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Zudena (Udenafil)
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Zudena

Zudena does not have a direct relaxing effect on a cavernous body, but upon sexual stimulation enhances the relaxing effect of nitric oxide by inhibiting PDE-5, which is responsible for the breakdown of cGMP in the cavernous body.

Other names for this medication:
Udenafil, Udzire, Zydena

Similar Products:
Compazine, Strattera, Rebetol, Differin, Zanaflex, Hytrin

Also known as: Udenafil

Description

Zudena is a newly designed anti-impotence medication produced by Sunrise Remedies Ltd. Zudena contains an active ingredient Udenafil, which is a recently approved PDE-5 inhibitor. Udenafil starts working in response to sexual arousal by stimulating the production of nitric oxide (NO) in the corpus cavernosum. Nitric oxide activates the lyase enzyme which is followed by increasing levels of cyclic guanosine monophosphate (cGMP). This cyclic nucleotide relaxes smooth muscles in blood vessels of the corpus cavernosum, increasing blood flow and thus inducing an erection. Zudena has a rapid onset action reaching a peak plasma concentration between 1 to 1,5 hours and its half-life is 11-13 hours, meaning Zudena has a long duration of action. Zudena does not protect you or your partner from sexually transmitted diseases (including HIV) or from pregnancy.

Dosage

Zudena should be taken orally with a full glass of water. Recommended dose: one tablet per day taken 30 minutes before planned sexual activity. The maximum recommended dose is 1 time per day. The dose may be increased to two tablets per day if individual tolerability is taken into account.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zudena are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Zudena if you are allergic to its components. Do not take Zudena if you are also using organic nitrates, nitrate drugs for chest pain or heart condition (e.g., nitroglycerin, isosorbide dinitrate and isosorbide mononitrate), nitrates as amyl nitrate or nitrite ("poppers"). Do not take Zudena if you take other medication to treat erectile dysfunction or pulmonary arterial hypertension, such as riociguat (Adempas). Do not take Zudena if you are taking erythromycin, alpha-blockers, ketoconazole, itraconazole (Sporanox or Nizoral), ritonavir (Norvir) or indinavir (Crixivan). Do not consume alcohol while using Zudena, as it can lower your blood pressure, causing dizziness and rapid heart rate (tachycardia). Do not drive or operate machinery while taking the medication. Contact you doctor or health care professional right away if your erection lasts longer than 4 hours or if it becomes painful. Zudena does not protect you or your partner from sexually transmitted diseases or pregnancy. Zudena can be dangerous for children and women.

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Ameliorative effect of borneol, a natural bicyclic monoterpene against hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic Wistar rats. In one patient a gastric bleeding was seen on the first postoperative day. This is a retrospective chart and radiographic review of all inserted CVADs found malpositioned between 1996-2014 in a multi-specialty 1000-bed tertiary trauma center in Sydney, Australia.7450 CVADs placed by a nurse-led vascular access service were reviewed. INK-128 inhibited colorectal cancer cell growth and survival, and induced both apoptotic and non-apoptotic cancer cell death. The uses and limitations of acid phosphatase as a tumor marker, as well as particular difficulties in measuring tumor response in the disease, are detailed herein. Effect of time on the shear bond strength of cyanoacrylate and composite orthodontic adhesives. Modern intensive poultry production favours the introduction of infection into commercial growing units, resulting in intestinal colonization during the second to fourth weeks inclusive. Data on gene expression patterns during development have indicated ADVR homology with parts of the latter two structures rather than with LNC.

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Effects of telencephalic ablation on habituation of arousal responses, within and between daily training sessions in goldfish. Thermogravimetric analysis for rapid assessment of moisture diffusivity in polydisperse powder and thin film matrices. Physical health was reduced compared with the adjusted general population at 10 years after injury. There is growing concern with the increasing prevalence of obesity in industrialised countries, a trend that is more apparent in the poor than in the rich. Based on findings showing a relationship between gut microbiota and RA, we investigated whether the change of gut microbiota induced by P. Sonography of subcutaneous tissue cannot determine causes of lower limb edema. Phthalides as promising insecticides against Tuta absoluta (Lepidoptera: Gelechiidae). Pneumocystic Carinii pneumonia in a renal transplant recipient: diagnosis by transbronchial biopsy: a case report and review of the literature.

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Primary Hemiarthroplasty for Proximal Humeral Fractures in the Elderly: Long-Term Functional Outcome and Social Implications. Using a team-based approach, health sciences librarians are communicating to integrate research and teaching support, systems differences across dispersed campuses, and future needs of a new community-based medical program. Vector mode conversion based on an asymmetric fiber Bragg grating in few-mode fibers. Chief complaint, past medical/surgical history, medications, procedure performed, intraoperative findings, intraoperative complications, and postoperative recovery were reviewed. The Neurocritical Care Society recruited experts in neurocritical care, nursing, and pharmacotherapy to form a writing Committee in 2015.

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