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Catapres (Clonidine)
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Catapres

Catapres treats high blood pressure by decreasing your heart rate and relaxing the blood vessels so that blood can flow more easily through the body. Catapres extended-release tablets may treat ADHD by affecting the part of the brain that controls attention and impulsivity.

Other names for this medication:
Arkamin, Clodict, Clonidine, Jenloga

Similar Products:
Bystolic, Vasotec, Levlen, Dramamine, Zovirax, Provigil, Mestinon, Rogaine, Levitra

Also known as: Clonidine

Description

Clonidine transdermal is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk for heart attacks. These problems may be less likely to occur if the blood pressure is controlled.

Clonidine belongs to the class of medicines called antihypertensives. It works in the brain to change some of the nerve impulses. As a result, the blood vessels relax and blood passes through them more easily, which lowers blood pressure. When the blood pressure is lowered, the amount of blood and oxygen going to the heart is increased.

This medicine will not cure your high blood pressure, but it does help control it. Therefore, you must continue to use it as directed if you expect to lower your blood pressure and keep it down. You might have to take high blood pressure medicine for the rest of your life.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain clonidine. It may not be specific to Catapres-TTS-2. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To use the skin patch:

Use this medicine exactly as directed by your doctor. It will work only if applied correctly. This medicine usually comes with patient instructions. Read them carefully before applying the patch. Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should. Gently wash the area of skin where you will apply the patch with soap and water. Rinse the skin completely and dry with a clean, dry tissue. Apply the patch right away after removing it from the pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and intact skin area on your upper, outer arm or upper chest. Choose an area with little or no hair that is free of scars, cuts, or irritation. Avoid putting the patch on skin areas where it could be rubbed off by tight clothing. Press the patch firmly in place with your fingertips to make sure that the edges stick well. The patch should stay in place during showering, bathing, or swimming for a full 7 days. If the patch becomes loose, press the edges against the skin and cover the patch with one of the white adhesive covers that are included in the package. Apply a new patch if the first one becomes too loose or falls off. It is best to apply each patch to a different area of the skin to prevent skin irritation.

To help you remember to use your medicine, try to apply the patch at the same time and on the same day of the week.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For high blood pressure: Adults—One patch applied once every 7 days. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath) followed by low blood pressure (feeling light-headed, fainting, drowsiness, cold feeling, slow heart rate, shallow breathing, weakness, or pinpoint pupils).

Storage

Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Detailed Catapres-TTS dosage information

Side effects

The most common side effects associated with Catapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Catapres if you are allergic to clonidine.

To make sure Catapres is safe for you, tell your doctor if you have:

heart disease or severe coronary artery disease; a heart rhythm disorder, slow heartbeats; high or low blood pressure, or a history of fainting spells; a heart attack or stroke; pheochromocytoma (tumor of the adrenal gland); kidney disease; or if you have ever had an allergic reaction to a Catapres TTS patch.

It is not known if clonidine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of clonidine on the baby.

Clonidine may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine.

If you are breastfeeding, tell your doctor if you notice somnolence, tiredness, rapid breathing, and poor feeding in the nursing baby.

Catapres is not approved for use by anyone younger than 18 years old.

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Trends in Drinking Water Nitrate Violations Across the United States. Th9 cells induce steroid-resistant bronchial hyperresponsiveness in mice. Recommendations for funding and new health policy initiatives in the areas of AIDS, maternal and child health, substance abuse, health manpower development, long-term care for the elderly, biomedical research, and national health insurance are presented. Illness severity scores and new diagnostic methods, including procalcitonin, proadrenomedullin, and bacterial diagnostic testing, are being used increasingly for CAP diagnosis. Activities of recombinant collagenases could be detected in collagen zymogram gels copolymerized with 0.3 mg/mL type I collagen extracted from rat tail tendon. During development, microglial progenitor cells migrate into the brain from the periphery, a process critical to the maturation of the developing brain. Inside the vacuole, this substrate is oxidized by MPO released from the azurophilic granules. Indications for surgery include neurologic deficit, instability, as well as malalignment and dislocation. Periostin, a 90 kDa secreted homophilic cell adhesion protein, was recently added to matricellular class of proteins based on its expression pattern and function during development as well as in wound repair.

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To compare outcomes of single-fraction and multi-fraction stereotactic ablative body radiotherapy (SABR) for pulmonary metastases. It is sufficient to control approximately half of the elements to achieve excitable behavior. The innate immune responses were further reduced in Tlr4 and Tlr5 double-knockout EECs. The 131I master solution was then sent by POLATOM to the BIPM International Reference System (SIR). A separate group of animals was administered simvastatin and euthanized at the symptomatic 120-day time-point. The latency of the field potentials evoked by stimulation of quadriceps nerve ranged from 14 to 23 msec in different preparations. Trends in Parent-adolescent Communication in the Czech Republic between 2002 and 2014: Results of the HBSC Study. Volumetric CBCT image-guidance provides sufficient imaging information to reliably predict the need for dose adjustment. This paper first studies the CSS effect on illuminant estimation arising in the inter-dataset-based CC (inter-CC), i.e., training a CC model on one dataset and then testing on another dataset captured by a distinct CSS. The aim of this study was to investigate the SMM rate and the main factors associated with this condition among women living in the Federal District, Brazil.

