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Zexate (Methotrexate)

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Zexate is a diagnostic aid. It is used to test if the adrenal glands are working properly. Zexate is used in the diagnosis of certain problems of the adrenal glands. These glands are located near the kidneys. The adrenal glands produce a steroid chemical called cortisol (hydrocortisone) that helps the body respond to stress or illness.

Other names for this medication:
Alltrex, Beltrax, Biotrexate, Caditrex, Carditrex, Cytotrex, Dermotrex, Folitrax, Imutrex, Merex, Methocip, Methorex, Methotrexate, Metorex, Metrex, Mexate, Neotrexate, Nidtrex, Oncotrex, Onotrex, Plastomet, Remtrex, Rextop, Roxate, Tevatrex, Throtex, Trixilem, Vibzi, Zexate

Similar Products:
Mysoline, Hydrea, Moduretic, Vermox, Maxalt, Danocrine, Revia, Ditropan, Duphaston

Also known as: Methotrexate


Zexate is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss. Brand name of Zexate is Zexate.


Usual Adult Dose of Zexate for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Zexate for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Zexate dosage information


If you overdose Generic Zexate and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zexate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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We retrospectively reviewed the files of 57 patients who were diagnosed with BCECTS between January 2008 and September 2013. In our small pilot study, we found more decisional conflict in those surrogates facing end-of-life decisions, specifically on the subset of questions dealing with uncertainty. Presenting symptoms including numbness, tingling, burning, and pain did not differ significantly between the 2 groups. The patients prescribed SCIT for allergic rhinitis and/or asthma in 2009-2011 were contacted in 2014 and asked whether they completed at least the 3 years of SCIT and/or whether they suspended the treatment for at least 2 months. In silico analysis predicted the presence of two potential ERE and 1 PRE in the mouse SP-D gene promoter region. We have studied the impact of stacking pattern on the electronic structure and electron/hole transport properties of these polytypes. Chemistry of lectins and their medical and biological applications. This suggests that ATRi can be used in combination therapies of lymphomas without the use of genotoxic drugs.

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Thus, the IGF pathway is required for head formation during embryogenesis. The aim of this study was to assess the efficacy and tolerability of mycophenolate mofetil (MMF) in neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD) in western China. The results show that fibroblasts of different species and originating tissues as well as bone-forming cells are able to attach to collagen membranes irrespective of collagen origin or mode of processing. Novel homozygous BMP9 nonsense mutation causes pulmonary arterial hypertension: a case report. Genomics, clinical research, and learning health care systems: Strategies to improve patient care. Thus, it can be inferred that genetic recombination has been important in the evolution of L.

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Topical delivery of five doses of 1.0 percent prednisolone acetate at 1-minute intervals each hour results in an antiinflammatory effect comparable to that achieved by instillation every 15 minutes. gondii and probably against other foreign pathogens occurring in the ocean environment. In this condition, MCI-186 in the late period decreased the number of apoptosis cells induced by bleomycin, and therefore it might contribute to the deterioration of pulmonary fibrosis. The group agreed that MRI does not represent a validated surrogate in any clinical form of MS. The holes were colocalized with the possible positions of the target at distances ranging from 25 to 35 cm. We found that recurrent cholesteatoma was associated with diminished postoperative hearing. Recently, physiological roles for retinoic acid-related orphan receptor alpha (RORalpha) have been implicated in cardiovascular diseases such as atherosclerosis. Herein, we disclose further efforts to the optimization of hit compound (-)-6, which led to the identification of aminocyclohexene analogues (-)-9 and (-)-17 with good potency, high selectivity, and minimal CYP inhibition. The fistula was repaired using a pedicled nasoseptal mucosal flap.


Insulin and glucose levels were measured in 13 orthotopic liver transplantations in pigs. Descriptive statistics and fixed effects logistic regression models with a rare event correction are used to analyze the data. Recent studies have identified specific OSE as major targets of both cellular and soluble pattern recognition receptors of the innate immune system, including innate natural IgM antibodies. The most frequent finding after a 4-year follow-up was conversion on GDx. Role of PI3K, MAPK/ERK1/2, and p38 in implementation of the proliferative and differentiation potential of erythroid progenitors after blood loss. Risk factors for relapse in stage IB1 cervical cancer were analized and identified by the following statistical tests-Kaplan-Meier, Cox regression, Log-rank test, Breslow and Tarone-Ware tests.

