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Refirm (Calcitriol)
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Refirm

Refirm is a synthetic version of Vitamin D3 used to treat calcium deficiency with hypoparathyroidism (decreased functioning of the parathyroid glands) and metabolic bone disease in people with chronic kidney failure.

Other names for this medication:
Alfabond, Alfacal, Arcium, Biocal, Calcibest, Calcikind, Calcimet, Calcor, Caldikind, Caldix, Calfa, Calotec, Calsonic, Caltin, Calzem, Carcal, Cholical, Devita, Dmcal, Ikmag, Koncal, Kurecal, Laretol, Lctrol, Novadee, Osteobel, Refirm, Rockbon, Solbiocal, Statbone, Vezocal

Similar Products:
Dostinex, Amoxil, Mysoline, Geodon, Elavil, Cleocin, Sinequan

Also known as: Calcitriol

Description

Generic Refirm is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Refirm are intestine and bone. Generic Refirm receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Refirm may also act on the kidney and the parathyroid glands. Generic Refirm is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Refirm has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Refirm, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Refirm in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Refirm produces other independent beneficial effects. Refirm is also known as Calcitriol. Generic Refirm treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Refirm is Calcitriol. Brand name of Generic Refirm is Refirm.

Dosage

Generic Refirm is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Refirm suddenly.

Overdose

If you overdose Generic Refirm and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Refirm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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