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Detrol

Detrol is a urinary antispasmodic, meaning it helps with bladder spasms or the urge to urinate. It blocks certain receptors in the bladder so that your bladder muscles can relax. This helps you have better control over your urination.

Other names for this medication:
Bapter, Concys, Detrusitol, Dezrolala, Flochek, Roliten, Terol, Tolter, Tolterodine, Uftol, Uridin, Urotel

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Also known as: Tolterodine

Description

{name} LA is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage).

Dosage

Detrol can be taken in form of tablets, liquid pills, chewable pills, drops which should be taken by mouth. Take Detrol tablets orally with or without food. Do not crush or chew it. Take Detrol at the same time with water. If you want to achieve most effective results do not stop taking Detrol suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Detrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Detrol if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have:

trouble emptying your bladder; a blockage in your stomach, slow digestion; or uncontrolled narrow-angle glaucoma.

To make sure Detrol is safe for you, tell your doctor if you have::

a stomach or intestinal disorder; problems with constipation; liver disease; kidney disease; myasthenia gravis; trouble emptying your bladder, or a weak stream of urine; glaucoma; or long QT syndrome (in you or a family member).

Tell your doctor if you are pregnant or breastfeeding.

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Thus, determining the phosphorylation status of the M1 mAChR at Ser(228) not only provides a means of establishing receptor activation following drug treatment both in vitro and in vivo but also allows for the mapping of the activation status of the M1 mAChR in the hippocampus following memory acquisition thereby establishing a link between M1 mAChR activation and hippocampus-based memory and learning. Interactions of sulindac and its metabolites with phospholipid membranes: an explanation for the peroxidation protective effect of the bioactive metabolite. JTT-130 also enhanced glucose-stimulated insulin secretion in hyperglycemic clamp tests, whereas increased insulin sensitivity was observed in hyperinsulinemic-euglycemic clamp tests. Argininosecologanin, a secoiridoid-derived guanidine alkaloid from the roots of Lonicera insularis. In contrast to the electrophilic radicals H and OH they are nucleophilic and the hydroxymethyl radicals add exclusively at the C(6) position of 1,3-dimethyluracil (k approximately 10(4) dm3 mol-1 s-1).

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More basic research is also required to improve what we can still consider as first-generation vaccines, and to explore possible new paradigms including the search for cross-protective antigens. Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014. Antibacterial drugs, the lipid A inhibitor polymyxin B and the TRPV1/TRPA1 channel pore-passing anesthetic QX-314, suppressed both the spontaneous pain and the mechanical allodynia. A significant acceleration of the healing by local injections with GM-CSF was demonstrated. In vivo incorporation of leucine-3-H into thyroglobulin of microsomal subfractions of the rat thyroid. Then we evaluated the impacts of MetS and its five components on HRV. tcPco2 measurements in the fetus during labor were evaluated by analysing the clinical experience in 224 cases. To study the occurrence of sagittal malalignment, the adaptability of a simplified sagittal modifiers grading of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity classification (ASD), and the deformity-specific SRS questionnaire version 30 (SRS-30) in an unselected adult cohort with symptomatic degenerative spinal disorders. Our results demonstrate that the net magnetic properties of a molecular submonolayer can be tuned using a graphene spacer layer, which is attractive for hybrid molecule-inorganic spintronic devices.

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To explore the effect of bone morphogenetic protein-2 (BMP-2 ) on the expression of membrane Type 1-matrix metalloproteinase (MT1-MMP) and the activation of matrix metalloproteinase-2 (MMP-2) in human A549 lung carcinoma cells. Concurrent radiation and imatinib may represent a viable treatment option for unresectable and symptomatic desmoid tumors where rapid relief is needed to prevent permanent loss of function. Postprandial dyslipidemia in insulin resistance: mechanisms and role of intestinal insulin sensitivity. Light of one colour was paired with pain stimuli of moderate intensity (control stimuli), and light of the other colour was paired with either nonpainful stimuli (in the placebo group) or painful stimuli of high intensity (in the nocebo group). Functions of unconventional myosins in the yeast Saccharomyces cerevisiae. Family pedigrees of six children with severe school phobia compared with those of a matched group of families of five children with psychiatric disorders showed a clustering of affective and anxiety disorders. Spatio-Temporal Variation of Longevity Clusters and the Influence of Social Development Level on Lifespan in a Chinese Longevous Area (1982-2010).