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Peri-operative blood transfusion for resected colon cancer: Practice patterns and outcomes in a population-based study. Spleen cells taken 4 days after lethal irradiation of Lewis rat were used as a source of radioresistant accessory cells. Inhibitors targeting pUL56 and/or pUL89 may offer an attractive alternative since mammalian cell DNA replication does not involve cleavage of concatameric DNA. Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone. Effects of fluid shear stress on polyelectrolyte multilayers by neutron scattering studies. In parallel, pharmacokinetic investigations were performed in some pts in phase I A and IB. Frustration and anomalous behavior in the Bell-Lavis model of liquid water. Challenges and opportunities for hydrogen production from microalgae. Further studies examining the effects of raw versus cooked vegetables are needed. An earlier study yielded six scores but the present one suggests that one of them should be broken into two, yielding seven scores.

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Thus, the central cell nucleus might also serve as a site that organizes F-actin cytoskeleton to promote sperm cell nucleus movement and karyogamy. Cisplatin in combination with metronomic vinorelbine as front-line treatment in advanced non-small cell lung cancer: a multicenter phase II study of the Hellenic Oncology Research Group (HORG). We show that salidroside induced significant apoptosis in the human chondrosarcoma cell line SW1353. The determination of high-resolution structures of some ribotoxins, the characterization of a large number of mutants, and the use of lipid model vesicles and transformed cell lines have been the tools used for the study of their mechanism of action at the molecular level. Data of patients who received revascularisation for DES restenosis between 2004 and 2011 were collected. Stress concentration effects are significant in ten of the 11 tests. We examine the time variations in consumer behaviour and how this is statistically aggregated into larger traffic loads on national core fibre communications networks. High expression of HOXA13 correlates with poorly differentiated hepatocellular carcinomas and modulates sorafenib response in in vitro models. Treatment of osteoporosis in men using dehydroepiandrosterone sulfate.

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by surface structures determining the rate of bacterial elimination from the lungs and by the lipoprotein components of the cell walls inducing the leucocytes mobilization into bronchial tissue. The patients were actively followed up for 1 year with radiological assessment to observe fracture healing, alignment, reduction, and necrosis and by functional outcome measurements, including Constant, Disabilities of the Arm, Shoulder and Hand (DASH), and Neer scores. The superficial femoral artery perforator (SFAP) flap offers advantages for pedicled transfer including consistent perforators and vascular territory, well-hidden donor site scar, and hairless flap skin. A 6 hr advance or delay of a LD 12:12 light-dark cycle produced a corresponding shift in the melatonin rhythm. Telephone counseling in psychosocial oncology: a report from the Cancer Information and Counseling Line.

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Polychlorinated compounds with PPAR-gamma agonistic effect from the medicinal fungus Phellinus ribis. Increasing tumor vascularity is highly correlated with ulceration, possibly helping to explain the biologic basis of this known prognostic factor. This paper aims to generalize the design of continuous-time filters to the fractional domain with different orders and validates the theoretical results with two different CCII based filters. Correction of structural knee deformities by high subchondral osteotomy in the elderly. Placental PGDH activity changed strikingly according to the day of pregnancy. Gestation in women with kidney disease: prognosis and management. Antioxidant activity of rosemary essential oil fractions obtained by molecular distillation and their effect on oxidative stability of sunflower oil. The study also provides an insight for HIV/AIDS mapping and possible future direction of the epidemic in India. Nasopharyngeal swabs were collected from children with asthma, those in asthma remission, and control groups.


Optimal esophageal balloon volume for accurate estimation of pleural pressure at end-expiration and end-inspiration: an in vitro bench experiment. A technique for the stabilization of atlantoaxial subluxation in the dog was developed. Long lasting changes in RNA synthesis in the forebrains of female rats treated with testosterone soon after birth. Age-corrected values are indispensable in assessing discrete changes in light difference sensitivity (LDS) when evaluating perimetric results. Differences in the pollen morphology were found in the studied species, mainly in terms of shape, pollen aperture and ornamentation pattern of the exine. Using self-assembled gold nanoshell monolayers, we produce a 10-fold increase in the PL of 2D TMDCs.

