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Cefastar (Cefadroxil)

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Cefastar is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic. It was patented in 1967 and approved for medical use in 1978.

Other names for this medication:
Actidrox, Cedrox, Cefadil, Cefadroxil, Cefastar, Eliminate, Paxyl

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Also known as: Cefadroxil


Cefastar is a prescription medication used to treat infections of the urinary tract, skin, and throat. Cefastar belongs to a group of drugs called cephalosporin antibiotics. These work to kill bacteria. This medication comes as an oral (by mouth) tablet, capsule, and liquid (suspension). It is usually taken 1 to 2 times a day, with or without food. If Cefastar causes an upset stomach, take Cefastar with food or milk. Common side effects of Cefastar include nausea, vomiting, and diarrhea.


For urinary tract infections, the recommended daily dosage for children is 30 mg/kg/day in divided doses every 12 hours. For pharyngitis, tonsillitis, and impetigo, the recommended daily dosage for children is 30 mg/kg/day in a single dose or in equally divided doses every 12 hours. For other skin and skin structure infections, the recommended daily dosage is 30 mg/kg/day in equally divided doses every 12 hours. In the treatment of beta-hemolytic streptococcal infections, a therapeutic dosage of Cefastar should be administered for at least 10 days.

In patients with renal impairment, the dosage of cefadroxil monohydrate should be adjusted according to creatinine clearance rates to prevent drug accumulation. The following schedule is suggested. In adults, the initial dose is 1000 mg of Cefastar and the maintenance dose (based on the creatinine clearance rate [mL/min/1.73 M2]) is 500 mg at the time intervals listed below.

Patients with creatinine clearance rates over 50 mL/min may be treated as if they were patients having normal renal function.


If the patient misses a dose, the dose should be taken as soon as it is remembered. Doses thereafter should then be evenly spaced with approximately 4-6 hours between doses, depending on the prescription dosing. Patients should not make up a missed dose by doubling up on their medication. Taking double doses will not speed recovery time, either. Taking doses close together or self administering a double dose is likely to cause an overdose which may lead to other health complications. An overdose may cause nausea, vomiting, diarrhea, dehydration, and abdominal cramps and requires immediate medical assessment.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days.

Detailed Cefastar dosage information

Side effects

The most common side effects associated with Cefastar are:

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefadroxil in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefadroxil.

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