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Unveiling the stimulatory effects of tartrazine on human and bovine serum albumin fibrillogenesis: Spectroscopic and microscopic study. in pig farms and slaughterhouses in two provinces in northern Thailand. The initial PGE2 dose was 0.5 mg, followed by 1.0 mg every hour for up to 24 hours. Acute subdural hematomas (ASDHs) are rarely reported in the literature. When should stable maturity-onset diabetics be switched to insulin?. Continuous exposure of non-small cell lung cancer cells with wild-type EGFR to an inhibitor of EGFR tyrosine kinase induces chemoresistance by activating STAT3. The purpose of this study was to explore how a formative objective structured clinical examination (OSCE) drives learning. Fixation with EDCDI also allowed detection of histamine in gastric enterochromaffin-like cells and mast cells in rat. Action of thyroid hormones on oxido-reduction state of respiratory coenzymes.

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Ischemia-reperfusion syndrome is a condition where the role of oxygen free radicals is important. Large DTR had the higher risk estimates of HFMD incidence in cases of EV71 infection, while small DTR had the higher risk estimates of HFMD incidence in cases of CV-A16 infection. Neuropsychological phenotype and psychopathology in seven adult patients with Phelan-McDermid syndrome: implications for treatment strategy. Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection. Vitamin D supplementation in vitamin D-deficient, elderly people improved muscle strength, walking distance, and functional ability and resulted in a reduction in falls and non-vertebral fractures. Also when women whose blood pressure rose to 140/90 mmHg or above after NaCl loading were classified as those positive in NaCl loading test, all the normal pregnant women were negative, but among the patients with hypertensive pregnancy, a positive reaction was represented in half of them in spite of the treatment. Glycogen phosphorylase is the key enzyme that breaks down glycogen to yield glucose-1-phosphate in order to restore depleted energy stores during cerebral ischaemia. Nonradiographic axial spondyloarthritis is a new classification concept.

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In this population treated with predominantly new-generation drug-eluting stents, diabetic patients were at increased risk for repeat target-lesion revascularization consistently across the spectrum of disease complexity. We report details of a 6 1/2-year-old girl who developed porphyria cutanea tarda after allogeneic bone marrow transplantation for chronic myelogenous leukaemia. Seventy-seven patients with multiple common warts were screened for a double-blind study using levamisole. Replication of double-stranded RNA of the virus-like particles in Saccharomyces cerevisiae. The outcome of the mating competition experiments depended on the methodology used to mark the males. Under the electron microscope the grafted granule cells had normal-appearing dendrites bearing the normal types of spines and forming the normal types of synapses. HepG2 liver cancer cells cultured in the presence of gold nanoparticles achieved adequate heating to cause cell death upon exposure to the RF field with no cytotoxicity attributable to the gold nanoparticles themselves. Because so little is known of its natural history and potential for malignancy we recommend radical nephrectomy as the treatment of choice.

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A novel excitatory higher-order input (named Input-HO) to the feeding network of the pond snail, Lymnaea stagnalis, as well as a reliable procedure that makes it possible to initiate and maintain the Input-HO, are described. A combination of CytoGam plus ganciclovir in OLT recipients has resulted in reductions in CMV hepatitis and infection, and CMV disease and viremia, plus a trend in improved 1- and 2-year survival rates. Predictions about tissue viability and clinical recovery following cerebral ischemic events can be more accurately made once quantitative information is available regarding cerebral blood flow and concomitant cerebral metabolism. The primary surgical treatment of injured soft tissues of the maxillofacial area is performed with special reference to anatomo-physiological features of the injured area, mechanism and character of the trauma. By combining experiments and computational modeling, the fundamental rules that can predict the folding behavior of sheets with a variety of stitch-patterns are elucidated.

