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Letzit (Montelukast)

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Letzit is used to control and prevent symptoms caused by asthma (such as wheezing and shortness of breath). This medication can help decrease the number of times you need to use your quick relief inhaler.

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Also known as: Montelukast


Letzit tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.


Take Letzit chewable tablets (4 mg, 5 mg, 10 mg), granules, film-coated tablets orally with water. Usually Letzit is taken as a single dose at least two hours before you exercise. Do not take another dose of Letzit for at least 24 hours. Usually Letzit is taken once a day in the evening with or without food. Do not take Letzit for asthma attack treatment that has already begun. If you want to achieve most effective results do not stop taking Letzit suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Letzit are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Letzit if you are allergic to its components or to aspirin. Do not take Letzit if you use Letzit while you are pregnant or have nurseling. You should not use Letzit for exercise-induced bronchoconstriction if you already take Letzit to prevent symptoms of allergy or asthma. Try to be careful using Letzit if you take phenobarbital (such as Solfoton, Luminal), rifampin (such as Rifamate, Rifadin, Rimactane, Rifater). It can be dangerous to use Letzit if you suffer from or have a history of phenylketonuria, liver disease. Avoid any activities such as driving or operating machinery while taking Letzit. It can be dangerous to stop Letzit taking suddenly.

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