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Compazine (Prochlorperazine)

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Compazine suppositories and tablets are used to control severe nausea and vomiting. Compazine tablets are also used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions).

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

Similar Products:
Zocor, Buspar, Antabuse, Cialis, Evista, Lamictal

Also known as: Prochlorperazine


Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety. It is also used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.


Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets): For severe nausea and vomiting: Adults and children 2 years of age and older and weighs more than 39 kilograms (kg) (85 pounds (lbs))—At first, 5 or 10 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 40 mg per day. Children 2 years of age and older and weighs 18 to 39 kg (40 to 85 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 3 times a day or 5 mg 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 15 mg per day. Children 2 years of age and older and weighs 14 to 18 kg (30 to 39 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg per day. Children 2 years of age and older and weighs 9 to 13 kg (20 to 29 lbs)—Dose is based on body weight and must be determined by your doctor. At first, 2.5 mg 1 or 2 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 7.5 mg per day. Children younger than 2 years of age and weighs under 9 kg (20 lbs)—Use is not recommended. For non-psychotic anxiety: Adults—At first, 5 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 20 mg per day or longer than 12 weeks. Children—Use and dose must be determined by your doctor. For schizophrenia: Adults—5 to 10 milligrams (mg) 3 or 4 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 150 mg per day. Children 6 to 12 years of age—At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg on the first day and 25 mg per day. Children 2 to 5 years of age—At first, 2.5 mg 2 or 3 times a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 10 mg on the first day and 20 mg per day. Children younger than 2 years of age—Use and dose must be determined by your doctor.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine in children 2 years of age and older or weighing 9 kilograms (kg) (20 pounds (lbs)) and over. Use in children younger than 2 years of age or weighing under 9 kg (20 lbs) is not recommended.

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Risk of zoster in patients on immunosuppressant therapy: evaluation of current data. Effect of a calcaneo-tibial screw on medial and lateral stability of the canine tarsocrural joint ex vivo. In December 2013, an international panel of experts in the field of head and neck cancer management assembled for an Asia-Pacific head and neck cancer expert panel meeting in China. Phosphorylated mTOR and YAP serve as prognostic markers and therapeutic targets in gliomas. Ionization of histamine, N-acetylhistamine, and their iodinated derivatives. A 49-year-old man with intermittent headaches and right sided parietal lump was found to have an intraosseous right parietal lesion on computed tomography (CT) and magnetic resonance imaging (MRI). The rapid progression of gliomas has spurred the development of novel treatment options, such as cancer gene therapy and oncolytic virotherapy. Here, a novel FIFOs scheduling algorithm was proposed and the data transmission efficiency with hardware technology was improved. Each batch was derived from the domestic refuse collected from approximately 120 houses.

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Metabolic syndrome is associated with exposure to organochlorine pesticides in Anniston, AL, United States. Finally, we applied this method to isolate neurons, astrocytes, and microglia positive for PrPSc from a prion-infected mouse brain by florescence-activated cell sorting. Additionally, the action-based approach described herein allows the user to consider an arbitrarily large set of structural characteristics during the generator design process. In addition, the Indo-West Pacific genus Alcyonohippolyte was included. Effect of Nanosized NbC Precipitates on Hydrogen Diffusion in X80 Pipeline Steel. However, both Akt expression and serum treatment increased Mdm2 ubiquitination of p53.

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Anatomical study of the left superior mediastinal lymphatics for tracheal branches of left recurrent laryngeal nerve-preserving mediastinoscope-assisted surgery in esophageal cancer. Determination of Chloride in Infant Formula and Adult/Pediatric Nutritional Formula by Potentiometric Titration: Single-Laboratory Validation, First Action 2015.07. Levofloxacin containing triple treatment are recommended as rescue treatment for infection of H. We describe a 6-month-old male infant with a dermoid cyst of the left paratesticular region. The mean duration of analgesia in the bupivacaine group was 14.6 h, 10.3 in the saline group and 4.3 h in the control group.