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During pedobarography, we collected the subarch angle and arch index as well as the center of pressure xanax pics of pills progression (COPP) on all subjects. The purpose of the study is to evaluate and quantitate intra-operative stress in surgical trainees. Antileukemic effect of chronic graft-versus-host disease: contribution to improved survival after allogeneic marrow transplantation. The biological activities of kumatakenin, a flavonoid that has recently been isolated from cloves, are poorly characterized. This study was therefore done to determine the level of demand and unmet need for family planning among women on ART in South Gondar and North Wollo Zones, Amhara region. MiRNA-125b inhibits proliferation and migration by targeting SphK1 in bladder cancer. To explore and understand barriers nurses perceive in undertaking bedside handover.

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This is in accordance with other data pointing to the transmitter function of glutamate and/or aspartate in the perforant path and pyramidal cell axons. Seroprevalence of anti-Chlamydia trachomatis IgM in neonatal respiratory tract infections in Hungary. Results of test kits for the identification of periodontopathogens are significantly influenced by the detection technology applied. Data were collected from clinical examinations as well as patient questionnaires. In addition to surfactant-templating of hierarchical silica structures, polypeptides from marine organisms may offer biological routes to novel silica materials. A novel method of labeling and characterizing migrating neurons in the developing central nervous system. Taken altogether, this study established a model for global response mechanisms to HL in Synechococcus 7002 and may be valuable for further studies addressing HL resistance in photosynthetic organisms. Because these injuries are markedly unstable and cannot be suitably realigned and reduced by external means, early surgical therapy should be considered. In conclusion, our study demonstrated that asymmetric force exerted different effects on the cartilage, subchondral bone and collagens of TMJs.

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Beta-substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine beta-hydroxylase. Kocuria flava HO-9041 isolated from the air of Xinjiang of China, is a Gram-positive, aerobic, coccoid, nonencapsulated, non-halophilic, and non-endospore-forming, in the genus Kocuria, and it shows the ability to remove heavy metal. One patient with a primary gastrointestinal (GI) malignancy with minimal volume disease experienced a surgically defined complete remission. Effects of nitrogen addition on soil microbes and their implications for soil C emission in the Gurbantunggut Desert, center of the Eurasian Continent. Use of the new stirrups in the second group significantly decreased the postoperative morbidity associated with the dorsal lithotomy position from 13.3 to 2.6 per cent (p less than 0.05). Ionization currents imipramine hcl tablet 25 mg in liquid ionization chambers: low conductivity liquids.

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Gene-fusion studies of transcriptional and post-transcriptional regulation in a ribosomal/RNA polymerase operon of Escherichia coli. To explore the mechanism of action of butylphalide (NBP) against the injury following oxygen glucose deprivation/reoxygenation (OGD/R) in rat cortical neurons, neurons of Wistar newborn rats were prepared by filtering through a mesh, centrifugation and trypsogen digestion. Distinguishing true infection from synovial fluid culture contamination in patients with suspected septic arthritis. A response surface plot is also presented to graphically represent the effect of the independent variables on the percent of friability and the disintegration time. Gainful employment reduces stigma toward people recovering from schizophrenia. Phylogenetic analysis using pierisin proteins from Pierid butterflies, ADP-ribosylating toxins from bacteria, human, rat, and mouse indicated the possibility of horizontal transfer of pierisin genes from bacteria to butterflies.

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Insights emerging from this work have consequences for our understanding of changes in biosphere function since the Late Pleistocene and of the functioning of contemporary ecosystems, as well as offering a rationale and framework for scientifically informed restoration of megafaunal function where possible and appropriate. Human antimicrobial peptide LL-37 induces glial-mediated neuroinflammation. New method of treatment of aniseikenia by means of localization exercises. A total of 123 isolates of Cladosporium spp., Exophiala spp., Fonsecaea spp., Lecythophora hoffmannii, Phaeoannellomyces werneckii, Phialophora spp., Wangiella dermatitidis, and Xylohypha bantiana were tested for proteolytic activity by using 26 different formulations of gelatin, milk, casein, and Loeffler media. Gait characteristics of children and youth with chemotherapy induced peripheral neuropathy following treatment for acute lymphoblastic leukemia. WBi results, which can cause delays in determining HIV status, were relatively common with the 3rd generation assay. Efficacy and safety of sugammadex (Org 25969) in reversing deep neuromuscular block induced by rocuronium or vecuronium in Japanese patients. Studies on bridging therapy are heterogenous and due to ethical issues, mostly of retrospective design. The cardiovascular response might be dependent on the type and severity of stressors, the complexity of stress reaction and the ability of man to counteract stress. The recent introduction of mass cytometry, a technique coupling a cell introduction system generating a stream of single cells with mass spectrometry, has greatly increased the number of parameters that can be measured per single cell.