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To evaluate the contribution of periactin medication side effects Dnmt1 to the DNA methylation in male germ cells, the expression profiles of Dnmt1 in embryonic gonocytes were investigated. A competitive enzyme immunoassay was developed to measure the changes in serum levels of ovotransferrin (OTF) during inflammation and infectious diseases in chickens. No pharmacokinetic data are available with respect to the plasma concentration of ketoprofen during intravenous infusion in children. Positive self-concept protects the person from the harm that stigma may cause on his well-being. Bronchoalveolar lavage for the preparation of free lung cells: technique and complications. Rats were trained to criterion in successive reversals of a classically conditioned heart-rate discrimination. Effect of sarcolysine on H3-thymidine incorporation in DNA of cells of surviving sections of sarcoma 298. The sample consisted of 510 consecutive, unselected pregnant women of gestational age between 11 and 14 weeks, who had attended a nuchal translucency (NT) screening. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. There is a lack of meta-analysis on PBDE concentrations in human breast milk worldwide.

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Liquid chromatography and fluorescence spectroscopy compared with a homogeneous enzyme immunoassay technique for determining quinidine in serum. In this study, we evaluated the effect of PEG-UK targeted to ischemic tissue with microcirculation failure in rat model of ischemic stroke and investigated the possible mechanisms of action. Extracts from xeroderma pigmentosum cell lines fail to act on damaged circular DNA, but are proficient in repair synthesis of ultraviolet-irradiated DNA containing incisions generated by Micrococcus luteus pyrimidine dimer-DNA glycosylase. Programs and their ratings of personal, structural, and clinical care challenges were described statistically. We investigated the efficacy of rivaroxaban in preventing EHIT and DVT after endovenous laser ablation (EVLA). Immunological assay of beta-1-SP-1-glycoprotein applied to obstetric diagnosis: review of the literature and serum levels in normal and pathological pregnancies. So Cnx1 is likely to be the anchor protein for the whole biosynthesis complex on actin filaments. Through a differential expression analysis, miRNAs associated with Beet necrotic yellow vein virus (BNYVV) infection were identified and confirmed using a microarray analysis and stem-loop RT-qPCR. The present study compared participants with major depression (MDD), panic disorder (PD), comorbid MDD/PD and controls on neuropsychological measures of visuospatial processing, Judgement of Line Orientation (JLO), and mathematical abilities, Wide Range Achievement Test (WRAT) Arithmetic. To explore the function of the protease-resistant IGFBP-4 in vivo, expression of the mutant and native proteins was targeted to SMC of transgenic mice by means of a smooth muscle alpha-actin promoter.

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In order to maintain the deuterium label during LC/MS analyses, chromatographic separation must be done rapidly (usually in under 8-10 min) and at 0 degrees C. The potential of mean force and the cage lifetime results give additional explanations for the proposed nucleation of gas hydrates at gas-water interfaces. A difference of eight points was considered clinically relevant. The antagonism by thymoleptics of the reserpine-induced expansion of melanophores in the pencil fish. Human adipose-derived mesenchymal stem cells seeded into a collagen-hydroxyapatite scaffold promote bone augmentation after implantation in the mouse. However, substantial risk factor reductions have not been achieved across all Europe. As far as is known, no previous case has been reported where a combination of pelvic fracture and superior gluteal artery bleed has led to acute gluteal and thigh compartment syndrome.

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Given that their simultaneous unintentional exposure occurs in wildlife and also in human infants, data on mixture effects of combined exposures to these hormones during development is needed. Notch1 controls cell chemoresistance in small cell lung carcinoma cells. This analgesic effect of DAMGO was significantly enhanced by the genetic depletion of RGS4 or by coadministration of CCG50014 (10 nmol). Personal recollections on Fritz Lipmann during the early years of coenzyme A research. If YouthCHAT is found to be acceptable to study participants and as effective as a HEEADSSS assessment, it could be an innovative and more efficient means of routine screening for common psychosocial health issues in young people with and without long-term physical conditions. Follow-up computed tomography demonstrated viramune suspension cost occlusion of the left external iliac artery and patent crossover bypass. Pertrochanteric fractures: tips and tricks in nail osteosynthesis. The multiple stressor ecological risk assessment for the mercury-contaminated South River and upper Shenandoah River using the Bayesian network-relative risk model. Patterns of epidermal growth factor receptor mutation in non-small-cell lung cancers in the Gulf region. The differential diagnoses included adenosarcoma, endometrial stromal sarcoma, and, less likely, malignant mesodermal mixed tumor (MMMT/carcinosarcoma).