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The comparatively better performance in terms of intuitiveness, design efficiency, and operability of the proposed master for a robotic system for minimally invasive surgery was confirmed through kinematic and experimental analysis. Present study was focused to investigate the possible mechanisms of apoptosis induced by self-designed ZnO-NSts, prepared at fix pH via solution process and exposed against human T98G gliomas including various cancers and non-malignant embryonic kidney HEK293, MRC5 fibroblast cells. Ablative Radiotherapy as a Noninvasive Alternative to Catheter Ablation for Cardiac Arrhythmias. Experimental results have been conducted in a large subsea region. The expression of c-Fos after THC treatment was analysed in several brain areas in wild-type mice and in mice lacking the PPO gene. However, it remains unclear whether these viral genomes could be reactivated. Initial input for the study consisted of experiences from 397 patients, collected using the ReproQ questionnaire.

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Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages. A 9-year cohort prospective study was conducted with nutritional evaluations of 222 children. Workplace Health Promotion in Small, Medium-Sized and Large Enterprises of the Health-Care Sector - Frequency, Reasons for the Company Management to Take Action and Barriers to Implementation. The nature of the bonding in this twin boundary is Si-C but it was rotated 180 degrees along the boundary normal. The relationships between the Hb increase and parameters used to evaluate anaemia were analysed. A female patient with diastematomyelia was followed up clinically over 14 years. Molecular self-assembly combining intermolecular crosslinking leads to resilient matrices possessing long-range ordered aqueous domains, inside which moderately aligned poorly crystalline apatite is converted from the transient amorphous calcium phosphate phase. Malignant hypertension in a child with phakomatosis pigmentovascularis type II b.

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Urinary zinc excretion during treatment with different diuretics. Secondary outcomes were drug resistance and complications of MEO. Retrospective analysis of the 2005-2010 National Hospital Ambulatory Care Survey (NHAMCS), comparing ED visits by nursing home residents that did not lead to hospital admission (potentially preventable) with those that led to admission (less likely preventable). All tumors displayed multiple CNV/CN-LOH events (median, 7.5 per tumor). To validate the analysis, we study the Brownian motion of gold nanoparticles, whose plasmonic structure allows for nanometer-scale particles to be imaged under dark-field illumination, in Newtonian liquids. Paralytic poliomyelitis is considered as flaccid paralysis in one or both legs with normal sensations and acute onset without progression. Using Western-blot analysis, amygdala phospholipase D phosphorylation and total expression of phospholipase D/5-hydroxytryptamine 2C receptor were observed in early (Day-1) and late (Day-14) withdrawal (cocaine-free) states among male Sprague-Dawley rats subjected to 7-day cocaine-conditioned hyperactivity training. Implantable neurotechnologies: a review of integrated circuit neural amplifiers.

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Content of fibrocartilagenolytic enzymes and viscosity of homogenates of joint menisci in rheumatoid arthritis. The present work seeks to examine the importance of expectancies in computer-mediated treatment and training programs. These states may be accompanied by neuropsychiatric symptomatology, suggesting continuous dynamic glucocorticoid equilibrium is essential for brain homeostasis. Rhodium-catalyzed selective CH functionalization of NNN tridentate chelating compounds via a rollover pathway. Contrary to scopolamine, anisodamine did not influence the formation of LTP in the CA(1) region of rat hippocampus at 40-fold higher dose than that of scopolamine.

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A bioautographic procedure has been developed for the visualization of the isozymes of dihydrofolate reductase (DHFR, E.C. This study retrospectively assessed whether these criteria, which differ markedly from the Dutch exclusion criteria, could predict sotalol-induced torsade de pointes arrhythmias (TdP). Exposure of the cultured cells to nanoparticles led to cell death, reactive oxygen species (ROS) increase, reduced glutathione (GSH) decrease, and the induction of oxidative stress-related genes such as heme oxygenase-1, thioredoxin reductase, glutathione-S-transferase, catalase, and a hypoxia inducible gene. A novel genetic syndrome with STARD9 mutation and abnormal spindle morphology. The effect of different treatment schemes on flow-dependent vasodilation and dynamic level of endotelin-1 (ET-1), which is a marker of endothelial dysfunction, was studied.

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Bioactive fraction of Saraca indica prevents diabetes induced cataractogenesis: An aldose reductase inhibitory activity. Detection and partial characterization of lymphoid cell surface proteases. The algorithm consisted of a fluence optimisation using the iterative least-squares technique, a segmentation and then a direct-aperture optimisation. Socioeconomic variables including no insurance, lower education, race, Hispanic ethnicity, and nonmetropolitan residence were found to be poor prognostic factors. Guanfacine (2-6 mg/day) a centrally acting antihypertensive drug, was effective in controlling blood pressure in 5 essential hypertensives and lowered plasma noradrenaline and urinary catecholamine excretion.

