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Metformin

Metformin is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Other names for this medication:
Asoride, Avimet, Bemet, Cetapin, Daomet, Diapride, Dibimet, Duomet, Exmet, Formin, Glibetic, Glimaday, Glimid, Gluconorm, Glumet, Glycinova, Glyciphage, Glycurub, Glyformin, Glysiss, Insumet, Medformin, Mefinda, Mefomin, Metafor, Metalok, Metanorm, Metsar, Metsig, Minimet, Okamet, Ovinom, Reglide, Riomet, Risicon, Rosimet, Sumet, Vogic, Vogipax, Volabay, Wymet, Zoform, Zolmelis

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Description

MetFORMIN (Eqv-{name} XR) is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

MetFORMIN (Eqv-{name} XR) is sometimes used together with insulin or other medications, but MetFORMIN (Eqv-{name} XR) is not for treating type 1 diabetes.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take MetFORMIN (Eqv-Metformin XR) with a meal, unless your doctor tells you otherwise. Some forms of MetFORMIN (Eqv-Metformin XR) are taken only once daily with the evening meal. Follow your doctor's instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

MetFORMIN (Eqv-Metformin XR) is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Your doctor may have you take extra vitamin B12 while you are taking MetFORMIN (Eqv-Metformin XR). Take only the amount of vitamin B12 that your doctor has prescribed.

Detailed Metformin dosage information

Overdose

Do not take Metformin tablets in large quantities. In case of Metformin overdosage, you need to visit doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metformin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use MetFORMIN (Eqv-Metformin XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Metformin XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Metformin XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Metformin XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Metformin XR) are not approved for use by anyone younger than 18 years old.

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It is well known that pain perception for patients and normal subjects can be modulated by psychological factors, such as attention, stress, and arousal. Interaction of spherical particles with cells and within animals has been studied extensively, but the effects of shape have received little attention. A database derived largely from information down-loaded from existing hospital-based systems includes the results of individual CSF laboratory studies, in addition to the patient age, primary diagnoses, and details of any malignancy. Protective coatings for intraocular wirelessly controlled microrobots for implantation: Corrosion, cell culture, and in vivo animal tests. The Neer I (polyethylene glenoid), Neer II (plastic glenoid surface with metal backing), Cofield, and Gristina monospherical total shoulder prostheses were tested for joint subluxation resistance and glenoid component fixation strength. Abnormally High Ankle-Brachial Index is Associated with All-cause and Cardiovascular Mortality: The REGICOR Study. Should preventive antibiotics be used in patients with acute stroke?. The antibacterial effects for Salmonella Enteritidis phage type 4 of different chemical disinfectants and cleaning agents tested under different conditions.

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Reentrant ventricular rhythms in the late myocardial infarction period: prevention of reentry by dual stimulation during basic rhythm. The ability to change work hours and the ability to take work home were associated with increased home spillover to work. In addition, HCT does not seem to cross the blood brain barrier in rats. Assessment of the prognostic value of clinico-morphologic factors in breast cancer using a computer. Enzymatic inhibitory activity and trypanocidal effects of extracts and compounds from Siphoneugena densiflora O. A 23-year-old man presented with a 3-week history of left hearing disturbance and left facial nerve paresis. The data suggest that the fluorogenic method is more reliable and shorter to how many mg of motrin perform than the standard ISO method. A novel microflow cell with a nitrobenzene (NB)/water (W) interface was developed. Many studies showed that sST2 brings important prognostic information in patients with heart failure. 50th anniversary of the Central Order of Lenin Institute of Higher Medical Education.

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However, few studies have involved in the health training status and needs assessment of rural Chinese nurses in great transformations of health policy. Identification of cardiac rejection with magnetic resonance imaging in heterotopic heart transplantation model. GISP also inhibits TSG101-dependent GABA(B2) down-regulation in human embryonic kidney 293 cells whereas over-expression of a mutant GISP lacking the TSG101 binding domain has no effect on GABA(B2) degradation. Parent alcohol problems were indirectly linked to adolescent drinking through familial abuse and its relationship to deviant peers, time on own and risky subsistence behaviors. Asexual spores (conidia) of Aspergillus nidulans contain a dark green pigment which is not present in other cell types. Nicotinic acetylcholine receptor: a structural model for alpha-subunit peptide 188-201, the putative binding site for cholinergic agents. Histologic examination of uteri from cPten(f/f)Grp78(f/f) mice also revealed no complex atypical hyperplasia, a well-established EAC precursor. After institutional review board approval, the records of 563 consecutive patients admitted with spontaneous SAH between January 2007 and 2014 were retrospectively reviewed. Significantly higher 5-HT levels and lower 5-HT turnovers 5-hydroxyindole acetic acid ((5-HIAA)/5-HT) were found in the brains of HFD-EAE mice compared with those found in the HFD-CON and ND-EAE mice brains.

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Commercial Truck Driver Health and Safety: Exploring Distracted Driving Performance and Self-Reported Driving Skill. The Uniformity of Dosage Units test published in the United States Pharmacopeia 24 (USP), which applies to whole tablets, was adapted liberally to assess the dose uniformity of the resulting split tablets. This article reviews evidence that links AFLP with both genetic and acquired factors that compromise intramitochondrial fatty acid oxidation. The aim of the present study was to determine the reliability and validity of the Persian translation of the SHQ (Spatial Hearing Questionnaire). Our results suggest that shRNA directed against hTERT inhibits cell viability by regulating telomerase activity and its related protein expression in NPC cells. The HPLC fingerprints, developed on two coupled Chromolith RP-18e columns, using a gradient mobile phase (methanol/water/trifluoroacetic acid, 5:95:0.05, v/v/v), showed more peaks than the TLC profile. Autosomal recessive non-syndromic hearing loss (ARNSHL) is highly heterogeneous, and mutations in the gene encoding transmembrane channel-like 1 (TMC1) have been implicated in its development. Effect of a Discharge Planning Educational Program in a University Hospital. Multiple variables affect the tissue destruction caused by missiles, and the interaction of these variables is incompletely understood.

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The data suggest that PACAP has a neuroprotective effect on the hippocampal neuronal damage induced by glutamate, which is related to an inhibition of glutamate-induced increase of intracellular calcium concentration and mediated by PACAP type I receptor. Subsequent boosting of these rabbits with a clade B HIV-1 Bal gp145 resulted in an expanded breadth of neutralization of HIV-1 isolates. These poor results were associated with older age, poor anatomical reduction and, in some, the presence of a midcarpal instability pattern. The Canadian Association of General Surgeons commissioned a task force to review the evidence regarding the management of blood-borne pathogens and transmission risk during surgical procedures. Our model encompasses sampling error of the survey estimates, area specific random effects, autocorrelated area by time random effects and hence, borrows strength across areas and time points both. Several key elements emerge as critical to the ultimate success of a clinical trial, including the probability of receiving placebo, study duration, dosing schedule, visit frequency, the use of blinded lead-in phases, the use of centralized raters, illness severity and duration, and comorbid anxiety. Skin tumors in ACI-N rats induced by 3-methylcholanthrene and 4-dimethylaminostilbene. Twelve cats were assigned equally to two groups, one with normal, and the other with artificially-increased intracranial pressure. The binding signal of one known fluorinated ligand was measured by determining the displacement of the known ligand. The Auditory Nerve Overlapped Waveform (ANOW) Detects Small Endolymphatic Manipulations That May Go Undetected by Conventional Measurements.

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