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Onotrex (Methotrexate)

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Onotrex is a chemotherapy agent and immune-system suppressant. It is used to treat cancer, autoimmune diseases, and ectopic pregnancy and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, gestational trophoblastic disease, and osteosarcoma.

Other names for this medication:
Beltrax, Biotrexate, Caditrex, Carditrex, Cytotrex, Dermotrex, Folitrax, Imutrex, Merex, Methocip, Methorex, Methotrexate, Metorex, Metrex, Neotrexate, Nidtrex, Oncotrex, Onotrex, Plastomet, Remtrex, Rextop, Roxate, Tevatrex, Throtex, Trixilem, Vibzi, Zexate

Similar Products:
Protonix, Aldactone, Glucophage, Levitra, Levlen

Also known as: Methotrexate


Generic Onotrex is used for treating disorders associated with high prolactin levels: persistent breast milk production, lack of a menstrual period, infertility, and other conditions. Generic Onotrex is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland. Onotrex is also known as Cabergoline, Cabaser, Colette, Caberlin. Generic name of Generic Onotrex is Cabergoline. Brand name of Generic Onotrex is Onotrex.


This section provides information on the proper use of a number of products that contain permethrin. It may not be specific to Onotrex. Please read with care.

Keep this medicine away from the eyes. If you accidentally get some in your eyes, flush them thoroughly with water at once.

Permethrin lotion which is used to treat lice, comes in a container that holds only one treatment. Use as much of the medicine as you need and discard any remaining lotion properly.

For the treatment of head lice (1% lotion):

Shampoo the hair and scalp using regular shampoo. Thoroughly rinse and towel dry the hair and scalp. Allow hair to air dry for a few minutes. Shake the permethrin lotion well before applying. Thoroughly wet the hair and scalp with the permethrin lotion. Be sure to cover the areas behind the ears and on the back of the neck also. Allow the lotion to remain in place for 10 minutes. Then, rinse the hair and scalp thoroughly and dry with a clean towel. When the hair is dry, you may want to comb the hair with a fine-toothed comb to remove any remaining nits (eggs) or nit shells.

Head lice can be easily transferred from one person to another by direct contact with clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or hairs from infected persons. Therefore, all members of your household should be examined for head lice and should receive treatment if they are found to be infected. If you have any questions about this, check with your doctor.

For the treatment of scabies (5% cream):

Read package directions carefully before using. Thoroughly wash and dry skin. Massage the cream into the skin from the head to the soles of the feet, paying special attention to creases in the skin, hands, feet, between fingers and toes, underarms, and groin. Scabies rarely infests the scalp of adults, although the hairline, neck, side of the head, and forehead may be infested in older people and in infants. Infants should be treated on the scalp, side of the head, and forehead. Leave the permethrin cream on the skin for 8 to 14 hours. Wash off by taking a shower or bath. Change into clean clothes. After treatment, itching may continue for up to 4 weeks.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage forms (cream and lotion): For head lice: Adults and children 2 years of age and older—Apply to the hair and scalp one time. Children up to 2 years of age—Use and dose must be determined by your doctor. For scabies: Adults and children 2 months of age and older—Apply to the skin one time. Children up to 2 months of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe drowsiness, stomach pain, or vomiting.


Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Onotrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Grapefruit and grapefruit juice may interact with simvastatin and lead to unwanted side effects. Avoid the use of grapefruit products while taking Onotrex.

Avoid eating foods that are high in fat or cholesterol. Onotrex will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.


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