing agricultural losses worldwide. Wavefront direction and cycle length affect left atrial electrogram amplitude. The effects of increased numbers of carcinogenic treatments on the induction of cervico-vaginal and vulval tumours in intact and castrate rats. thaliana MgCh has been substantially elucidated, different reports provide inconsistent results with regard to the function of CHLI2 in Mg chelation and retrograde signaling. Thus, phosphorylation of PRL by gamma-PAK in granules produces the PRL molecule that has been shown to antagonize the growth-promoting activity of unmodified PRL, and is consistent with the identified role of gamma-PAK in the induction and maintenance of cytostasis.

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Neural basis for spatial memory in animals: what do hippocampal neurons tell us?. Matching of HL-A-DR antigens is relevant for the outcome of cadaver kidney grafts, if donor and recipient share one increasing dose of lexapro side effects DR antigen and two or more HL-A-AB antigens. The surface and mechanical properties were evaluated to validate its properties to the native vessel. CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling. The results of previous studies from our laboratory have shown that neurotensin can stimulate pancreatic secretion of bicarbonate and protein. The projections are based on the initial parameterization of the model and on prevention objectives related to smoking behavior established by the National Cancer Institute.

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A bacteriocin-like peptide induces bacteriocin synthesis in Lactobacillus plantarum C11. A clinical study of the composite/bonding resin-tooth interface. Viro-immune therapy: A new strategy for treatment of pancreatic cancer. Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins. To study the clinical effect and mechanism of Eryanling (EYL) oral liquid in treating acute catarrhal otitis media (ACOM). Most of the clinical sequelae of CV disease events are the result of inflammatory changes at the vascular level.

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Radical perineal prostatectomy for carcinoma of the prbstate: survival in 143 cases treated from 1935 to 1958. Estimates of left ventricular interstitial fluid adenosine during catecholamine stimulation. The development of enhanced recovery after surgery (ERAS) protocols for patients undergoing radical cystectomy (RC) represents a significant advance in perioperative care. Transmitters at chemical synapses are either small molecules or neuropeptides. The Gcn2 kinase is best known as a regulator of translation initiation in response to starvation for amino acids. These cellular states include normal functioning state, adaptive and stressed states at mild to intermediate exposures, and overt toxicity in the presence of an prometrium overwhelming concentration of stressors. Further study is warranted to assess definitive anatomic and functional outcomes resulting from this new technique.

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Structural characterizations of fusion peptide analogs of influenza virus hemagglutinin. The influence of antirheumatic drugs on the occurrence of peptic ulcers. Rhamnazin, a novel inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy. These services are being implemented with expanding geographic scope. Comparison of postoperative refractive outcome in phacotrabeculectomy and phacoemulsification. Total alkaline phosphatase (ALP) activity analysis showed a statistically higher activity of the TPS in mineralization medium compared to the controls.

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Interferon-gamma (IFN gamma) and TNFalpha synergistically induce pancreatic beta-cell apoptosis. A 71-year-old man had an intramural tumour of the middle third of the oesophagus. Complete Genome Sequence of Peste des Petits Ruminants Virus from Georgia, 2016. A hemispherical cardiac phantom was inserted into a cylindrical phantom and both were filled with radioactive 123I water solutions. The comparative risk of adverse events (AEs) with IV iron preparations has been assessed by a few randomized controlled trials, which are most often limited by small patient numbers, which lack statistical power to identify differences in low-frequency AE such as hypersensitivity reactions. Our findings suggest that RF-induced heating is more effective at closing the pancreatic stump than mechanical stapler and leads to the complete atrophy of the distal remnant pancreas. Raman spectra and conformational properties of ribosomes during various stages of disassembly. Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure. Training of postgraduate students has traditionally been done in person in a hospital setting with hands-on training with each faculty member imparting knowledge to 2 to 4 students per year. The purpose of this study was to prospectively evaluate clinical results for open reduction and internal fixation of unstable metaphyseal fractures of the metacarpal and phalangeal bones using a miniature titanium plate.

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To our knowledge, there has been only one other published report of repair of double-outlet left atrium. We explore potential dysregulation of macrophage phenotypes in COPD pathogenesis through integrated study of human small airway tissue, bronchoalveolar lavage (BAL) and an experimental murine model of COPD. An investigation of the relationship between emotional maladjustment and infertility. To examine lexapro and alcohol heart palpitations the effect of anastomosis on experimental carcinogenesis in the colon of rats. We designed a controlled study to evaluate the use of the selective transperitoneal needle aspiration of a bowel loop (STAB) in infants. On the other hand, for the second process, only one state is involved. We included randomised controlled trials evaluating a self-management intervention for people with COPD published since 1995.

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