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Rocaltrol (Calcitriol)
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Rocaltrol

Rocaltrol is a man made form of vitamin D. It helps your body keep the proper levels of calcium and phosphorus and maintain healthy bones and teeth. Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Other names for this medication:
Actical, Admax, Alfabond, Alfacal, Alfacip, Apcical, Arcium, Aristrol, Biocitral, Calasto, Calbec, Calbory, Calbovic, Calcibest, Calcigra, Calcikind, Calcitriol, Caldikind, Calgel, Calosto, Calotec, Caltin, Caltop, Carcal, Coecoral, Devita, Dmcal, Fovit, Ikmag, Koncal, Laretol, Lctrol, Osteobel, Ostonex, Ostriol, Politrol, Refirm, Rical, Riecal, Ritoca, Roical, Rolsical, Sorvate, Sunmic, Tobalt, Trolec, Vezocal

Similar Products:
Casodex, Vermox, Altace, Actos, Effexor, Silagra, Evista

Also known as: Calcitriol

Description

Generic Rocaltrol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Rocaltrol are intestine and bone. Generic Rocaltrol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Rocaltrol may also act on the kidney and the parathyroid glands. Generic Rocaltrol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Rocaltrol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Rocaltrol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Rocaltrol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Rocaltrol produces other independent beneficial effects. Rocaltrol is also known as Calcitriol. Generic Rocaltrol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Rocaltrol is Calcitriol. Brand name of Generic Rocaltrol is Rocaltrol.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Rocaltrol. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Rocaltrol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rocaltrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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The primary outcome was the duration of complete sensory block to pinprick and time to complete recovery of pinprick. It contains 2460 base pairs that encode for a polypeptide chain of 820 amino acids. Correction to: 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. We employed a delayed feeding paradigm to assess regional brain catecholamine changes associated with insulin-elicited glucoprivic feeding. We have sought to determine if grading of liver injuries, as a clinical tool, affects immediate or extended management of patients.

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Post-infectious leukoencephalopathy as a complication of Mycoplasma pneumoniae infection. Oil exposure disrupts early life-history stages of coral reef fishes via behavioural impairments. A detailed comparison between Sps and thymomas shows that there exist several important clinicopathological and cytological differences between these two tumors. Responsible self-medication provides a positive health outcome for the individual and benefits for society as a whole. Sorting Out the Influence of Method of Detection, Access to Care, and Biologic Factors. Socioeconomic inequalities in low birth weight were larger in the United States than the other countries, suggesting that the more generous social safety nets and health care systems in the United Kingdom, Canada, and Australia played buffering roles. In particular, relatively light weakly coupled particles are predicted, with implications for collider searches.

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However, only limited information is available relating to how quickly they colonize ingested feed particles. Analyses by five major diagnostic groups showed that patients with a primary diagnosis of drug or alcohol abuse had the greatest overall frequency of arrests and also the greatest frequency of arrests for burglary, offenses against public order such as peace disturbance or loitering, and probation and parole violations. Fourfold or greater increases in IgG isohemagglutinins against blood group A cells were also found in 22 of 27 vaccines (mean increase 4.5-fold) and against blood group B cells in nine of 34 (mean increase 1.7-fold) using the indirect anti-human globulin test. Our study was designed to identify the genes involved in lung cancer progression targeted by NRF2. The Vat gene is a NBS-LRR gene that confers resistance to the aphid species Aphis gossypii and exhibits the unusual characteristic of also conferring resistance to non-persistently transmitted viruses when they are inoculated by the aphid. IDPN-induced axonal balloons containing accumulations of neurofilaments were equally well stained by bovine 150K and chicken neurofilament antisera. A phenomenologic comparison of primary and poststroke depression. In addition, several examples about the use of PRTs in mono or multi-enzymatic synthesis of NMP analogues are shown.

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Xenon reduces neurohistopathological damage and improves the early neurological deficit after cardiac arrest in pigs. The cDNA of cucumber mosaic virus-associated satellite RNA has in vivo biological properties. In addition, we analysed test-based cognitive ability data (i.e. Technique of surface modification of a cell-adhesion-resistant hydrogel by a cell-adhesion-available inorganic microarray. To assess the quality of reporting, a modification of an established quality assessment scale for retrospective clinical studies was used. These findings are interpreted as a result of the greater tendency for powerful individuals to process information selectively in line with the primary factors that drive cognition, such as affordances. Long-term renal fibrosis was assessed by measuring the hydroxyproline content.

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Here, we review recent breakthroughs in the structural studies of BoNT-protein receptor recognitions that highlight a range of diverse mechanisms by which BoNTs manipulate host neuronal proteins for highly specific uptake at neuromuscular junctions. It is feasible to carry out a rigorous randomized controlled trial in this group. The muscular weakness was relieved in seven weeks with intermittent hemodiafiltration. Immunopathologic mechanisms in lower respiratory tract disease of infants due to respiratory syncytial virus. Studies examined demonstrate the involvement of asporin in OA pathogenesis, and possible mechanisms by which asporin may be involved in this process have been proposed. The role of body weight has not been shown conclusively using objective outcome measures. At the bedside, the respiratory changes in left ventricular stroke volume can be assessed by the analysis of the arterial pressure (arterial catheter) or aortic blood velocity (echocardiography) wave forms. Psoriasis is a disease of major importance, the cause of which is unknown and treatment often difficult. Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX. Synthesis and antibacterial activity of pyridinium-tailored 2,5-substituted-1,3,4-oxadiazole thioether/sulfoxide/sulfone derivatives.