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The program achieved injury hazard reduction on the road, in schools, and, to a more limited extent, in the home. Qualitative evaluation of the mixed domains of co-polymers or composite films can often be accomplished with high resolution using FMM phase and amplitude images. This study aimed to investigate the dialysis efficacy of low-flux versus high-flux membranes in hemodialysis patients. However, little is known about the risk for violence exposure among the children of women seeking elective pregnancy termination. Primary amoebic meningo-encephalitis: clinical, pathological and epidemiological features of six fatal cases. In addition, important physiological variables zyrtec generic name seem to show acute recovery patterns consistent with recovery of function in chronic animals. It is important to assess the cerebral hemodynamic status in patients with this chronic condition.

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To determine the effect of regional supply and demand disparities on patient outcomes, we performed linear regression and multivariate Cox regression analyses. Three-dimensional computed tomographic reformations of intracranial vascular lesions. A Dimensionality Reduction-Based Multi-Step Clustering Method for Robust Vessel Trajectory Analysis. Dysthyroid optic neuropathy (DON) is a severe manifestation of thyroid eye disease (TED) that can result in permanent vision loss. The syndrome was tolterodine detrol 2 mg tablet found in 49 patients with gastrojejunostomy (30 percent of those at risk) but in only 2 patients with esophagojejunostomy (8 percent, p less than 0.05). However, further research is needed to look at variables affecting disc space pliability, implant subsidence, in vivo application, and clinical benefit of this procedure.

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RNs provided explicit stories of identifying medication order discrepancies as well as examples of clinical reasoning to assure medication order appropriateness whereas LPNs described comparing medication lists. These include antiparasitic effects, anti-depressive effects, anti-fatigue effects, antioxidant effects, antibacterial and antifungal effects, antihypertensive effects, anti-inflammatory and analgesic effects, anti-allergic effects, the promotion of digestive functions, suppression of platelet aggregation, regulatory effects on blood glucose and lipids, etc. Using Dust Assessment Technology to Leverage Mine Site Manager-Worker Communication and Health Behavior: A Longitudinal Case Study. Minimum inhibitory concentration distributions for first- and second-line antimicrobials against Mycobacterium tuberculosis. Review was made of the charts of 131 patients with community-acquired pneumonia admitted to the hospital and treated with broad-spectrum parenteral antibiotics in whom a specific pathogen was never isolated. Spontaneous mutations in KNOX genes give rise to a novel floral structure in Antirrhinum. Electrophysiological and ultrastructural studies of intercellular junctions in brown fat. Inhibition of estrogen-induced renal carcinogenesis in male Syrian hamsters by tamoxifen without decrease in DNA adduct levels. An biaxin medication in vitro ethnopharmacological study on Prangos ferulacea: a wound healing agent.

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This Working Group has been composed of internationally recognized scientific experts from tenormin 25 mg dosage tick-borne encephalitis virus (TBEv)-endemic and non-endemic regions with extensive personal expertise in the field and a high level of commitment to improve the knowledge of TBE and to increase the public awareness of TBE. Results of this study indicate that brivudine may be the first choice in severe HZ cases as it controls pain earlier and is easier to use because of its once daily administration. Extracellular space, electrolyte distribution, and resting potential in K depletion. This was mainly explained by increasing aeroallergen sensitization among 4-11 year olds. Diversity and accessibility of smoking cessation aids in the internet. Longitudinal research is needed to support temporal associations and explore behavioral mechanisms linking leptin to illness trajectory. Results of this study found the M6-C device to produce positive clinical and radiographic outcomes similar to other cTDRs, warranting further investigation. Implications of probability analysis on the strategy used for noninvasive detection of coronary artery disease. Unlike sis/PDGF-2, which remains tightly cell-associated, another growth factor, termed transforming growth factor alpha (TGF alpha), is actively secreted.