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Our findings indicate that pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with CAPS and possibly patients with other autoinflammatory diseases. The aim of this study was to evaluate anti-FVIII IgG subclasses in haemophilia A patients with inhibitor both in a cross-sectional and in a longitudinal analysis. Therefore, both human insulins were evaluated in terms of binding to the IGF-1 receptor in chick embryo fibroblasts. The production of Mycoplasma iowae infection of turkey poults suitable for monitoring antimicrobials. Charting a New Path: Helping Local Health Departments Navigate Emerging Issues in Public Health. The need for increased awareness, documentation, and reporting of medication errors throughout the organization was identified as a priority through risk assessment. Potent and selective class IIa HDAC tetrasubstituted cyclopropane hydroxamic acid inhibitors were identified with high oral bioavailability that exhibited good brain and muscle exposure. Telbivudine is an alternative drug of choice for the treatment of hepatitis B patients for whom renal safety is a concern, especially patients with DM and CKD-3. DM appears to be associated with increased metabolic activity in some core area of the default mode network (DMN) and areas connected to the DMN, such as BA 7, hosting sense of self functions. Role of hemoglobin from blood clam Scapharca kagoshimensis beyond oxygen transport.

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Winged scapula incidence and upper limb morbidity after surgery for breast cancer with axillary dissection. These phthalocyanines were converted to their water-soluble quaternized derivatives (3Q-5Q) using excess methyl iodide as a quaternization agent. The p16/miR-217/EGR1 pathway modulates age-related tenogenic differentiation in tendon stem/progenitor cells. These represent new tools that are providing invaluable insights into NIDDM pathogenesis. Whole-brain voxel based morphometry revealed no significant group differences. Hypocalcemia and hypophosphatemia have recently been recognized as common metabolic complications in acutely ill patients. Reasoning Exercises in Assisted Living (REAL): a feasibility study. Incidence of yeasts isolated from the mouth and toothbrushes in Venezuela. A retrospective review of medical examinations for entry to the military service from The Area Military Medical Commission in Lodz.

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The practical benefits of pharmacokinetics in the use of antineoplastic agents. Immunopathogenesis of infection in SPF chicks and commercial broiler chickens of a variant infectious bronchitis virus of economic importance. Older male physicians have lower risk of trochanteric but not cervical hip fractures. This review focuses on factors which may impact nicotine exposure by changing e-cigarette use behavior, puff topography, altering the nicotine yield (amount of nicotine exiting the e-cigarette mouth piece including nicotine exhaled as vapor) or more directly by altering nicotine absorption and bioavailability. Monte Carlo simulations of both designs were performed to determine dimensions for an air cavity to introduce the desired dosimetric correction.

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House-Brackmann facial nerve function evaluation was grade I in all the patients who received examination of facial electroneurography, including stimulation strength, amplitude, and latent time bilaterally. Iatrogenic esophageal perforation in forcing bougienage of its post-burn cicatricial stricture. We review the possibilities and limitations of such a device, termed a visual cortical prosthetic. Case of cholestatic hepatitis with celecoxib did not fulfil international criteria. Safety and Efficacy of Prophylactic Amiodarone in Preventing Early Junctional Ectopic Tachycardia (JET) in Children After Cardiac Surgery and Determination of Its Risk Factor. Synthesis rate of the major muscle contractile protein, myosin heavy chain (MHC), and transcript levels of fast MHC isoforms decrease in association with strength reductions, while mitochondrial protein synthesis rate declines in parallel with activities of mitochondrial enzymes and maximal oxidative capacity (VO2max). Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE. Beta-blockers (BBs) and calcium antagonists (CAs) are reported to aggravate ST-segment elevation in some patients with Brugada syndrome (BrS). To investigate whether multi-layer perceptrons (MLPs) could be used to determine biexponential and diffusional kurtosis model parameters directly from diffusion-weighted images.

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Osteosarcoma is a mesenchymally derived, high-grade bone sarcoma. We reviewed data on inpatient and emergency department visits in NYS with discharge dates from 2005 to 2014 retrospectively. Aeromedical evacuation has been extensively used by military forces for evacuation of wartime casualties, but has also proven useful in civilian disaster response. Chlorogenic acid transferring ratio was investigated by temperature, pressure, time, cut-off molecular mass. Inheritance of hypoxanthine-guanine phosphoribosyltransferase deficiency and detection of heterozygotes. Dissociation of the hyperglycemic and vascular effects of glucagon. To highlight ways in which pharmacists can influence the infant mortality rate. Yet, clinical translation has not resulted in the expected benefits in human patients. Pharmacologic treatment with ivermectin, loperamide, vincristine, and other drugs that are substrates of P-glycoprotein, the MDR1 gene product, may result in neurologic toxicosis in a high percentage of Collies.

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