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Fasigyn (Tinidazole)
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Fasigyn

Fasigyn is used to treat infections caused by protozoa (eg, trichomoniasis, giardiasis, and amebiasis). It is also used to treat adult women with vaginal infections (bacterial vaginosis). Fasigyn belongs to the group of medicines called antiprotozoals.

Other names for this medication:
Simplotan, Tindamax, Tinidazole

Similar Products:
Sporanox, Lodine, Propecia, Wellbutrin, Soma, Loxitane, Dostinex, Hytrin, Asacol

Also known as: Tinidazole

Description

Fasigyn 500mg film-coated tablets contain 500mg of the active substance tinidazole. This medicine is an anti-infective agent. It is used to treat a variety of bacterial infections including: infections of the skin, blood, chest, lung, genitals or womb lining, an infection associated with stomach ulcers in combination with other drugs, infections caused by organisms called protozoa, such as amoebiasis and giardiasis (stomach infections) and trichomoniasis (a genital infection), vaginal infections (vaginitis) and gum infections (gingivitis).

It is also used before certain surgical operations to prevent bacterial infections developing.

You should ask your doctor if you are unsure why you have been given this medicine.

Dosage

Fasigyn tablets should be taken with plenty of water with or after meal. Swallow Fasigyn tablets whole, do not chew or crush. Fasigyn is not recommended for use in children less than 12 years. For urogenital Trichomoniasis: The recommended dose is 4 tablets (2 g) given as a single dose. For amoebic involvement of the liver (a liver infection): the recommended dose is 3 to 4 tablets (1,5 to 2 g) once a day for 3 to 6 days. For the infection associated with stomach ulcers: the recommended dose is 1 tablet (500 mg) taken twice a day. For most bacterial infections: the recommended dose is 4 tablets (2 g) on the first day then 2 tablets (1 g) once a day or 1 tablet (500 mg) twice a day. The usual length of treatment is 5 to 6 days. For bacterial vaginitis (a vaginal infection) and acute ulcerative gingivitis (a gum infection): the recommended dose is 4 tablets (2 g) given as a single dose. For vaginitis you may be given 4 tablets (2 g) on two consecutive days. For protozoal infections (intestinal amoebiasis): the recommended dose is 4 tablets (2 g) once a day for 2 to 3 days. Prevention of postoperative infections in adults (over 12 years): the recommended oral dose of 2 g approximately 12 hours before surgery.

Overdose

In acute animal studies with mice and rats, the LD50 for mice was >3600mg/kg and >2300mg/kg for oral and intraperitoneal administration respectively. For rats, the LD50 was >2000mg/kg for both oral and intraperitoneal administration.

Signs and symptoms of overdosage: There are no reported overdoses in humans with Fasigyn.

Treatment for overdosage: There is no specific antidote for treatment of overdosage with tinidazole. Treatment is symptomatic and supportive. Gastric lavage may be useful. Tinidazole is easily dialysable.

Storage

Keep Fasigyn in its original packaging until it is time to use it. If you take Fasigyn out of its packaging, it may not keep as well.

Keep your Fasigyn in a cool, dry place where it stays below 25 degrees C.

Do not store Fasigyn or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill. Heat and dampness can destroy some medicines.

Keep your Fasigyn where young children cannot reach it. A locked cupboard at least one and a half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Fasigyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Fasigyn if you are allergic to Tinidazole, to any antibiotic from the class Amebicides. Do not take Fasigyn if you are allergic to any of the other ingredients comprised in Fasigyn. Do not take Fasigyn if you have a history of severe allergic reactions associated with using antibiotics. Do not take Fasigyn you have a blood disorder or a history of blood disorders. Do not take Fasigyn if you have any disease of the brain, spinal cord or nerves. Do not take Fasigyn you have central nervous system (CNS) disease, including epilepsy. Do not take Fasigyn you are in the first 13 weeks of pregnancy, planning to have a baby, or you are breastfeeding. Do not drive or operate machinery if you feel dizzy or numb after taking Fasigyn. Do not consume alcohol while you are taking Fasigyn and for 3 days afterwards. Alcohol may cause an upset stomach, vomiting, stomach cramps, headaches, sweating, and flushing (redness of the face).

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