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Magnetic resonance imaging (MRI) and angiography (MRA) revealed no vascular abnormality. mutans endocarditis is capable of causing significant morbidity and mortality, as exemplified by the prolonged and complicated hospital course of our patients and the ultimate death of one of them. This study indicates that the second stage of sleep seems to be associated with an increase in negative BOLD response to internal activity compared with sleep stage 1. The current procedures are exposed and the available literature on implant removal in children reviewed. i) Assess the geriatric profile according to ISAR score ii) correlate the score to outcomes two months after Emergency Department (ED) visit. The low CV values in high and low SNR datasets show that PDE-levels can be accurately and reproducibly quantified in all conditions. The molecular orientation and its field-free decay were monitored with a time resolution of 2 milliseconds by means of synchrotron radiation and a multiwire proportional area detector. This study analysed the major South African mining recruitment database for the period 1973 to 2012 by calendar intervals and demographic and occupational characteristics. Our findings showed that LA function gradually deteriorated from patients with normotension, across patients with daytime hypertension, to patients with night- and day-nighttime hypertension.

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Using pattern recognition to analyze aged-grouped pharynx images, we identified discrete step-wise transitions between distinct morphologies. The EDTA-treated expanded satellite tobacco necrosis virus: biochemical properties and crystallization. However, this alteration is not necessarily expressed by established mammary tumor cell lines. Effects of washing with saline solution and normal bovine plasma on the infectivity of Anaplasma marginale erythrocytes. Determinants that increase the serum resistance of Escherichia coli. Recently published results, from this group, on rat cervical spinal cord, a late responding tissue, indicated no further alfuzosin 10 mg sparing with lowering the fraction size from 2 to 1.8, 1.5, and 1.3 Gy. The relationship between body weight and blood pressure, total serum cholesterol, triglycerides, uric acid and glucose was investigated in 203 psoriatic patients in comparison with 904 healthy controls.

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Acute pyelonephritis including an overlooked renal cell carcinoma. The retrospective study was conducted at Shifa International Hospital and comprised records of all patients with lesions of female genital tract who underwent frozen section between January 2010 and December 2012. Since municipalities implemented the reform at different can you drink alcohol while taking bactrim times, we have both cross-sectional and time-series variation in the reform instrument. Disseminated carcinomatosis of the bone marrow is reported to have a poor prognosis, but paclitaxel plus bevacizumab is a possible effective chemotherapy. We used homology modeling and molecular dynamic simulations of the hP2X3R to identify inter-subunit interactions of residues that are instrumental to elucidate conformational changes associated with gating of the hPX3R.

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European policy-makers and public may perceive asthma as more burdensome than it is and COPD much less. At baseline and at 1.5, 6, and 12 months post-baseline, 24-h room calorimetry, body composition, and fasting blood biochemistries were measured in 11 obese adolescents relative to five matched controls. Our results help us to understand the biological consequences of ion fragmentation through materials, whether in space or in the clinic, and provide us with a biological basis for the use of hydrogenous materials like PE as effective space shields. During meiotic maturation, the cortex of oocytes of Xenopus laevis undergoes structural reorganization, visualized in this study by freeze-fracture electron microscopy. The shape of the implant and the operative technique also play an important role in achieving a successful oral implant. More social supervisor support as perceived by staff was found to predict less activity involvement. PDSA forced to cut services as economic depression takes its toll. The selectivity of peptides as an enzymatic substrate has thus been utilized to construct enzyme sensors or enzyme-activity sensors. An electrokymographic study of pulmonary ventilation and circulation in cancer of the lung. This scoping review included nine studies published over an eight-year period that investigated or described the effects of medication safety programs in primary care settings.

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Using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), we retrospectively evaluated 84 OCD patients who responded to a 10- to 12-week, open-label, acute treatment in a naturalistic clinic setting. Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as an urgent public health threat. Identification and management of women at high risk for pelvic infection following cesarean section. There is no consensus on what level of IPV constitutes a risk of graft loss. Flow-cytometric measurements of the transmembrane potential, the surface charge density and the phagocytic activity of Guinea pig macrophages after incubation with lymphokines. Most of DFIs specimens were poly microbial infection and predominant bacteria were S. The routine examination of prostatic fluid showed increased leukocytes and the culture of prostatic fluid showed Morganella morganii subsp. We found that the peptide 5HR exhibited low-to-moderate inhibitory activity on HIV-1-mediated cell-cell fusion, whereas addition of LBD and/or PBD to the HR sequence resulted in a significant increase of the anti-HIV-1 activity. The development of guidelines specific to the treatment of early AC could standardise treatment while further research is required to define the optimal management of T1N0 AC and AIN.

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