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We also found that the two loop regions close to the FMN-binding site are disordered in apo-TdsC and become structured upon FMN binding. To address this issue, we devised a novel ultrasonographic procedure for assessing vocal cord movement indirectly by observing the arytenoid movement from a lateral view. Complication rate are higher for extremity tissue expansion, and proper caution must be adopted if this concept is to be valuable for applications in the extremities. Correlation tests and principal component analysis suggest that the underlying limestone bedrock controls pH and weathering reactions. Smoking does biaxin cure urinary tract infection is a chronic process in which craving and negative affect are considered the main barriers to maintaining abstinence in patients who have gone through treatment. Repressive effects of oat extracts on intracellular lipid-droplet formation in adipocytes and a three-dimensional subcutaneous adipose tissue model.

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Flexible cystoscopy via a suprapubic cystostomy tract was utilized to locate the proximal segment of a complete traumatic disruption of the bulbar urethra secondary to a pelvic fracture. We conclude that IFT velocity is governed by (i) the absolute numbers of each motor type on a given train, (ii) how prone KIF3AB is to dissociation from MTs relative to KIF17, and (iii) how prone both motors are to dissociation relative to binding MTs. The resulting model enables the calculation of probabilities of pregnancy and twin pregnancy. As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. To observe the effects of metformin (MET) on podocalyxin (PCX) expression in renal tissue from type 2 diabetes mellitus (T2DM) model rats and investigate its protective effects against glomerular podocyte injury.

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Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain. Total Marrow Lymphoid Irradiation/Fludarabine/ Melphalan Conditioning for Allogeneic Hematopoietic Cell Transplantation. Lactate is a biomarker for hypoperfusion and subsequent resuscitation in trauma. Role strain was positively correlated with desire for promotion and leadership, as well as with intent to leave. First, binding required the presence of p-chloromercuriphenylsulfonic acid and bound angiotensin II was released by dithiothreitol.

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This study is a randomized clinical trial in which 60 breastfeeding mothers complaining of hypogalactia and meeting the inclusion criteria were studied. An investigation of ketoacidosis in children with newly diagnosed type 1 diabetes. Both in vitro and in vivo experiments have confirmed that platelet-rich plasma has therapeutic effects on many neuropathies, but its effects on carpal tunnel syndrome remain poorly understood. State-level factors investigated were tobacco control program funding, tobacco taxes, smoke-free air policies, state anti-smoking sentiment and recent change in smoking prevalence. Patients completed a 7-item measure of HPRQ and measures of treatment and self-management burden, chronic condition distress, self-efficacy, provider satisfaction, medication adherence, and physical and mental health. We modeled the distribution of 288 vertebrate species (amphibians, birds and mammals), all endemic to the Amazon basin, using different combinations of the following inputs known to affect the outcome of species distribution models (SDMs): 1) biological data type, 2) modeling methods, 3) greenhouse gas emission scenarios and can bactrim treat upper respiratory infection 4) climate forecasts. The first kind corresponds to the internal molecular modes, which are coupled to the electronic propagation along the molecular bridges. The relationships which they may present with a plasma protein, cold insoluble globulin, are discussed together with the important role which they seem to play in the phenomena of cell adhesiveness.

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To address this, we analysed associations between lipometry, early metabolic and preatherosclerotic symptoms and adiponectin subfractions in 71 obese juveniles and 75 normal weight controls of similar age and gender distribution. RT-PCR and Northern blot analysis were used to assess the regional abundance of the mRNA of this channel. The localization of cholesteatoma was classified as attic, sinus, or tensa. This approach, directly removing excited energy at the fundamental origin of cellular photodegradation, indicates an important first step towards the practical use of DUV imaging in a variety of biological applications. The treatment of varices calls for complete thrombosis of all varicose veins, and merits and demerits of available treatment modalities are discussed based on autopsies from the pathologic point of view. Further analysis of data on radiation exposure, controlling for exposures to asbestos and welding, found reductions in initial estimates of radiation risk at all levels of radiation exposure. Age of transfused red cells and early outcomes after cardiac surgery. Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin. Inappropriate HLA-DR expression is present in the bronchi -alveolar epithelium in IPF. Here they suggested asymptomatic abdominal aortitis in half the patients.

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