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Most of the modern hospitals are constructed in the pattern of Rigs. Nerve cell dissociated from the cerebral cortex of mice were co-cultured with isolated pancreatic islets of Langerhans. The significance of persistent atrial late potentials in right atrium during biatrial pacing. To compare the effectiveness and safety of two strategies for treating BP. Co-precipitates of starch with different silicates were prepared and FTIR-ATR, XRD and SEM techniques were used for the characterization of conjugates. Content and thematic analyses were used to analyze patterns related to the influence of BPCs on breastfeeding. These complications were managed during the course of treatment and they did not affect the final outcome in all patients except three. Novel non-epithelial effects of aldosterone are mediated via a second messenger biaxin antibiotic uses system, which involves activation of the sodium/hydrogen antiporter.

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Maintenance therapy will succeed to repeated achievement of remission of angiomas. Given the predisposition of dogs to coccidioidomycosis, identification of high-risk regions for coccidioidomycosis in dogs may improve early recognition of emerging human disease. Since thiamine pyrophosphate is an essential product involved in a variety of metabolic pathways, proteins responsible for its production satisfied these two criteria. We demonstrate that BBS mutant mice have defects in retinal outer segment morphogenesis. Patients with a diagnosis of malignancies requiring inguinal lymphadenectomy at Emory University were enrolled in the study, and informed consent was obtained. This shows that the progression signal of SK-BR3 cells is retarded completely by the precise binding of antibody to the human epidermal growth factor receptor 2 receptor of the breast cancer cell membrane, causing cell death. The SOCS1/FLT3-ITD double transgenic fish could further facilitate the leukemic process.

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Trials in castration-resistant prostate cancer (CRPC) treatment have shown improved outcomes, including survival. Mycological Profile and Antifungal Susceptibility of Fungal Isolates from Clinically Suspected Cases of Fungal Rhinosinusitis in a Tertiary Care Hospital in North India. Models were trained using in house high-throughput assay data reported as the predicted human hepatic clearance by liver microsomes or pCLh. Predictive value of serum insulin-like growth factor-1 in hepatocellular carcinoma. Case of spontaneous splenic rupture caused by ectopic pregnancy in the spleen. The pharmaceutic serum of Rougan Jiedu formula was prepared and the influence of the pharmaceutic serum of Rougan Jiedu formula to the cell proliferation of hepatoma carcinoma cell HepG2, SMMC-7721 was observed. Its high specificity concerning rodents is established at the highest rate in Ratus Norvegicus and inbred mice - C57 Black. The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain.

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A brief overview of the 1999 CDC Guideline for the Prevention of Surgical Site Infection. Their acceptor arms are aminoacylated with specific amino acid residues while their anticodons delimit codon specificity. Dissolved concentrations of both Hg and As decrease with increasing chlorophyll concentrations suggesting that there is significant uptake of metal from water by algae. Experimental CHS in mice has been used by many laboratories as a model of T-cell-mediated immune responses to antigens deposited onto the skin to study the priming, development, and function of effector and regulatory T-cell components levaquin sinusitis dosage during these responses. The overproduction of value-added terpenoids and the efficient mining of new terpenoids represent major challenges in the fields of metabolic engineering and natural product discovery. In a real-world application, we used the algorithm for cancer subtyping, identifying subtypes of cancer from heterogeneous datasets.

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The primary aim of the current study was to evaluate whether MAT-sf scores can be used to identify risk for major mobility disability (MMD). A standardized algorithm for initial diagnostic and treatment has proven to be helpful. Women with chronic vulvar pain were asked to complete a questionnaire whilst waiting for specialist consultation by either a dermatologist, sexual health physican, psychologist or physiotherapist. A part from their antihypertensive effect, they also improve cardiac, cerebral and intra-renal haemodynamics. Multiplex analysis of plasma cytokines/chemokines showing different immune responses in active TB patients, latent TB infection and healthy participants. This phenotype exists in a proportion of the F2-generation from an intercross between C57L/J and SWR/J mouse strains.

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