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An effective dose of strain SBT0270 to exert its hypocholesterolemic effect was 10(9) viable cells/d. The results demonstrated that atomization induces component segregation and fat-rich surfaces in spray-dried milk powders, and thus these cannot be prevented by adjusting the spray drying conditions. Polyomavirus-family and virus-specific PCR assays were designed and optimized for specificity and sensitivity. Antinatriuretic effect of exogenous metabolic substrates on the sodium diuresis of saline infusion. We found that mouldboard ploughing under CT was responsible for the spatial variability of herbicide degradation properties, whereas under MT herbicide degradation was associated to the vertical distribution of organic matter. This case shows how with detailed preoperative imaging, a minimally invasive approach is possible for the treatment of liposarcoma. Seventeen healthy subjects were studied with a 1.5-T scanner equipped with a whole body phased array coil system and 16-channel receivers. To this end, we have previously developed benzopyran-based HIF-1 inhibitors such as arylsulfonamide KCN1. For serial evaluation of large, heterogeneous lesions, the use of 3T short TE MRSI may thus be preferred. BCT9 act as growth modulating agents on Lactuca sativa seedlings.

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Analysis of bacterial cultures from 40 cases of periodontal abscess and their drug sensitivity. Both neuronal and nonneuronal factors contribute to the lack of CNS regeneration. Long-term morbidity is substantial because of xerostomia and severe dysphagia. Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein. Calculated pKa Variations Expose Dynamic Allosteric Communication Networks. Stimulation of a protective response apparently requires more than one exposure to the virus. Immunohistocemically, the tumor stained positive for S-100 protein but negatively for epithelial membrane antigen and glial fibrillary acidic tricor 145 mg side effects protein.

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The results are promising, in terms of both processing speed and performance. One possible strategy to reduce the risk of this complication would be the use of GnRH agonists instead of human chorionic gonadotrophin (hCG) to trigger the final stages of oocyte maturation. Characterization of the isolates by means of restriction endonuclease analysis showed that they were similar to reference strain SR49 (serotype 3) which is associated with inclusion body hepatitis in chickens. Transcriptional regulation, epigenetic modifications and chromatin structures are the key modulators in controlling such pluripotency nature of embryonic stem cell genomes, particularly in the developmental decisions and the maintenance of cell fates. Disease severity was increased by restraint stress in DSS-treated IFN-gamma(-/-) and Wt mice, accompanied by suppressed colonic pro and anti inflammatory cytokine responses. Long- and short-term outcomes of ERCP for bile duct stones in patients over 80 years old compared to younger patients: a propensity score analysis. Results from official jail data show the magnitude and extent of the problem. There were no differences in the proportion of comorbid psychiatric disorders or functional impairment between DSM-5 and ICD-11 criteria. However, inconsistencies have been found across studies bactrim dosage medscape that assess ToM and emotional processing as predictors of psychosis. We observed and scored behaviors and skills of supervisors in 11 categories deemed critical for effective and supportive supervision.

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To the best of our knowledge, this is the first time that intravascular ultrasound elastography has been validated in vivo. Culture and Family Process: Measures of Familism for Filipino and Korean American Parents. Evaluate the association of psychological distress with GERD, the robaxin 500mg dosage influence of psychological factors on symptoms, whether psychological distress is explained by a subset of GER patients, and if coexistence with IBS would be a surrogate marker. The aim of this study was to translate, cross-culturally adapt, and perform a psychometric validation of an Urdu translation of the Female Sexual Function Index (FSFI). Drug release was markedly increased when formulated as a solid dispersion with Poloxamer 407 and TPGS 1000. To study the reoperation rate after incontinence surgery and to compare the reoperation rates between different surgery types. The Hepatitis B and C Public Policy Association in cooperation with the Hellenic Center for Disease Prevention and Control together with 10 partner organizations discussed at the Athens High Level Meeting held in June 2014 recent policy developments, persisting and emerging challenges related to the prevention and management of viral hepatitis and the need for a de minimis framework of urgent priorities for action, reflected in a Call to Action (Appendix S1). Quantum Harmonic Oscillator State Control in a Squeezed Fock Basis.

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Thus increased competition for pollinators may generate stronger selection on attractive traits of flowers at high elevations and cause floral adaptive evolution. Searches were conducted using predetermined search terms and eligibility criteria, including papers in all languages. DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks. Iodinated melatonin mimics melatonin action and reveals discrete binding sites in fetal brain. Asian societies had the widest range of elderly/general ratios, ranging from 6.62 to 2.6. Four types of lipids with potential antihypertensive properties have recently been derived from the kidney. Ahnak-induced adipocyte differentiation was analyzed by Oil Red O staining.

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Adiposity, Dysmetabolic Traits, and Earlier Onset of Female Puberty in Adolescent Offspring of Women With Gestational Diabetes Mellitus: A Clinical Study Within the Danish National Birth Cohort. We demonstrate that by tuning the length and eluotropic strength of the pulses, peaks with retention factors in water, kw, above 150 can be manipulated to elute in 3-4 pulses. We conclude that the HGF causes similar redistribution of beta-catenin as Wnt-1 in the hepatocytes and that this effect is attributable to subcellular association of Met and beta-catenin. The influence of n-alkanols on DMPC ordering at twelve sites has been compared with that of cholesterol which is shown to interact with DMPC bilayers in a distinctly different manner from the n-alkanols. The effect of various energy-conversion states of chloroplasts on proton and electron transport. Chromatic dispersion measurement along both polarization directions of a birefringent hollow-core photonic crystal fiber using spectral interferometry.

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